Detailed information NTG0501562

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IUJ40_RS00370
• Genome accession: NZ_CP064389
• Coordinates: 85668..86555 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain PartE-Saureus-RM8376
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 80668..91555

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IUJ40_RS00340 (IUJ40_00345)	-	81400..82161 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
IUJ40_RS00345 (IUJ40_00350)	-	82406..82861 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IUJ40_RS15135	-	82983..83084 (+)	102	WP_000731972.1	SE2200 family small protein	-
IUJ40_RS00355 (IUJ40_00360)	-	83144..84568 (-)	1425	WP_000953744.1	alkaline phosphatase	-
IUJ40_RS00360 (IUJ40_00365)	-	84766..84966 (+)	201	WP_000604728.1	hypothetical protein	-
IUJ40_RS00365 (IUJ40_00370)	braR	84992..85657 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IUJ40_RS00370 (IUJ40_00375)	braS	85668..86555 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IUJ40_RS00375 (IUJ40_00380)	-	86663..87418 (+)	756	WP_033841467.1	ABC transporter ATP-binding protein	-
IUJ40_RS00380 (IUJ40_00385)	-	87415..89415 (+)	2001	WP_000776751.1	ABC transporter permease	-
IUJ40_RS00385 (IUJ40_00390)	-	90074..90187 (+)	114	WP_011447078.1	hypothetical protein	-
IUJ40_RS00390 (IUJ40_00395)	-	90569..90829 (+)	261	WP_001789910.1	hypothetical protein	-
IUJ40_RS00395 (IUJ40_00400)	-	90839..91336 (+)	498	WP_001065268.1	glutathione peroxidase	-
IUJ40_RS00400 (IUJ40_00405)	-	91444..91536 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=501562 IUJ40_RS00370 WP_000143419.1 85668..86555(+) (braS) [Staphylococcus aureus strain PartE-Saureus-RM8376]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=501562 IUJ40_RS00370 WP_000143419.1 85668..86555(+) (braS) [Staphylococcus aureus strain PartE-Saureus-RM8376]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997