Detailed information
Bioinformatically predicted
Overview
| Name | clpC | Type | Regulator |
| Locus tag | SSU12_RS09460 | Genome accession | NC_017619 |
| Coordinates | 1892755..1895208 (-) | Length | 817 a.a. |
| NCBI ID | WP_012027858.1 | Uniprot ID | A0A2K1SY42 |
| Organism | Streptococcus suis SS12 | ||
| Function | degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 1888857..1932575 | 1892755..1895208 | within | 0 |
Gene organization within MGE regions
Location: 1888857..1932575
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SSU12_RS09440 (SSU12_1908) | dusB | 1888857..1889861 (+) | 1005 | WP_012775355.1 | tRNA dihydrouridine synthase DusB | - |
| SSU12_RS09445 (SSU12_1909) | - | 1890007..1890780 (-) | 774 | WP_012027854.1 | NUDIX domain-containing protein | - |
| SSU12_RS09450 (SSU12_1910) | pnuC | 1890773..1891594 (-) | 822 | WP_012027855.1 | nicotinamide riboside transporter PnuC | - |
| SSU12_RS09455 (SSU12_1911) | - | 1891604..1892641 (-) | 1038 | WP_012028524.1 | AAA family ATPase | - |
| SSU12_RS09460 (SSU12_1912) | clpC | 1892755..1895208 (-) | 2454 | WP_012027858.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| SSU12_RS09465 (SSU12_1913) | - | 1895214..1895672 (-) | 459 | WP_012027859.1 | CtsR family transcriptional regulator | - |
| SSU12_RS09470 (SSU12_1914) | - | 1895822..1896160 (+) | 339 | WP_012027860.1 | thioredoxin domain-containing protein | - |
| SSU12_RS09475 (SSU12_1915) | - | 1896160..1896861 (+) | 702 | WP_012027861.1 | hypothetical protein | - |
| SSU12_RS09480 (SSU12_1916) | tsf | 1897124..1898164 (-) | 1041 | WP_012027862.1 | translation elongation factor Ts | - |
| SSU12_RS09485 (SSU12_1917) | rpsB | 1898320..1899096 (-) | 777 | WP_012775356.1 | 30S ribosomal protein S2 | - |
| SSU12_RS09490 (SSU12_1918) | - | 1899443..1899955 (-) | 513 | WP_012775452.1 | adenylate kinase | - |
| SSU12_RS09500 (SSU12_1919) | - | 1900609..1905687 (-) | 5079 | WP_012775357.1 | S8 family serine peptidase | - |
| SSU12_RS09505 (SSU12_1920) | nusG | 1905831..1906370 (-) | 540 | WP_002940254.1 | transcription termination/antitermination protein NusG | - |
| SSU12_RS09510 (SSU12_1921) | secE | 1906480..1906656 (-) | 177 | WP_002940255.1 | preprotein translocase subunit SecE | - |
| SSU12_RS09515 (SSU12_1922) | rpmG | 1906666..1906818 (-) | 153 | WP_002940258.1 | 50S ribosomal protein L33 | - |
| SSU12_RS09520 (SSU12_1923) | pbp2a | 1906852..1909065 (-) | 2214 | WP_012027868.1 | penicillin-binding protein PBP2A | - |
| SSU12_RS09525 (SSU12_1924) | - | 1909218..1910186 (+) | 969 | WP_012027869.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| SSU12_RS09530 (SSU12_1925) | - | 1910188..1911036 (+) | 849 | WP_014636718.1 | RluA family pseudouridine synthase | - |
| SSU12_RS09535 (SSU12_1926) | purR | 1911063..1911875 (-) | 813 | WP_002938438.1 | pur operon repressor | - |
| SSU12_RS09540 (SSU12_1927) | - | 1911977..1912843 (-) | 867 | WP_012027872.1 | aminoglycoside phosphotransferase family protein | - |
| SSU12_RS09545 (SSU12_1928) | - | 1912843..1913784 (-) | 942 | WP_012775359.1 | 3'-5' exoribonuclease YhaM family protein | - |
| SSU12_RS09550 (SSU12_1929) | - | 1913774..1915012 (-) | 1239 | WP_012027874.1 | DNA recombination protein RmuC | - |
