Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   KME66_RS27225 Genome accession   NZ_CP076457
Coordinates   6216928..6219969 (+) Length   1013 a.a.
NCBI ID   WP_216327017.1    Uniprot ID   -
Organism   Streptomyces sp. YPW6     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 6211928..6224969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KME66_RS27210 (KME66_27210) - 6214179..6215195 (+) 1017 WP_073217516.1 TerC family protein -
  KME66_RS27215 (KME66_27215) - 6215396..6216052 (-) 657 WP_073217511.1 MBL fold metallo-hydrolase -
  KME66_RS27220 (KME66_27220) - 6216063..6216752 (-) 690 WP_216327014.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  KME66_RS27225 (KME66_27225) uvrA 6216928..6219969 (+) 3042 WP_216327017.1 excinuclease ABC subunit UvrA Machinery gene
  KME66_RS27230 (KME66_27230) - 6220368..6220796 (+) 429 WP_073217502.1 Rieske (2Fe-2S) protein -
  KME66_RS27235 (KME66_27235) - 6221156..6222088 (-) 933 WP_073217499.1 hypothetical protein -
  KME66_RS27240 (KME66_27240) - 6222316..6222966 (+) 651 WP_253208491.1 papain-like cysteine protease family protein -
  KME66_RS27245 (KME66_27245) - 6222971..6223978 (+) 1008 WP_216327023.1 hypothetical protein -

Sequence

Protein


Download         Length: 1013 a.a.        Molecular weight: 110594.73 Da        Isoelectric Point: 7.5819

>NTDB_id=502691 KME66_RS27225 WP_216327017.1 6216928..6219969(+) (uvrA) [Streptomyces sp. YPW6]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECRRPISRQSPQAIVDKVLGLPEGSRFQVLSPLVRERK
GEFVDLFADLQTKGYSRARVDGETIQLAEPPALKKQEKHTIEVVVDRLTVKDSAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCPYDDLSFEELEPRSFSFNSPFGACPDCTGIGTRMEVDPELIVPDEEKSLDEGAIHPWSHGHTK
EYFGRLIGALSEALGFRTDIPWAGLPQRAKKALLFGHKIQTEVRYRNRYGRERAYTTPAFEGAVQFVKRRHTEAESDSSR
ERFEGYMREVPCPTCEGTRLKPIVLAVTVMEKSIAEVAAMSISECAEFLGRLKLNARDKKIAERVLKEVNERLKFLVDVG
LDYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVA
DWVVDIGPGAGEHGGKVVHSGSLKELLGNKASITGQYLSGKRSIPTPDARRPVDPDRSLTVHGARENNLQDIDVSFPLGV
LTAVTGVSGSGKSTLVNDILYTHLARELNGAKSVPGRHTRVDGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHVRKLF
AETMEAKVRGYLPGRFSFNVKGGRCENCSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKSIAEVLDMPIEE
GLEFFEAVPAIARHLRTLNDVGLGYVRLGQSAPTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDISKLITVL
SGLVDKGNSVIVIEHNLDVIKTADWVVDMGPEGGNGGGLVVAEGTPEQVASVPASHTGKFLQGILDADRIAEAAVPSGGA
PRGTAARKAAPAKKTAATTKSAAAKKAAATKAKATATGTKAAAAKKTTRARKA

