Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   KIK01_RS02195 Genome accession   NZ_CP075489
Coordinates   447546..449507 (+) Length   653 a.a.
NCBI ID   WP_035144579.1    Uniprot ID   -
Organism   Latilactobacillus sakei subsp. sakei strain ob4.1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 442546..454507
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KIK01_RS02185 (KIK01_02185) - 444091..444897 (+) 807 WP_016264637.1 TIGR00282 family metallophosphoesterase -
  KIK01_RS02190 (KIK01_02190) hexA 444919..447522 (+) 2604 WP_076645117.1 DNA mismatch repair protein MutS Machinery gene
  KIK01_RS02195 (KIK01_02195) hexB 447546..449507 (+) 1962 WP_035144579.1 DNA mismatch repair endonuclease MutL Machinery gene
  KIK01_RS02200 (KIK01_02200) - 449507..450052 (+) 546 WP_016264640.1 Maf family protein -
  KIK01_RS02205 (KIK01_02205) - 450065..450628 (+) 564 WP_016264641.1 TIGR00730 family Rossman fold protein -
  KIK01_RS02210 (KIK01_02210) ruvA 450879..451490 (+) 612 WP_016264642.1 Holliday junction branch migration protein RuvA Machinery gene
  KIK01_RS02215 (KIK01_02215) ruvB 451503..452510 (+) 1008 WP_016264643.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  KIK01_RS02220 (KIK01_02220) queA 452525..453556 (+) 1032 WP_011374077.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  KIK01_RS02225 (KIK01_02225) - 453583..454104 (+) 522 WP_016264644.1 GNAT family protein -

Sequence

Protein


Download         Length: 653 a.a.        Molecular weight: 72748.15 Da        Isoelectric Point: 5.4265

>NTDB_id=498677 KIK01_RS02195 WP_035144579.1 447546..449507(+) (hexB) [Latilactobacillus sakei subsp. sakei strain ob4.1]
MGKIHELSEILSNQIAAGEVIERPASVVKELVENAIDANSTQVDIVVEQAGLQMIQVIDNGDGIEPEDVPVAFKRHATSK
IATRQDLFKIQSLGFRGEALASIASVSDLTIETATADSLGTFAHFKGGLLEEQKTNPIRPGTAITVRDLFFNTPARLKYV
KTFQTELANIVDIVNRLAMSHPQIAFTLTNDDHLLLKTAGNNDLKQTIAGIYGVTMAKKLLAVSASDLDFKLTGYVSLPE
LTRATRNYLSILINGRFIKNYQLNKAIIKGYGSKLMVGRYPIAVLAIEMDPLLIDVNVHPTKQEVRLSKETALMTLIEGA
IKERLATENLIPDAMQNLKRTKTVDVDQLQMNLNQITQERRHPSGTVRPVSPMPATTVKPVTPEIAETETPLAAPTAKAP
AMTPERPLFEQPQALAEWDQKYATEAVGKPFGDQVVDETDENDETVVEPTVRFPELRYIGQLHSTFLLAEGEDGFYILDQ
HAAQERIKYEYYREKIGEVSTSVQNLLVPLVLEYPNSDALKIQEKTELLASVGIQLENFGQNSFVVHSHPTWIEQGQEEM
TIRGMIDDVLKDGRISIAQFREKTAIMMSCKQSIKAHHHLDDAQAKALLADLAKTENPFNCPHGRPVLIHYTQKDLEKMF
KRIQEPHHSWEGE

