Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   KKZ08_RS09300 Genome accession   NZ_CP075691
Coordinates   2057837..2060932 (-) Length   1031 a.a.
NCBI ID   WP_223773992.1    Uniprot ID   -
Organism   Streptomyces sp. 135     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2052837..2065932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KKZ08_RS09275 - 2053201..2053860 (-) 660 WP_223773987.1 papain-like cysteine protease family protein -
  KKZ08_RS09280 - 2054086..2055171 (+) 1086 WP_223773988.1 hypothetical protein -
  KKZ08_RS09285 - 2055185..2055613 (-) 429 WP_223773989.1 Rieske (2Fe-2S) protein -
  KKZ08_RS09290 - 2055807..2056739 (+) 933 WP_223773990.1 carbohydrate kinase -
  KKZ08_RS09295 - 2056890..2057663 (-) 774 WP_223773991.1 crotonase/enoyl-CoA hydratase family protein -
  KKZ08_RS09300 uvrA 2057837..2060932 (-) 3096 WP_223773992.1 excinuclease ABC subunit UvrA Machinery gene
  KKZ08_RS09305 - 2061184..2061876 (+) 693 WP_223773993.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  KKZ08_RS09310 - 2061887..2062543 (+) 657 WP_223773994.1 MBL fold metallo-hydrolase -
  KKZ08_RS09315 aroQ 2062577..2063050 (-) 474 WP_223773995.1 type II 3-dehydroquinate dehydratase -
  KKZ08_RS09320 - 2063130..2064176 (+) 1047 WP_223778972.1 S66 peptidase family protein -
  KKZ08_RS09325 - 2064239..2065525 (+) 1287 WP_223773996.1 MFS transporter -

Sequence

Protein


Download         Length: 1031 a.a.        Molecular weight: 112570.02 Da        Isoelectric Point: 8.1037

>NTDB_id=499652 KKZ08_RS09300 WP_223773992.1 2057837..2060932(-) (uvrA) [Streptomyces sp. 135]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECGRPITRQSPQAIVDKVLELPEGSRFQVLSPLVRERK
GEFVDLFADLQTKGYSRARVDGQTIQLSEPPTLKKQEKHTIEVVVDRLTVKDSAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCPYDDLSFEELEPRSFSFNSPFGACPDCTGIGTRMEVDPELIVPDEDKSLDEGAIHPWSHGHTK
DYFARLVNALSDALGFATDMPWAGLPQRAKKALLYGHKTQIEVRYRNRYGRERVYTTAFEGAVPFVKRRHSEAESDASRE
RFEGYMREVPCPTCEGTRLKPIVLAVTVMGKSIAEVSAMSISDCADFLAELRLGARDKKIAERVLKEVNERLRFLVDVGL
DYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVAD
WVVDIGPGAGEHGGKVVHSGSMKELLDNDKSITGQYLSGKKAIPVPDVRRPADPARRLTVHGARENNLQDIDVSFPLGVL
TAVTGVSGSGKSTLVNDILYTHLARELNGARSVPGRHTRVEGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHVRKLFA
ETTEAKVRGYLPGRFSFNVKGGRCENCSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLDVHYKGKSIAEVLDMPIEEA
LGFFEAVPAIARHLKTLTDVGLGYVRLGQSAPTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDISKLITVLS
GLVDKGNTVIVIEHNLDVIKTADWVVDMGPEGGSGGGLVVAEGTPEEVAGVSTSHTGKFLREIISADRISDALPSQGRKP
AKKATAKKATAKRAVAASATATKKTATVRTGTAAADKPTATAKKAAATTKKTAAATKKAAAKKTATRARKA

