Detailed information NTG0502569

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: HWI48_RS06175
• Genome accession: NZ_CP064512
• Coordinates: 1298289..1298606 (+)
• Length: 105 a.a.
• NCBI ID: WP_001831271.1
• Uniprot ID: A0A9Q5JKE9
• Organism: Staphylococcus epidermidis strain UMCG375
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1293289..1303606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HWI48_RS06145 (HWI48_06120)	-	1294066..1294266 (+)	201	WP_001831138.1	YqgQ family protein	-
HWI48_RS06150 (HWI48_06125)	-	1294266..1295252 (+)	987	WP_001831113.1	ROK family glucokinase	-
HWI48_RS06155 (HWI48_06130)	-	1295252..1295578 (+)	327	WP_001831234.1	MTH1187 family thiamine-binding protein	-
HWI48_RS06160 (HWI48_06135)	-	1295578..1296201 (+)	624	WP_001831016.1	MBL fold metallo-hydrolase	-
HWI48_RS06165 (HWI48_06140)	comGA	1296258..1297232 (+)	975	WP_001831109.1	competence type IV pilus ATPase ComGA	Machinery gene
HWI48_RS06170 (HWI48_06145)	comGB	1297204..1298271 (+)	1068	WP_001831131.1	competence type IV pilus assembly protein ComGB	Machinery gene
HWI48_RS06175 (HWI48_06150)	comGC	1298289..1298606 (+)	318	WP_001831271.1	competence type IV pilus major pilin ComGC	Machinery gene
HWI48_RS06180 (HWI48_06155)	comGD	1298596..1299033 (+)	438	WP_001831025.1	competence type IV pilus minor pilin ComGD	-
HWI48_RS06185 (HWI48_06160)	-	1299020..1299313 (+)	294	WP_001831116.1	hypothetical protein	-
HWI48_RS06190 (HWI48_06165)	-	1299237..1299728 (+)	492	WP_002440043.1	competence type IV pilus minor pilin ComGF	-
HWI48_RS06195 (HWI48_06170)	-	1299893..1300405 (+)	513	WP_002440040.1	shikimate kinase	-
HWI48_RS06200 (HWI48_06175)	gcvT	1300623..1301715 (+)	1093	Protein_1182	glycine cleavage system aminomethyltransferase GcvT	-
HWI48_RS06205 (HWI48_06180)	gcvPA	1301735..1303081 (+)	1347	WP_002456181.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11491.58 Da
• Isoelectric Point: 9.7429

>NTDB_id=502569 HWI48_RS06175 WP_001831271.1 1298289..1298606(+) (comGC) [Staphylococcus epidermidis strain UMCG375]
MKTLKLLKKTRAFTLIEMLLVLLIISLLLILIIPNIAKQTSHIQSTGCDAQVKMVNSQIEAYALKHNRNPSNIDDLVSDG
FIKEGQKTCKSGQTISIANGEAVAN

Nucleotide

• Length: 318 bp

>NTDB_id=502569 HWI48_RS06175 WP_001831271.1 1298289..1298606(+) (comGC) [Staphylococcus epidermidis strain UMCG375]
ATGAAAACATTGAAATTATTGAAAAAAACACGAGCATTTACCTTGATAGAAATGCTTTTAGTATTACTAATAATAAGTTT
ATTGTTAATACTTATAATTCCAAATATTGCAAAACAAACATCTCATATTCAGTCAACTGGATGTGATGCTCAAGTTAAAA
TGGTAAACAGTCAAATAGAAGCCTACGCTTTAAAACATAATCGCAACCCTTCTAATATTGATGATTTGGTTTCAGATGGT
TTTATAAAAGAAGGACAAAAAACATGTAAATCCGGTCAGACAATTAGTATTGCAAATGGAGAAGCAGTTGCCAATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-32)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Staphylococcus aureus MW2	87.255	97.143	0.848
comGC	Staphylococcus aureus N315	87.255	97.143	0.848
comGC/cglC	Streptococcus mitis SK321	44.66	98.095	0.438
comGC/cglC	Streptococcus pneumoniae TIGR4	44.681	89.524	0.4
comGC/cglC	Streptococcus pneumoniae Rx1	44.681	89.524	0.4
comGC/cglC	Streptococcus pneumoniae D39	44.681	89.524	0.4
comGC/cglC	Streptococcus pneumoniae R6	44.681	89.524	0.4
comYC	Streptococcus mutans UA159	47.674	81.905	0.39
comYC	Streptococcus mutans UA140	47.674	81.905	0.39
comYC	Streptococcus gordonii str. Challis substr. CH1	46.512	81.905	0.381
comGC	Lactococcus lactis subsp. cremoris KW2	47.561	78.095	0.371
comGC/cglC	Streptococcus mitis NCTC 12261	50	74.286	0.371
comYC	Streptococcus suis isolate S10	48.718	74.286	0.362
comGC	Bacillus subtilis subsp. subtilis str. 168	41.758	86.667	0.362