Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   HWI55_RS00290 Genome accession   NZ_CP064485
Coordinates   64187..65815 (-) Length   542 a.a.
NCBI ID   WP_407567791.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain UMCG382     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Genomic Context

Location: 59187..70815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWI55_RS00250 (HWI55_00245) galU 59730..60495 (-) 766 Protein_47 UTP--glucose-1-phosphate uridylyltransferase GalU -
  HWI55_RS00255 (HWI55_00250) - 60912..61043 (-) 132 WP_257473760.1 hypothetical protein -
  HWI55_RS00260 - 61169..61284 (+) 116 Protein_49 type I restriction enzyme endonuclease domain-containing protein -
  HWI55_RS00265 (HWI55_00255) - 61340..61837 (-) 498 WP_012086596.1 hypothetical protein -
  HWI55_RS00270 (HWI55_00260) - 61844..62122 (-) 279 WP_012086594.1 hypothetical protein -
  HWI55_RS00275 (HWI55_00265) - 62420..62923 (-) 504 WP_012086592.1 DUF1643 domain-containing protein -
  HWI55_RS00280 (HWI55_00270) - 62938..63249 (-) 312 WP_000700851.1 DUF960 family protein -
  HWI55_RS00285 (HWI55_00275) - 63336..63686 (-) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  HWI55_RS00290 (HWI55_00280) ccrB 64187..65815 (-) 1629 WP_407567791.1 cassette chromosome recombinase CcrB Machinery gene
  HWI55_RS00295 (HWI55_00285) ccrA 65812..67173 (-) 1362 WP_001631036.1 cassette chromosome recombinase CcrA Machinery gene
  HWI55_RS00300 (HWI55_00290) - 67360..67989 (-) 630 Protein_57 hypothetical protein -
  HWI55_RS00305 (HWI55_00295) - 67998..68336 (+) 339 Protein_58 recombinase family protein -
  HWI55_RS00310 (HWI55_00300) - 68448..68807 (-) 360 WP_001631039.1 hypothetical protein -
  HWI55_RS00315 (HWI55_00305) - 69014..69340 (+) 327 WP_000391495.1 metalloregulator ArsR/SmtB family transcription factor -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62421.66 Da        Isoelectric Point: 9.5131

>NTDB_id=502292 HWI55_RS00290 WP_407567791.1 64187..65815(-) (ccrB) [Staphylococcus epidermidis strain UMCG382]
MKQLKKKRIGLYARVSTEMQTDGYSIQGQLNQLTEYCQFQGYEVVNEYTDRGISGKTMQRPELQRMLKDANEGKLDCIMV
YKTNRLARNTSDLLNIVEELYKINVEFFSLTEKIEIASSTGKLMLQILASFAEFERNTIVENVYNGQRQRAIEGYYQGNL
PLGYDKVPDSKKELMINQHEANIVKYIFDSYAKGHGYCKIANALNHKGYVTKKGKPFSISSITYIISNPFYIGKIQFAKY
RHWSDKRRKGLNEEPIIADGKHAPIIDRNLWDKVQFKRQESRKKPQVHGKGTNLLTGIVKCPKCGAAMAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVLEKYVMDQILEIIKSKKVLKQLVEKVNEKSQIDVSSLNHDIAYKQSQCEE
IKAKMHTLTKTIEDSPDLDSVLKPTILSYQDELNQINNQIYQLEQDKQAEAPHYDADMIANVLQAIFKDIDKLEKSQLKS
LYLTIIDRIDIRKDEHHKKQFYVTLKLNNDIIKQLFNNHPLDEVLPSTSSLFLPQTLYITIE

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=502292 HWI55_RS00290 WP_407567791.1 64187..65815(-) (ccrB) [Staphylococcus epidermidis strain UMCG382]
ATGAAACAACTCAAAAAGAAACGTATTGGATTATATGCACGTGTATCGACTGAAATGCAAACGGATGGTTACAGTATTCA
AGGTCAATTGAATCAACTTACAGAGTATTGTCAATTTCAAGGCTATGAAGTCGTCAATGAATACACCGATCGTGGTATAT
CAGGTAAAACAATGCAACGTCCAGAATTACAACGTATGTTAAAAGATGCCAACGAAGGTAAATTAGATTGTATTATGGTC
TACAAAACAAATCGTTTAGCTAGAAATACCTCAGATTTGTTAAATATTGTCGAGGAATTGTATAAGATTAATGTCGAATT
TTTTAGTCTAACTGAAAAAATAGAAATTGCCAGTTCAACAGGTAAATTGATGCTCCAAATTTTAGCCAGCTTCGCAGAAT
TTGAACGTAATACGATTGTAGAGAATGTCTACAATGGCCAAAGACAACGTGCTATTGAAGGTTATTATCAAGGTAATTTA
CCTCTAGGCTACGATAAAGTACCTGACAGTAAAAAAGAGCTCATGATCAATCAACATGAAGCGAATATTGTTAAATATAT
TTTTGATTCATACGCTAAAGGTCATGGTTATTGTAAGATTGCGAACGCATTGAATCATAAAGGTTATGTGACTAAGAAAG
GGAAACCTTTTAGTATTTCGTCCATTACCTACATCATCTCAAACCCTTTTTACATTGGAAAGATACAGTTTGCGAAGTAT
AGACACTGGAGCGATAAAAGACGAAAAGGACTCAATGAGGAACCGATTATCGCTGATGGTAAACATGCGCCTATTATTGA
TAGAAACCTATGGGATAAAGTACAGTTTAAACGTCAAGAGAGTCGCAAGAAACCACAAGTTCACGGCAAAGGAACAAACC
TACTGACTGGGATTGTAAAATGTCCGAAATGTGGTGCAGCAATGGCGGCAAGTAATACAACTAATACATTAAAAGATGGC
ACTAAGAAAAGAATCAGATATTACTCATGTAGCAATTTTAGAAATAAAGGTTCAAAAGTTTGTTCTGCCAATAGCGTTAG
AGCAGATGTACTAGAAAAATATGTTATGGATCAGATATTGGAAATTATCAAAAGCAAAAAGGTATTGAAGCAATTGGTTG
AAAAGGTAAATGAAAAAAGTCAAATAGACGTCTCTTCTTTGAACCATGATATTGCCTATAAACAGTCACAATGTGAAGAA
ATAAAAGCAAAAATGCATACATTAACGAAAACTATTGAAGACTCACCTGACTTAGATAGCGTATTAAAACCAACAATACT
TAGCTACCAAGATGAATTGAATCAAATAAATAATCAAATCTATCAACTAGAACAAGATAAACAAGCAGAAGCTCCACATT
ATGATGCTGATATGATTGCGAATGTACTACAAGCAATATTCAAAGATATAGACAAATTAGAGAAATCTCAGTTGAAATCA
CTATATCTAACAATCATCGATCGCATTGACATAAGAAAAGATGAGCATCATAAGAAGCAATTTTATGTTACGCTCAAGTT
AAATAATGATATAATCAAACAACTATTTAATAACCATCCACTCGACGAAGTGCTCCCTAGCACTTCGTCTTTATTTTTGC
CACAAACTTTATATATAACTATTGAATAA

Domains

Predicted by InterProScan.

Ogr/Delta-like zinc finger (Ogr_Delta)

(300-355)

Resolvase, N terminal domain (Resolvase)

(11-154)

Recombinase (Recombinase)

(179-280)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

72.509

100

0.725