Nucleotide


Download         Length: 3096 bp        

>NTDB_id=499652 KKZ08_RS09300 WP_223773992.1 2057837..2060932(-) (uvrA) [Streptomyces sp. 135]
GTGGCCGACCGTCTCATCGTCCGTGGCGCGCGCGAGCACAATCTCAAGAACGTCTCGCTCGACCTCCCGCGTGACTCCCT
CATCGTGTTCACCGGACTCTCCGGGTCGGGCAAGTCCTCGCTCGCGTTCGACACGATCTTCGCCGAGGGCCAGCGGCGGT
ACGTCGAGTCGCTTTCCTCGTACGCCCGGCAGTTCCTCGGCCAGATGGACAAGCCCGACGTCGACTTCATCGAGGGCCTC
TCCCCGGCGGTCTCCATCGACCAGAAGTCGACCTCGCGCAACCCACGCTCGACGGTCGGCACCATCACCGAGGTCTACGA
CTACCTGCGCCTGCTCTTCGCGCGCATCGGCAAGCCGCACTGTCCCGAGTGCGGCCGCCCCATTACCCGGCAGTCGCCGC
AGGCCATCGTCGACAAGGTCCTGGAGTTGCCCGAGGGCAGCCGCTTCCAGGTCCTGTCCCCGCTGGTGCGCGAGCGCAAG
GGCGAGTTCGTCGACCTCTTCGCCGACCTCCAGACCAAGGGGTACTCCCGCGCGCGGGTCGACGGACAGACGATCCAGCT
CTCCGAGCCGCCCACGCTCAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCGTCGACCGCCTCACGGTGAAGGACTCCG
CCAAGCGCCGCCTGACCGACTCCGTGGAGACCGCCCTCGGCCTCTCCGGCGGCATGGTCGTGCTCGACTTCGTCGACCTC
CCCGAGGACGACCCCGAGCGCGAGCGCATGTACTCGGAGCACCTCTACTGCCCGTACGACGACCTGTCCTTCGAGGAGCT
GGAGCCCCGCTCCTTCTCCTTCAACTCGCCCTTCGGCGCCTGCCCGGACTGCACGGGTATCGGTACGCGCATGGAGGTCG
ACCCCGAGCTGATCGTCCCGGACGAGGACAAGTCGCTCGACGAGGGCGCCATCCACCCCTGGTCGCACGGCCACACCAAG
GACTACTTCGCCCGCTTGGTGAACGCGCTCTCCGACGCCCTCGGCTTCGCCACCGACATGCCCTGGGCCGGGCTTCCGCA
GCGCGCCAAGAAGGCCCTGCTGTACGGCCACAAGACGCAGATCGAGGTGCGCTACCGCAACCGCTACGGCCGCGAGCGGG
TCTACACCACCGCCTTCGAAGGCGCCGTGCCCTTCGTCAAGCGCCGGCACAGCGAGGCCGAGAGCGACGCCAGTCGCGAG
CGCTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCCACCTGTGAGGGCACGCGCCTCAAGCCGATCGTCCTGGCCGTCAC
GGTCATGGGGAAGTCCATCGCCGAGGTCTCCGCGATGTCCATCAGCGACTGCGCGGACTTCCTCGCCGAGCTGAGGCTGG
GCGCCCGCGACAAGAAGATCGCCGAGCGCGTCCTCAAGGAGGTCAACGAAAGGCTGCGCTTCCTGGTCGACGTCGGCCTG
GACTACCTCTCGCTGAACCGCGCGGCGGGCACCCTCTCCGGAGGCGAGGCCCAGCGCATCCGCCTCGCCACCCAGATCGG
CTCCGGCCTCGTCGGCGTGCTCTACGTCCTGGACGAGCCGTCCATCGGCCTCCACCAGCGCGACAACCACCGGCTCATCG
AGACCCTCGTACGCCTGCGCGACATGGGCAACACGCTCATCGTCGTCGAGCACGACGAGGACACGATCAAGGTCGCCGAC
TGGGTCGTCGACATCGGCCCCGGCGCGGGCGAGCACGGCGGCAAGGTCGTGCACAGCGGCTCCATGAAGGAGCTGCTGGA
CAACGACAAGTCGATCACCGGGCAGTACCTCTCGGGCAAGAAGGCCATCCCGGTCCCTGACGTGCGCCGACCCGCCGACC
CGGCGCGCCGGCTCACGGTCCACGGCGCCCGGGAGAACAACCTCCAGGACATCGACGTCTCCTTCCCGCTCGGCGTCCTC
ACGGCCGTCACCGGCGTCTCGGGGTCCGGCAAGTCGACGCTGGTCAACGACATCCTCTACACGCACCTGGCCAGGGAGCT
GAACGGCGCCCGTTCCGTCCCGGGCCGCCACACGCGCGTGGAGGGCGACGACCTCGTCGACAAGGTCGTACACGTCGACC
AGTCGCCCATCGGCCGCACCCCGCGGTCGAACCCGGCGACGTACACCGGAGTCTTCGACCACGTCCGCAAGCTCTTCGCG
GAGACCACGGAGGCGAAGGTGCGGGGTTACCTCCCCGGGCGCTTCTCCTTCAACGTCAAGGGCGGTCGCTGCGAGAACTG
CTCCGGTGACGGCACCATCAAGATCGAGATGAACTTCCTGCCGGACGTGTACGTCCCGTGCGAGGTCTGCCACGGCGCGC
GCTACAACCGCGAGACGCTGGACGTCCACTACAAGGGCAAGTCCATCGCCGAGGTCCTCGACATGCCGATCGAGGAGGCG
CTCGGCTTCTTCGAGGCCGTGCCCGCCATCGCCCGCCACCTGAAGACGCTCACGGACGTCGGCCTGGGGTACGTGCGCCT
CGGCCAGTCCGCGCCCACGCTCTCCGGAGGCGAGGCCCAGCGCGTGAAGCTGGCCTCCGAGCTCCAGAAGCGCTCCACGG
GCCGGACCGTCTACGTCCTGGACGAGCCGACCACCGGTCTGCACTTCGAGGACATCAGCAAGCTGATCACGGTCCTCTCC
GGTCTGGTCGACAAGGGCAACACGGTCATCGTCATCGAGCACAACCTCGACGTGATCAAGACCGCGGACTGGGTCGTCGA
CATGGGCCCCGAGGGGGGCAGCGGCGGCGGTCTGGTCGTCGCCGAGGGCACGCCGGAGGAGGTCGCAGGGGTGTCGACGA
GCCACACCGGCAAGTTCCTTCGGGAGATCATCTCGGCCGACCGGATCAGCGACGCGCTGCCCTCGCAGGGGCGCAAGCCG
GCCAAGAAGGCGACGGCGAAGAAGGCCACCGCCAAGCGGGCGGTGGCGGCGAGCGCCACCGCCACGAAGAAGACGGCCAC
GGTCAGGACCGGCACGGCCGCCGCCGACAAGCCGACGGCCACCGCCAAGAAGGCCGCCGCCACCACGAAGAAGACGGCCG
CCGCCACCAAGAAGGCCGCCGCGAAGAAGACGGCGACGCGGGCCCGCAAGGCCTGA

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(131-238)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-403)

ABC transporter (ABC_tran)

(628-864)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

57.143

91.659

0.524
  uvrA Streptococcus pneumoniae TIGR4

57.143

91.659

0.524
  uvrA Streptococcus pneumoniae D39

57.143

91.659

0.524