Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   IUJ42_RS00205 Genome accession   NZ_CP064359
Coordinates   39165..40793 (-) Length   542 a.a.
NCBI ID   WP_011082541.1    Uniprot ID   Q8CQJ0
Organism   Staphylococcus epidermidis strain PartG-Sepidermidis-RM8376     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 23035..57963 39165..40793 within 0


Gene organization within MGE regions


Location: 23035..57963
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IUJ42_RS00120 (IUJ42_00120) ccrA 24664..26013 (-) 1350 WP_011082535.1 recombinase family protein Machinery gene
  IUJ42_RS00125 (IUJ42_00125) - 26247..28040 (-) 1794 WP_011082536.1 DUF927 domain-containing protein -
  IUJ42_RS00130 (IUJ42_00130) - 28040..28336 (-) 297 WP_011082537.1 single-stranded DNA-binding protein -
  IUJ42_RS00135 (IUJ42_00135) - 28529..29575 (-) 1047 WP_001042023.1 hypothetical protein -
  IUJ42_RS00140 (IUJ42_00140) - 30030..31184 (+) 1155 WP_011082538.1 ATP-binding protein -
  IUJ42_RS00145 (IUJ42_00145) - 31214..32014 (+) 801 WP_000749912.1 abortive infection family protein -
  IUJ42_RS00150 (IUJ42_00150) - 32199..32342 (+) 144 WP_001631028.1 restriction endonuclease subunit R -
  IUJ42_RS00155 (IUJ42_00155) - 32335..33537 (+) 1203 WP_001631029.1 restriction endonuclease subunit S -
  IUJ42_RS00160 (IUJ42_00160) - 33582..33798 (-) 217 Protein_29 IS5/IS1182 family transposase -
  IUJ42_RS00165 (IUJ42_00165) - 33860..34357 (-) 498 WP_001631030.1 GNAT family N-acetyltransferase -
  IUJ42_RS00170 (IUJ42_00175) - 35029..35439 (-) 411 WP_001631031.1 DUF2871 domain-containing protein -
  IUJ42_RS00175 (IUJ42_00180) - 35602..35822 (-) 221 Protein_32 hypothetical protein -
  IUJ42_RS00180 (IUJ42_00185) - 35837..36076 (-) 240 Protein_33 DUF1643 domain-containing protein -
  IUJ42_RS00185 (IUJ42_00190) - 36184..37383 (-) 1200 WP_071813246.1 IS110-like element ISSep2 family transposase -
  IUJ42_RS00190 (IUJ42_00195) - 37634..37900 (-) 267 Protein_35 DUF1643 domain-containing protein -
  IUJ42_RS00195 (IUJ42_00200) - 37916..38227 (-) 312 WP_002501910.1 DUF960 family protein -
  IUJ42_RS00200 (IUJ42_00205) - 38314..38664 (-) 351 WP_002485722.1 SAUGI family uracil-DNA glycosylase inhibitor -
  IUJ42_RS00205 (IUJ42_00210) ccrB 39165..40793 (-) 1629 WP_011082541.1 recombinase family protein Machinery gene
  IUJ42_RS00210 (IUJ42_00215) ccrA 40790..42151 (-) 1362 WP_001631036.1 recombinase family protein Machinery gene
  IUJ42_RS00215 (IUJ42_00220) - 42338..42967 (-) 630 Protein_40 hypothetical protein -
  IUJ42_RS00220 (IUJ42_00225) - 42976..43314 (+) 339 Protein_41 recombinase family protein -
  IUJ42_RS00225 (IUJ42_00230) - 43426..43785 (-) 360 WP_001631039.1 hypothetical protein -
  IUJ42_RS00230 (IUJ42_00235) - 43992..44318 (+) 327 WP_000391495.1 metalloregulator ArsR/SmtB family transcription factor -
  IUJ42_RS00235 (IUJ42_00240) - 44648..46573 (+) 1926 WP_002485723.1 heavy metal translocating P-type ATPase -
  IUJ42_RS00240 (IUJ42_00245) - 47696..48646 (-) 951 Protein_45 transposase -
  IUJ42_RS00245 (IUJ42_00250) - 48767..49336 (+) 570 WP_002470562.1 hypothetical protein -
  IUJ42_RS00250 (IUJ42_00255) - 49381..50538 (+) 1158 WP_002485721.1 hypothetical protein -
  IUJ42_RS00255 (IUJ42_00260) - 50721..50945 (+) 225 WP_070866987.1 hypothetical protein -
  IUJ42_RS00260 (IUJ42_00265) - 50970..51644 (+) 675 WP_011082546.1 IS6-like element IS257 family transposase -
  IUJ42_RS00265 (IUJ42_00270) lspA 51672..52049 (-) 378 WP_011082547.1 signal peptidase II -
  IUJ42_RS00270 (IUJ42_00275) - 52284..52685 (+) 402 WP_002485756.1 metalloregulator ArsR/SmtB family transcription factor -
  IUJ42_RS00275 (IUJ42_00280) - 53011..53706 (+) 696 WP_225793074.1 ZIP family metal transporter -
  IUJ42_RS00280 (IUJ42_00285) - 53963..56371 (+) 2409 WP_002485759.1 heavy metal translocating P-type ATPase -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62532.74 Da        Isoelectric Point: 9.5610

