Detailed information NTG0049805

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SSUD12_RS09600
• Genome accession: NC_017621
• Coordinates: 1939921..1942374 (-)
• Length: 817 a.a.
• NCBI ID: WP_014638699.1
• Uniprot ID: -
• Organism: Streptococcus suis D12
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1934921..1947374

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUD12_RS09585 (SSUD12_1939)	hslO	1937353..1938219 (+)	867	WP_014638696.1	Hsp33 family molecular chaperone HslO	-
SSUD12_RS09590 (SSUD12_1940)	dusB	1938212..1939216 (+)	1005	WP_014638697.1	tRNA dihydrouridine synthase DusB	-
SSUD12_RS09595 (SSUD12_1941)	-	1939311..1939802 (-)	492	WP_014638698.1	adenylyltransferase/cytidyltransferase family protein	-
SSUD12_RS09600 (SSUD12_1942)	clpC	1939921..1942374 (-)	2454	WP_014638699.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SSUD12_RS09605 (SSUD12_1943)	-	1942378..1942836 (-)	459	WP_002937810.1	CtsR family transcriptional regulator	-
SSUD12_RS09610 (SSUD12_1944)	-	1943107..1943445 (+)	339	WP_014638700.1	thioredoxin domain-containing protein	-
SSUD12_RS09615 (SSUD12_1945)	-	1943445..1944146 (+)	702	WP_014638701.1	hypothetical protein	-
SSUD12_RS09620 (SSUD12_1946)	tsf	1944407..1945447 (-)	1041	WP_014638702.1	translation elongation factor Ts	-
SSUD12_RS09625 (SSUD12_1947)	rpsB	1945603..1946379 (-)	777	WP_012775356.1	30S ribosomal protein S2	-

Sequence

Protein

• Length: 817 a.a.
• Molecular weight: 90505.03 Da
• Isoelectric Point: 6.2915

>NTDB_id=49805 SSUD12_RS09600 WP_014638699.1 1939921..1942374(-) (clpC) [Streptococcus suis D12]
MKISTGLQRVFEDAQLVAQRYACDYLETWHVLLSFVINHDTVAGAVLAEYPISISDYEHATFVVTDKVYREELDSFRILP
SSKRLDETASFAKKIAEVVKAKELGTEHLFMAMLLDKRSTASQILDKVGFYFEDSDDKFRFLDLRKNLEARAGFTKEDLK
AIRSVMKGGKAKPTNMGQMMGMPPAPQSGGLEDYTRDLTALAREGKIEPVIGRDAEIARMIQILSRKTKNNPVLVGDAGV
GKTALALGLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQTEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGQAAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQAEETGLTSIDKALMDKKYKTVSKLLIKTKEDAEASQNYDLEV
TEEDVLETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTETHMQDVVKVMIKPLLAVTAEKGITLKLQPSALKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGDLTTGST
LKVGVKGEELKFDVVKG

