Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   IUJ40_RS03545 Genome accession   NZ_CP064389
Coordinates   711279..711995 (-) Length   238 a.a.
NCBI ID   WP_064139150.1    Uniprot ID   -
Organism   Staphylococcus aureus strain PartE-Saureus-RM8376     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 706279..716995
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IUJ40_RS03525 (IUJ40_03525) - 707373..708323 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  IUJ40_RS03530 (IUJ40_03530) - 708472..709956 (+) 1485 WP_023487214.1 sucrose-6-phosphate hydrolase -
  IUJ40_RS03535 (IUJ40_03535) - 709953..710912 (+) 960 WP_001253312.1 carbohydrate kinase -
  IUJ40_RS03540 (IUJ40_03540) - 711100..711207 (-) 108 WP_033841749.1 hypothetical protein -
  IUJ40_RS03545 (IUJ40_03545) agrA 711279..711995 (-) 717 WP_064139150.1 quorum-sensing response regulator AgrA Regulator
  IUJ40_RS03550 (IUJ40_03550) agrC 712014..713306 (-) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  IUJ40_RS03555 (IUJ40_03555) agrD 713331..713471 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  IUJ40_RS03560 (IUJ40_03560) agrB 713468..714037 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  IUJ40_RS03565 hld 714327..714407 (+) 81 WP_000046022.1 delta-hemolysin -
  IUJ40_RS03570 (IUJ40_03570) - 715004..715789 (-) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  IUJ40_RS03575 (IUJ40_03575) - 716150..716776 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27965.94 Da        Isoelectric Point: 6.0935

>NTDB_id=501566 IUJ40_RS03545 WP_064139150.1 711279..711995(-) (agrA) [Staphylococcus aureus strain PartE-Saureus-RM8376]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRYHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=501566 IUJ40_RS03545 WP_064139150.1 711279..711995(-) (agrA) [Staphylococcus aureus strain PartE-Saureus-RM8376]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATATCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996