>NTDB_id=501016 IUJ42_RS00205 WP_011082541.1 39165..40793(-) (ccrB) [Staphylococcus epidermidis strain PartG-Sepidermidis-RM8376]
MKQLKKKRIGLYARVSTEMQTDGYSIQGQLNQLTEYCQFQGYEVVNEYTDRGISGKTMQRPELQRMLKDANEGKLDCIMV
YKTNRLARNTSDLLNIVEELYKINVEFFSLTEKIEIASSTGKLMLQILASFAEFERNTIVENVYNGQRQRAIEGYYQGNL
PLGYDKVPDSKKELMINQHEANIVKYIFDSYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYIISNPFYIGKIQFAKY
RHWSDKRRKGLNEEPIIADGKHAPIIDRNLWDKVQFKRQESRKKPQVHGKGTNLLTGIVKCPKCGAAMEASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVLEKYVMDQILEIIKSKKVLKQLVEKVNEKSQIDVSSLNHDIAYKQSQCEE
IKAKMHTLTKTIEDSPDLDSVLKPTILSYQDELNQINNQIYQLEQDKQAEAPHYDADMIANVLQAIFKDIDKLEKSQLKS
LYLTIIDRIDIRKDEHHKKQFYVTLKLNNDIIKQLFNNHPLDEVLPSTSSLFLPQTLYITIE

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=501016 IUJ42_RS00205 WP_011082541.1 39165..40793(-) (ccrB) [Staphylococcus epidermidis strain PartG-Sepidermidis-RM8376]
ATGAAACAACTCAAAAAGAAACGTATTGGATTATATGCACGTGTATCGACTGAAATGCAAACGGATGGTTACAGTATTCA
AGGTCAATTGAATCAACTTACAGAGTATTGTCAATTTCAAGGCTATGAAGTCGTCAATGAATACACCGATCGTGGTATAT
CAGGTAAAACAATGCAACGTCCAGAATTACAACGTATGTTAAAAGATGCCAACGAAGGTAAATTAGATTGTATTATGGTC
TACAAAACAAATCGTTTAGCTAGAAATACCTCAGATTTGTTAAATATTGTCGAGGAATTGTATAAGATTAATGTCGAATT
TTTTAGTCTAACTGAAAAAATAGAAATTGCCAGTTCAACAGGTAAATTGATGCTCCAAATTTTAGCCAGCTTCGCAGAAT
TTGAACGTAATACGATTGTAGAGAATGTCTACAATGGCCAAAGACAACGTGCTATTGAAGGTTATTATCAAGGTAATTTA
CCTCTAGGCTACGATAAAGTACCTGACAGTAAAAAAGAGCTCATGATCAATCAACATGAAGCGAATATTGTTAAATATAT
TTTTGATTCATACGCTAAAGGTCATGGTTATCGTAAGATTGCGAACGCATTGAATCATAAAGGTTATGTGACTAAGAAAG
GGAAACCTTTTAGTATTTCGTCCATTACCTACATCATCTCAAACCCTTTTTACATTGGAAAGATACAGTTTGCGAAGTAT
AGACACTGGAGCGATAAAAGACGAAAAGGACTCAATGAGGAACCGATTATCGCTGATGGTAAACATGCGCCTATTATTGA
TAGAAACCTATGGGATAAAGTACAGTTTAAACGTCAAGAGAGTCGCAAGAAACCACAAGTTCACGGCAAAGGAACAAACC
TACTGACTGGGATTGTAAAATGTCCGAAATGTGGTGCAGCAATGGAGGCAAGTAATACAACTAATACATTAAAAGATGGC
ACTAAGAAAAGAATCAGATATTACTCATGTAGCAATTTTAGAAATAAAGGTTCAAAAGTTTGTTCTGCCAATAGCGTTAG
AGCAGATGTACTAGAAAAATATGTTATGGATCAGATATTGGAAATTATCAAAAGCAAAAAGGTATTGAAGCAATTGGTTG
AAAAGGTAAATGAAAAAAGTCAAATAGACGTCTCTTCTTTGAACCATGATATTGCCTATAAACAGTCACAATGTGAAGAA
ATAAAAGCAAAAATGCATACATTAACGAAAACTATTGAAGACTCACCTGACTTAGATAGCGTATTAAAACCAACAATACT
TAGCTACCAAGATGAATTGAATCAAATAAATAATCAAATCTATCAACTAGAACAAGATAAACAAGCAGAAGCTCCACATT
ATGATGCTGATATGATTGCGAATGTACTACAAGCAATATTCAAAGATATAGACAAATTAGAGAAATCTCAGTTGAAATCA
CTATATCTAACAATCATCGATCGCATTGACATAAGAAAAGATGAGCATCATAAGAAGCAATTTTATGTTACGCTCAAGTT
AAATAATGATATAATCAAACAACTATTTAATAACCATCCACTCGACGAAGTGCTCCCTAGCACTTCGTCTTTATTTTTGC
CACAAACTTTATATATAACTATTGAATAA

Domains

Predicted by InterproScan.

Ogr/Delta-like zinc finger (Ogr_Delta)

(300-355)

Resolvase, N terminal domain (Resolvase)

(11-154)

Recombinase (Recombinase)

(179-280)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8CQJ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

72.509

100

0.725