Detailed information NTG0501123

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IUJ41_RS05630
• Genome accession: NZ_CP064365
• Coordinates: 1140660..1141547 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain PartF-Saureus-RM8376
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1135660..1146547

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IUJ41_RS05600 (IUJ41_05575)	-	1136392..1137153 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
IUJ41_RS05605 (IUJ41_05580)	-	1137398..1137853 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IUJ41_RS13830	-	1137975..1138076 (+)	102	WP_000731972.1	SE2200 family small protein	-
IUJ41_RS05615 (IUJ41_05590)	-	1138136..1139560 (-)	1425	WP_000953744.1	alkaline phosphatase	-
IUJ41_RS05620 (IUJ41_05595)	-	1139758..1139958 (+)	201	WP_000604728.1	hypothetical protein	-
IUJ41_RS05625 (IUJ41_05600)	braR	1139984..1140649 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IUJ41_RS05630 (IUJ41_05605)	braS	1140660..1141547 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IUJ41_RS05635 (IUJ41_05610)	-	1141655..1142410 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IUJ41_RS05640 (IUJ41_05615)	-	1142407..1144407 (+)	2001	WP_000776751.1	ABC transporter permease	-
IUJ41_RS05645 (IUJ41_05620)	-	1145066..1145179 (+)	114	WP_011447078.1	hypothetical protein	-
IUJ41_RS05650 (IUJ41_05625)	-	1145561..1145821 (+)	261	WP_001789910.1	hypothetical protein	-
IUJ41_RS05655 (IUJ41_05630)	-	1145831..1146328 (+)	498	WP_001065268.1	glutathione peroxidase	-
IUJ41_RS05660 (IUJ41_05635)	-	1146436..1146528 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=501123 IUJ41_RS05630 WP_000143419.1 1140660..1141547(+) (braS) [Staphylococcus aureus strain PartF-Saureus-RM8376]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=501123 IUJ41_RS05630 WP_000143419.1 1140660..1141547(+) (braS) [Staphylococcus aureus strain PartF-Saureus-RM8376]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997