Detailed information NTG0502006

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HWI64_RS04475
• Genome accession: NZ_CP064456
• Coordinates: 964321..965367 (+)
• Length: 348 a.a.
• NCBI ID: WP_002486322.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain UMCG392
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 959321..970367

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HWI64_RS04450 (HWI64_04420)	isaB	960462..960998 (+)	537	WP_001830372.1	immunodominant staphylococcal antigen IsaB family protein	-
HWI64_RS04455 (HWI64_04425)	-	961149..962135 (-)	987	WP_002457091.1	aromatic acid exporter family protein	-
HWI64_RS04460 (HWI64_04430)	map	962309..963064 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
HWI64_RS04465 (HWI64_04435)	-	963222..963608 (+)	387	WP_001830382.1	hypothetical protein	-
HWI64_RS04470 (HWI64_04440)	liaF	963623..964324 (+)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
HWI64_RS04475 (HWI64_04445)	vraS	964321..965367 (+)	1047	WP_002486322.1	sensor histidine kinase	Regulator
HWI64_RS04480 (HWI64_04450)	vraR	965357..965986 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
HWI64_RS04485 (HWI64_04455)	-	966043..967221 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
HWI64_RS04490 (HWI64_04460)	-	967628..967912 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
HWI64_RS04495 (HWI64_04465)	-	967920..968384 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
HWI64_RS04500 (HWI64_04470)	-	968525..968740 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
HWI64_RS04505 (HWI64_04475)	-	968742..969983 (+)	1242	WP_002457094.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40039.46 Da
• Isoelectric Point: 5.8512

>NTDB_id=502006 HWI64_RS04475 WP_002486322.1 964321..965367(+) (vraS) [Staphylococcus epidermidis strain UMCG392]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVSIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=502006 HWI64_RS04475 WP_002486322.1 964321..965367(+) (vraS) [Staphylococcus epidermidis strain UMCG392]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAGTATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.733	98.851	0.917