Nucleotide

• Length: 2454 bp

>NTDB_id=49805 SSUD12_RS09600 WP_014638699.1 1939921..1942374(-) (clpC) [Streptococcus suis D12]
ATGAAAATTTCAACTGGTTTACAGCGGGTTTTTGAAGATGCCCAGTTAGTGGCCCAACGTTATGCCTGTGATTACTTGGA
AACCTGGCATGTTCTCTTGTCTTTCGTTATCAACCATGATACAGTCGCTGGCGCTGTTTTGGCAGAATATCCTATTTCAA
TTTCTGACTATGAACATGCAACTTTTGTTGTGACCGACAAGGTCTATCGTGAAGAGTTGGATAGTTTTCGTATTTTACCA
TCTTCTAAACGTTTGGATGAAACAGCTAGTTTTGCCAAGAAAATTGCAGAAGTCGTCAAGGCTAAGGAGCTGGGAACGGA
ACATTTGTTTATGGCTATGTTGTTGGACAAGCGGTCAACAGCTAGTCAGATTTTGGACAAGGTAGGTTTTTATTTTGAAG
ACTCAGATGATAAGTTTCGTTTCTTGGATTTGCGTAAAAACTTGGAGGCACGTGCGGGATTTACCAAAGAGGACCTTAAA
GCTATCCGCAGTGTGATGAAGGGTGGCAAAGCCAAACCTACCAATATGGGACAGATGATGGGAATGCCCCCAGCACCTCA
AAGTGGTGGATTAGAAGACTACACTCGTGATTTGACAGCTTTGGCGCGTGAAGGGAAGATTGAACCTGTCATCGGTCGAG
ACGCTGAGATTGCACGGATGATCCAAATTCTATCACGTAAAACCAAGAACAACCCAGTTCTAGTTGGTGATGCTGGTGTC
GGAAAAACTGCGCTTGCTTTGGGTCTTGCTCAACGTGTTGCTGCAGGTGATGTCCCTGTCAGCTTAGCTAAGATGCGGGT
TTTGGAACTTGACTTGATGAACGTTATCGCTGGAACTCGTTTCCGTGGTGATTTCGAAGAGCGGATGAATAATATCATCA
ACGACATCGAGGAAGATGGTCAGGTCATCCTTTTCATCGATGAGTTGCATACCATTATGGGTTCTGGCTCGGGGATTGAT
TCGACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTTGCTCGTGGCACCCTCCGTACGGTCGGAGCGACGACTCAGAC
AGAGTACCAAAAGCATATTGAGAAAGACGCAGCCCTGGTTCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTGG
AAGATAGCATTGCCATTTTGACTGGTTTAAAAGGTACTTTTGAAAAATACCACAGGGTCCGTATTGGACAAGCAGCTGTA
GAGACTGCTGTGACCTACGCTAAGCGGTATTTGACCAGTAAAAACCTGCCAGATTCTGCCATTGATCTGCTGGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGGCAGGCTGAGGAAACAGGACTGACGAGCATAGACAAGGCCTTGATGGATA
AAAAATATAAGACTGTCAGCAAGCTTTTGATTAAAACGAAAGAAGATGCCGAGGCTAGTCAAAACTATGACCTTGAAGTA
ACAGAAGAAGATGTTTTAGAAACACTTAGCCGCTTGTCAGGTATCCCAGTAGCCAAGCTTAGCCAATCAGATACTAAGAA
GTATCTGAATCTGGAAGCAGAATTGCATAAGCGTGTGATTGGGCAGGAAGAAGCTATTTCTGCTGTTAGCAGAGCTATTC
GTCGTAATCAGTCAGGGATTCGTACAGGTCGCAGACCGATTGGTTCCTTTATGTTCTTGGGACCGACTGGTGTCGGTAAG
ACAGAGCTTGCTAAAGCCTTGGCGGAGGTTCTCTTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCTGAGTATAT
GGAGAAATTTGCGGCCAGCCGTCTCAATGGAGCGCCTCCGGGCTACGTGGGCTATGAAGAAGGTGGCGAATTGACAGAAA
AAGTTCGTAATAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTCAATGTTCTCTTG
CAGGTCTTGGATGATGGTGTCTTGACGGACAGTAAGGGACGTAAGGTTGATTTTTCAAATACTATTATTATCATGACGTC
AAACCTTGGAGCAACAGCCCTTCGTGATGATAAGACAGTTGGTTTTGGTGCCCTTGATTTATCTAAGGACCACAAGGAAG
TGGAGAAACGCATTTTTGAGGAATTGAAAAAAGCCTATCGTCCAGAATTTATCAACCGCATTGACGAGAAAGTTGTCTTC
CATAGCCTAACGGAAACTCATATGCAGGATGTTGTCAAGGTCATGATTAAACCTTTGTTGGCTGTAACAGCTGAGAAAGG
AATTACTCTTAAACTGCAACCGTCAGCCCTTAAGTTATTGGCTAAACAAGGTTATGACCCAGAAATGGGGGCTCGTCCTC
TTCGTAGACTCTTGCAGACCAAGTTGGAAGATCCGTTGGCAGAAATGTTACTCCGTGGTGACTTGACTACTGGTTCGACC
TTGAAGGTTGGGGTCAAGGGTGAAGAGCTCAAGTTTGATGTGGTAAAGGGATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (372-457)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-130)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-56)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	71.902	99.755	0.717
clpC	Streptococcus pneumoniae D39	71.902	99.755	0.717
clpC	Streptococcus pneumoniae TIGR4	71.902	99.755	0.717
clpC	Streptococcus mutans UA159	66.708	99.633	0.665
clpC	Streptococcus thermophilus LMD-9	63.962	100	0.656
clpC	Streptococcus thermophilus LMG 18311	64.38	100	0.655
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.222	100	0.503
clpC	Bacillus subtilis subsp. subtilis str. 168	43.353	100	0.443