Detailed information NTG0049705

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SSU12_RS09460
• Genome accession: NC_017619
• Coordinates: 1892755..1895208 (-)
• Length: 817 a.a.
• NCBI ID: WP_012027858.1
• Uniprot ID: A0A2K1SY42
• Organism: Streptococcus suis SS12
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1887755..1900208

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSU12_RS09435 (SSU12_1907)	hslO	1887998..1888864 (+)	867	WP_012027852.1	Hsp33 family molecular chaperone HslO	-
SSU12_RS09440 (SSU12_1908)	dusB	1888857..1889861 (+)	1005	WP_012775355.1	tRNA dihydrouridine synthase DusB	-
SSU12_RS09445 (SSU12_1909)	-	1890007..1890780 (-)	774	WP_012027854.1	NUDIX domain-containing protein	-
SSU12_RS09450 (SSU12_1910)	pnuC	1890773..1891594 (-)	822	WP_012027855.1	nicotinamide riboside transporter PnuC	-
SSU12_RS09455 (SSU12_1911)	-	1891604..1892641 (-)	1038	WP_012028524.1	AAA family ATPase	-
SSU12_RS09460 (SSU12_1912)	clpC	1892755..1895208 (-)	2454	WP_012027858.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SSU12_RS09465 (SSU12_1913)	-	1895214..1895672 (-)	459	WP_012027859.1	CtsR family transcriptional regulator	-
SSU12_RS09470 (SSU12_1914)	-	1895822..1896160 (+)	339	WP_012027860.1	thioredoxin domain-containing protein	-
SSU12_RS09475 (SSU12_1915)	-	1896160..1896861 (+)	702	WP_012027861.1	hypothetical protein	-
SSU12_RS09480 (SSU12_1916)	tsf	1897124..1898164 (-)	1041	WP_012027862.1	translation elongation factor Ts	-
SSU12_RS09485 (SSU12_1917)	rpsB	1898320..1899096 (-)	777	WP_012775356.1	30S ribosomal protein S2	-
SSU12_RS09490 (SSU12_1918)	-	1899443..1899955 (-)	513	WP_012775452.1	adenylate kinase	-

Sequence

Protein

• Length: 817 a.a.
• Molecular weight: 90132.53 Da
• Isoelectric Point: 6.3138

>NTDB_id=49705 SSU12_RS09460 WP_012027858.1 1892755..1895208(-) (clpC) [Streptococcus suis SS12]
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG

Nucleotide

• Length: 2454 bp

>NTDB_id=49705 SSU12_RS09460 WP_012027858.1 1892755..1895208(-) (clpC) [Streptococcus suis SS12]
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGGCTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-54)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (104-130)

• ATPase family associated with various cellular activities (AAA) (AAA) (232-364)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

• AAA lid domain (AAA_lid_9) (371-451)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-802)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae TIGR4	71.464	99.51	0.711
clpC	Streptococcus pneumoniae Rx1	71.464	99.51	0.711
clpC	Streptococcus pneumoniae D39	71.464	99.51	0.711
clpC	Streptococcus mutans UA159	66.173	99.143	0.656
clpC	Streptococcus thermophilus LMG 18311	64.828	99.878	0.647
clpC	Streptococcus thermophilus LMD-9	64.706	99.878	0.646
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.086	100	0.492
clpC	Bacillus subtilis subsp. subtilis str. 168	44.403	99.51	0.442