Detailed information NTG0502743

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HWI43_RS04620
• Genome accession: NZ_CP064528
• Coordinates: 988570..989616 (+)
• Length: 348 a.a.
• NCBI ID: WP_002447441.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain UMCG370
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 983570..994616

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HWI43_RS04595 (HWI43_04540)	isaB	984710..985246 (+)	537	WP_002447446.1	immunodominant staphylococcal antigen IsaB family protein	-
HWI43_RS04600 (HWI43_04545)	-	985398..986384 (-)	987	WP_002447445.1	aromatic acid exporter family protein	-
HWI43_RS04605 (HWI43_04550)	map	986558..987313 (+)	756	WP_002447444.1	type I methionyl aminopeptidase	-
HWI43_RS04610 (HWI43_04555)	-	987471..987857 (+)	387	WP_002495657.1	hypothetical protein	-
HWI43_RS04615 (HWI43_04560)	liaF	987872..988573 (+)	702	WP_002447442.1	cell wall-active antibiotics response protein LiaF	-
HWI43_RS04620 (HWI43_04565)	vraS	988570..989616 (+)	1047	WP_002447441.1	sensor histidine kinase	Regulator
HWI43_RS04625 (HWI43_04570)	vraR	989606..990235 (+)	630	WP_002473914.1	two-component system response regulator VraR	Regulator
HWI43_RS04630 (HWI43_04575)	-	990292..991470 (-)	1179	WP_408020721.1	YihY/virulence factor BrkB family protein	-
HWI43_RS04635 (HWI43_04580)	-	991876..992160 (-)	285	WP_002447438.1	YtxH domain-containing protein	-
HWI43_RS04640 (HWI43_04585)	-	992168..992632 (-)	465	WP_070593291.1	low molecular weight protein-tyrosine-phosphatase	-
HWI43_RS04645 (HWI43_04590)	-	992774..992989 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
HWI43_RS04650 (HWI43_04595)	-	992991..994232 (+)	1242	WP_002458545.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40114.53 Da
• Isoelectric Point: 5.8512

>NTDB_id=502743 HWI43_RS04620 WP_002447441.1 988570..989616(+) (vraS) [Staphylococcus epidermidis strain UMCG370]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVFLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVLHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=502743 HWI43_RS04620 WP_002447441.1 988570..989616(+) (vraS) [Staphylococcus epidermidis strain UMCG370]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAAGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTTTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCC
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACTATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAGAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCAAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCAATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTTTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.442	98.851	0.914