Nucleotide


Download         Length: 3042 bp        

>NTDB_id=502691 KME66_RS27225 WP_216327017.1 6216928..6219969(+) (uvrA) [Streptomyces sp. YPW6]
GTGGCCGACCGTCTCATCGTCCGTGGCGCGCGCGAGCACAATCTGAAGAACGTCTCGCTCGACCTCCCCCGCGACTCCCT
CATCGTCTTCACCGGGCTCTCCGGGTCGGGCAAGTCGTCCCTCGCGTTCGACACGATCTTCGCCGAGGGGCAGCGTCGCT
ATGTCGAGTCCCTCTCCTCGTACGCCCGGCAGTTCCTCGGCCAGATGGACAAGCCGGACGTCGACTTCATCGAAGGTCTC
TCCCCGGCCGTCTCCATCGACCAGAAGTCGACCTCGCGCAACCCGCGCTCGACGGTCGGCACCATCACCGAGGTCTACGA
CTACCTCCGGCTGCTCTTCGCCCGGATCGGCAAGCCGCACTGTCCCGAGTGCCGTCGCCCCATCTCCCGCCAGTCGCCGC
AGGCCATCGTCGACAAGGTCCTCGGTCTGCCCGAGGGCAGCCGCTTCCAGGTCCTCTCGCCGCTGGTGCGCGAGCGCAAG
GGCGAGTTCGTCGACCTCTTCGCCGATCTCCAGACCAAGGGCTACAGCCGCGCCCGGGTGGACGGCGAGACCATCCAGCT
CGCCGAGCCGCCGGCACTCAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCGTCGACCGCCTCACCGTCAAGGACAGCG
CCAAGCGCCGGCTGACCGACTCGGTCGAGACCGCGCTCGGCCTCTCCGGCGGCATGGTCGTGCTCGACTTCGTCGACCTC
CCCGAGGACGACCCCGAGCGCGAGCGGATGTATTCCGAGCACCTCTACTGCCCGTACGACGACCTCTCCTTCGAGGAGCT
GGAGCCGCGCTCCTTCTCCTTCAACTCGCCCTTCGGCGCCTGCCCCGACTGCACCGGCATCGGTACGCGCATGGAGGTCG
ACCCGGAGCTGATCGTCCCGGACGAGGAGAAGTCCCTCGACGAGGGAGCCATCCACCCCTGGTCCCACGGGCACACCAAG
GAGTATTTCGGCCGTCTGATCGGCGCGCTCTCCGAAGCCCTCGGCTTCCGTACGGACATCCCCTGGGCCGGGCTGCCGCA
GCGGGCCAAGAAGGCCCTGCTCTTCGGTCACAAGATCCAGACCGAGGTCCGCTACCGCAACCGCTACGGGCGCGAGCGCG
CCTACACCACCCCCGCCTTCGAGGGCGCGGTGCAGTTCGTCAAGCGGCGCCACACCGAGGCCGAGAGCGACTCCAGCCGG
GAGCGCTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCCACCTGTGAGGGCACCCGGCTCAAGCCGATCGTCCTCGCGGT
GACGGTGATGGAGAAGTCCATCGCCGAGGTCGCCGCGATGTCCATCAGCGAGTGCGCCGAGTTCCTCGGCCGCCTCAAGC
TGAACGCCCGCGACAAGAAGATCGCCGAACGGGTGCTCAAGGAGGTCAACGAGCGGCTGAAGTTCCTGGTGGACGTCGGC
CTGGACTACCTCTCGCTGAACCGTGCGGCAGGCACCCTGTCCGGCGGCGAGGCCCAGCGCATCCGGCTGGCCACCCAGAT
CGGTTCCGGCCTGGTCGGCGTGCTGTACGTCCTGGACGAGCCGTCCATCGGCCTGCACCAGCGCGACAACCACCGGCTGA
TCGAGACCCTGGTCCGGCTGCGTGACATGGGCAACACGCTCATCGTCGTCGAGCACGACGAGGACACCATCAAGGTCGCC
GACTGGGTCGTGGACATCGGCCCCGGCGCCGGTGAGCACGGCGGCAAGGTCGTCCACTCCGGTTCGCTCAAGGAGCTGCT
GGGGAACAAGGCCTCGATCACCGGCCAGTACCTGTCCGGCAAGCGGTCCATCCCGACCCCGGACGCCCGCCGCCCGGTCG
ACCCGGACCGCTCCCTCACCGTGCACGGCGCCCGGGAGAACAACCTCCAGGACATCGACGTCTCCTTCCCGCTCGGCGTG
CTCACCGCTGTCACGGGCGTCTCCGGATCCGGGAAGTCGACCCTGGTCAACGACATCCTCTACACGCACCTGGCCCGCGA
GCTGAACGGCGCCAAGTCGGTCCCCGGCCGCCACACCCGGGTCGACGGCGACGACCTCGTCGACAAGGTGGTGCACGTCG
ACCAGTCGCCGATCGGCCGGACCCCCCGGTCCAACCCGGCGACGTACACCGGAGTCTTCGACCACGTCCGCAAGCTGTTC
GCCGAGACCATGGAGGCGAAGGTGCGCGGCTATCTGCCGGGCCGCTTCTCCTTCAACGTCAAGGGCGGCCGCTGCGAGAA
CTGCTCCGGCGACGGCACGATCAAGATCGAGATGAACTTCCTGCCCGACGTGTACGTCCCGTGCGAGGTCTGCCACGGTG
CGCGCTACAACCGGGAGACCCTGGAGGTCCACTACAAGGGCAAGTCCATCGCCGAGGTGCTGGACATGCCGATCGAGGAG
GGCCTGGAGTTCTTCGAGGCCGTCCCGGCGATCGCCCGCCATCTGCGCACCCTCAATGACGTGGGCCTCGGCTACGTCCG
GCTCGGCCAGTCCGCGCCGACCCTCTCCGGCGGTGAGGCGCAGCGCGTCAAGCTGGCGAGCGAGCTCCAGAAGCGCTCCA
CCGGCCGCACGGTCTACGTCCTGGACGAGCCGACCACCGGTCTGCACTTCGAGGACATCAGCAAGCTGATCACGGTGCTC
TCGGGTCTGGTGGACAAGGGCAACTCGGTGATCGTCATCGAGCACAACCTCGACGTCATCAAGACCGCCGACTGGGTGGT
CGACATGGGCCCCGAGGGCGGCAACGGCGGCGGACTGGTCGTCGCCGAGGGAACACCGGAGCAGGTCGCCTCGGTGCCCG
CCAGCCACACCGGGAAGTTCCTCCAGGGCATTCTGGACGCGGACCGGATCGCCGAGGCCGCGGTGCCCTCGGGCGGGGCT
CCCCGCGGGACGGCCGCCCGCAAGGCCGCCCCGGCGAAGAAGACGGCGGCCACGACGAAGTCGGCAGCCGCCAAGAAGGC
CGCGGCGACCAAGGCGAAGGCCACGGCCACCGGCACCAAGGCCGCGGCCGCCAAGAAGACGACCCGAGCCCGCAAGGCCT
GA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(629-865)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-404)

UvrA interaction domain (UvrA_inter)

(131-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

56.586

93.682

0.53
  uvrA Streptococcus pneumoniae TIGR4

56.586

93.682

0.53
  uvrA Streptococcus pneumoniae D39

56.586

93.682

0.53