Detailed information NTG0501065

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: IUJ46_RS03775
• Genome accession: NZ_CP064364
• Coordinates: 729813..731123 (-)
• Length: 436 a.a.
• NCBI ID: WP_010922354.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain PartK-Spyogenes-RM8376
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 724813..736123

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IUJ46_RS03750 (IUJ46_03735)	-	725417..726469 (-)	1053	WP_002989701.1	BMP family protein	-
IUJ46_RS03755 (IUJ46_03740)	-	726563..726952 (-)	390	WP_011285547.1	cytidine deaminase	-
IUJ46_RS03760 (IUJ46_03745)	-	727605..728198 (-)	594	WP_010922352.1	class I SAM-dependent methyltransferase	-
IUJ46_RS03765 (IUJ46_03750)	coaA	728466..729386 (+)	921	WP_010922353.1	type I pantothenate kinase	-
IUJ46_RS03770 (IUJ46_03755)	rpsT	729440..729688 (+)	249	WP_009881183.1	30S ribosomal protein S20	-
IUJ46_RS03775 (IUJ46_03760)	ciaH	729813..731123 (-)	1311	WP_010922354.1	HAMP domain-containing sensor histidine kinase	Regulator
IUJ46_RS03780 (IUJ46_03765)	ciaR	731116..731790 (-)	675	WP_010922355.1	response regulator transcription factor	Regulator
IUJ46_RS03785 (IUJ46_03770)	-	732136..734673 (-)	2538	WP_010922356.1	M1 family metallopeptidase	-
IUJ46_RS03790 (IUJ46_03775)	phoU	734878..735531 (-)	654	WP_002984514.1	phosphate signaling complex protein PhoU	-

Sequence

Protein

• Length: 436 a.a.
• Molecular weight: 50013.52 Da
• Isoelectric Point: 9.0831

>NTDB_id=501065 IUJ46_RS03775 WP_010922354.1 729813..731123(-) (ciaH) [Streptococcus pyogenes strain PartK-Spyogenes-RM8376]
MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYSSVDSSLVSVSNNASSYANRTMARISSFYFDTENNII
KALPDSDSSKLLGTPAANTDIILFSANGTILNAFDAFSNYQNFHLDKRRLGSIETTSLMNFYGQEEKYHTITVGVHIKNY
PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQN
QVNRSLRMDKALLKQLITILFDNAIKYTDKNGIIEIIVKTTDKNLLISVIDNGPGITDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVMSLKGNITVKDNDPKGSIFEVKL

Nucleotide

• Length: 1311 bp

>NTDB_id=501065 IUJ46_RS03775 WP_010922354.1 729813..731123(-) (ciaH) [Streptococcus pyogenes strain PartK-Spyogenes-RM8376]
ATGAATAAATTAAAAAAAGAGATTTTATCAGATAACTATAACCACTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTCATTATGACTATTATTATCTTACAGATTATGCGGTTTGGCGTTTATTCGTCAGTTGACAGTAGTTTAGTTTCTGTTA
GTAATAATGCAAGTAGCTATGCTAATCGTACGATGGCTAGAATATCTTCTTTTTACTTTGATACTGAAAATAACATTATT
AAGGCGCTGCCTGATTCAGATAGTTCTAAGTTATTAGGAACGCCTGCAGCTAATACAGATATCATTTTGTTTAGTGCTAA
TGGAACAATTTTAAATGCTTTTGATGCGTTTTCTAACTATCAAAATTTTCATTTAGATAAACGCCGGTTGGGGAGTATTG
AAACCACCAGTTTAATGAATTTTTATGGACAAGAAGAAAAATACCATACGATAACTGTAGGGGTTCATATCAAAAATTAT
CCTGCAGTTGCCTATATGATGGCAGTAGTAAATGTGGAACAATTAGACCGCGCTAATGAACGTTATGAGCGCATTATTAT
TATAGTTATGAGTGTTTTTTGGCTAATTTCTATTTTAGCAAGTATTTATTTAGCCAAGTGGAGCAGAAAACCTATTTTAG
AAAGCTATGAAAAACAAAAAATGTTTGTTGAAAATGCTAGTCATGAATTAAGGACCCCTTTGGCGGTCTTACAGAATCGT
CTGGAATCGCTTTTTCGTAAGCCCAACGAAACGATATTAGAAAATAGTGAGCATCTCGCTTCTAGTTTAGACGAGGTTCG
CAACATGCGCATCTTAACAACTAATTTATTAAATTTAGCAAGACGAGATGATGGCATTAATCCACAGTGGACTCATTTAG
ATACAGATTTTTTTAATGCTATTTTTGAGAATTATGAACTAGTTGCTAAAGAATATGGAAAAATATTTTATTTTCAGAAC
CAAGTCAATAGATCGTTAAGAATGGATAAGGCTTTACTAAAACAATTAATAACGATTTTATTTGACAATGCTATTAAATA
TACAGATAAAAATGGTATTATTGAAATTATAGTGAAAACAACGGACAAAAATTTATTAATTTCTGTTATTGATAATGGTC
CAGGGATAACAGATGAAGAAAAGAAAAAGATTTTTGATCGTTTTTATCGAGTTGACAAAGCTAGAACACGGCAAACAGGT
GGATTTGGCTTGGGGTTGGCTTTAGCTCAGCAAATCGTGATGTCTTTAAAAGGAAATATTACAGTAAAGGATAATGATCC
TAAAGGTAGTATTTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (329-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (220-285)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	57.895	100	0.58
ciaH	Streptococcus pneumoniae Rx1	51.37	100	0.516
ciaH	Streptococcus pneumoniae D39	51.37	100	0.516
ciaH	Streptococcus pneumoniae R6	51.37	100	0.516
ciaH	Streptococcus pneumoniae TIGR4	51.37	100	0.516