| SSU12_RS09555 (SSU12_1930) | - | 1915013..1915645 (-) | 633 | WP_012027875.1 | thiamine diphosphokinase | - |
| SSU12_RS09560 (SSU12_1931) | rpe | 1915638..1916297 (-) | 660 | WP_012027876.1 | ribulose-phosphate 3-epimerase | - |
| SSU12_RS09565 (SSU12_1932) | rsgA | 1916312..1917187 (-) | 876 | WP_012027877.1 | ribosome small subunit-dependent GTPase A | - |
| SSU12_RS09580 (SSU12_1935) | - | 1918593..1920170 (-) | 1578 | WP_012027878.1 | ABC transporter ATP-binding protein | - |
| SSU12_RS09585 (SSU12_1936) | - | 1920167..1921408 (-) | 1242 | WP_014636518.1 | radical SAM protein | - |
| SSU12_RS09590 (SSU12_1938) | - | 1921777..1922640 (-) | 864 | WP_012027880.1 | helix-turn-helix domain-containing protein | - |
| SSU12_RS09600 (SSU12_1940) | - | 1923130..1925574 (-) | 2445 | WP_012027881.1 | LTA synthase family protein | - |
| SSU12_RS09605 (SSU12_1941) | - | 1925587..1927317 (-) | 1731 | WP_012775361.1 | membrane protein | - |
| SSU12_RS09610 (SSU12_1942) | rsmA | 1927682..1928554 (-) | 873 | WP_012775362.1 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA | - |
| SSU12_RS09615 (SSU12_1943) | - | 1928574..1929104 (-) | 531 | WP_009910909.1 | DUF1697 domain-containing protein | - |
| SSU12_RS09620 (SSU12_1944) | - | 1929118..1929375 (-) | 258 | WP_012775363.1 | Txe/YoeB family addiction module toxin | - |
| SSU12_RS09625 (SSU12_1945) | - | 1929377..1929637 (-) | 261 | WP_002939010.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| SSU12_RS09630 (SSU12_1946) | - | 1929713..1930168 (-) | 456 | WP_012028534.1 | 8-oxo-dGTP diphosphatase | - |
| SSU12_RS09635 (SSU12_1947) | - | 1930175..1930504 (-) | 330 | WP_012775364.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| SSU12_RS09640 (SSU12_1948) | - | 1930494..1930781 (-) | 288 | WP_012028535.1 | hypothetical protein | - |
| SSU12_RS09645 (SSU12_1949) | - | 1930879..1931247 (-) | 369 | WP_012775453.1 | hypothetical protein | - |
| SSU12_RS09650 (SSU12_1950) | rnmV | 1931240..1931809 (-) | 570 | WP_012775366.1 | ribonuclease M5 | - |
| SSU12_RS09655 (SSU12_1951) | - | 1931793..1932575 (-) | 783 | WP_012028536.1 | TatD family hydrolase | - |
Sequence
Protein
Download Length: 817 a.a. Molecular weight: 90132.53 Da Isoelectric Point: 6.3138
>NTDB_id=49705 SSU12_RS09460 WP_012027858.1 1892755..1895208(-) (clpC) [Streptococcus suis SS12]
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
Nucleotide
Download Length: 2454 bp
>NTDB_id=49705 SSU12_RS09460 WP_012027858.1 1892755..1895208(-) (clpC) [Streptococcus suis SS12]
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGGCTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGGCTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpC | Streptococcus pneumoniae TIGR4 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus pneumoniae Rx1 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus pneumoniae D39 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus mutans UA159 |
66.173 |
99.143 |
0.656 |
| clpC | Streptococcus thermophilus LMG 18311 |
64.828 |
99.878 |
0.647 |
| clpC | Streptococcus thermophilus LMD-9 |
64.706 |
99.878 |
0.646 |
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
48.086 |
100 |
0.492 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
44.403 |
99.51 |
0.442 |