Detailed information NTG0049848

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SSUA7_RS07605
• Genome accession: NC_017622
• Coordinates: 1536870..1537919 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis A7
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1531870..1542919

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUA7_RS07585 (SSUA7_1506)	nadE	1532154..1532978 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
SSUA7_RS07590 (SSUA7_1507)	-	1534396..1534923 (-)	528	WP_012027591.1	VanZ family protein	-
SSUA7_RS07595 (SSUA7_1508)	rlmN	1534920..1536032 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SSUA7_RS07600 (SSUA7_1509)	-	1536041..1536682 (-)	642	WP_012027595.1	YutD family protein	-
SSUA7_RS07605 (SSUA7_1510)	sepM	1536870..1537919 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
SSUA7_RS07610 (SSUA7_1511)	coaD	1537906..1538394 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
SSUA7_RS07615 (SSUA7_1512)	rsmD	1538384..1538923 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SSUA7_RS07620 (SSUA7_1513)	-	1539231..1539953 (-)	723	WP_012027598.1	lipoprotein	-
SSUA7_RS07625 (SSUA7_1514)	-	1540010..1540396 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
SSUA7_RS07630 (SSUA7_1515)	-	1540396..1540614 (-)	219	WP_004194736.1	YqgQ family protein	-
SSUA7_RS07635 (SSUA7_1516)	-	1540922..1541524 (-)	603	WP_012027601.1	response regulator transcription factor	-
SSUA7_RS07640 (SSUA7_1517)	-	1541521..1542615 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=49848 SSUA7_RS07605 WP_012775295.1 1536870..1537919(-) (sepM) [Streptococcus suis A7]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=49848 SSUA7_RS07605 WP_012775295.1 1536870..1537919(-) (sepM) [Streptococcus suis A7]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTATCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605