Nucleotide


Download         Length: 1962 bp        

>NTDB_id=498677 KIK01_RS02195 WP_035144579.1 447546..449507(+) (hexB) [Latilactobacillus sakei subsp. sakei strain ob4.1]
ATGGGGAAAATTCATGAACTGTCGGAAATTCTAAGTAATCAAATTGCGGCGGGGGAAGTGATTGAACGCCCTGCCTCAGT
GGTCAAGGAATTGGTTGAAAACGCGATTGATGCCAATAGTACGCAAGTCGATATTGTTGTTGAACAGGCCGGTTTACAGA
TGATTCAAGTGATCGATAATGGTGACGGGATTGAACCAGAAGATGTGCCAGTCGCCTTTAAGCGGCATGCCACCAGTAAG
ATTGCGACTCGGCAAGATTTGTTCAAGATTCAATCGCTAGGGTTTCGGGGTGAAGCGTTAGCTAGTATCGCGTCCGTTTC
CGATTTAACGATTGAAACGGCAACTGCGGACTCTCTAGGAACCTTTGCTCATTTTAAGGGTGGTCTGTTAGAGGAACAAA
AAACAAATCCGATTCGACCGGGGACGGCGATTACGGTGCGGGATTTATTCTTTAATACACCGGCACGATTGAAATACGTG
AAGACTTTTCAAACCGAATTGGCGAATATCGTCGATATCGTCAATCGGCTAGCAATGAGCCATCCACAGATTGCTTTCAC
GCTAACCAATGATGACCATCTACTTTTAAAAACGGCCGGCAACAATGATTTAAAACAAACGATTGCTGGTATTTATGGCG
TCACCATGGCCAAGAAACTCTTAGCCGTGAGTGCTTCGGATTTAGATTTTAAACTAACGGGCTACGTGTCATTGCCGGAA
TTAACGCGGGCAACGCGCAATTATTTGTCGATTTTAATTAATGGTCGGTTTATTAAAAATTACCAATTGAATAAGGCCAT
TATCAAGGGCTACGGTTCTAAATTGATGGTCGGACGCTATCCAATCGCCGTCTTAGCGATTGAGATGGATCCGCTATTGA
TTGATGTCAACGTGCATCCAACAAAACAGGAAGTCCGCTTAAGCAAAGAAACTGCCTTGATGACCTTGATTGAAGGGGCA
ATCAAAGAAAGACTGGCAACCGAGAATTTAATTCCAGATGCCATGCAGAATTTGAAACGGACCAAGACGGTAGATGTTGA
TCAGCTCCAGATGAATTTAAACCAAATTACACAAGAACGACGGCACCCAAGCGGTACGGTGCGACCAGTCAGTCCAATGC
CAGCCACAACGGTCAAACCGGTGACACCAGAAATTGCGGAAACCGAAACGCCGTTAGCCGCACCAACTGCTAAAGCGCCG
GCGATGACACCGGAGCGGCCCTTATTTGAGCAACCCCAGGCATTGGCCGAGTGGGATCAGAAGTATGCGACCGAAGCAGT
TGGGAAGCCATTTGGTGACCAAGTGGTAGACGAAACGGACGAAAACGATGAAACCGTAGTCGAACCCACTGTTCGTTTTC
CGGAGTTACGCTACATTGGGCAACTGCACAGTACTTTCTTATTAGCGGAAGGCGAAGATGGCTTTTATATCTTGGATCAA
CACGCTGCGCAAGAACGGATTAAGTACGAGTATTACCGAGAAAAAATTGGGGAAGTCAGCACCTCTGTGCAAAACTTGTT
AGTACCGCTTGTTTTGGAATATCCGAATAGTGATGCGCTAAAGATTCAGGAAAAAACTGAACTCTTGGCGTCAGTCGGAA
TTCAATTAGAAAATTTCGGGCAGAATAGTTTTGTGGTCCACAGTCACCCAACTTGGATTGAACAGGGACAAGAGGAAATG
ACGATTCGTGGGATGATTGACGATGTTTTAAAAGACGGCCGCATTAGTATTGCTCAATTCCGTGAGAAGACGGCGATTAT
GATGAGCTGTAAGCAATCAATCAAGGCACACCATCATTTAGATGATGCCCAGGCCAAAGCGCTTTTAGCCGATCTAGCGA
AGACCGAGAATCCGTTTAATTGTCCCCACGGACGCCCGGTTTTGATTCACTACACGCAAAAAGATTTGGAAAAGATGTTT
AAACGGATTCAAGAACCACATCATAGTTGGGAGGGCGAATAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(456-600)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(208-325)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-136)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

49.848

100

0.504