Detailed information NTG0496933

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: IRE31_RS09270
• Genome accession: NZ_CP063829
• Coordinates: 1806491..1807528 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727280.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 19A-ST320_99-176
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1801491..1812528

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IRE31_RS09245 (IRE31_09190)	-	1802230..1803561 (-)	1332	WP_000390039.1	hemolysin family protein	-
IRE31_RS09250 (IRE31_09195)	endA	1803852..1804676 (-)	825	WP_001036785.1	DNA-entry nuclease EndA	Machinery gene
IRE31_RS09255 (IRE31_09200)	-	1804715..1804903 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
IRE31_RS09260 (IRE31_09205)	murA	1804896..1806179 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
IRE31_RS09265 (IRE31_09210)	-	1806203..1806433 (-)	231	WP_000615437.1	DUF1146 family protein	-
IRE31_RS09270 (IRE31_09215)	sepM	1806491..1807528 (-)	1038	WP_000727280.1	SepM family pheromone-processing serine protease	Regulator
IRE31_RS09275 (IRE31_09220)	coaD	1807512..1808000 (-)	489	WP_001280766.1	pantetheine-phosphate adenylyltransferase	-
IRE31_RS09280 (IRE31_09225)	rsmD	1807990..1808529 (-)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
IRE31_RS09285 (IRE31_09230)	asnA	1808594..1809586 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
IRE31_RS09290 (IRE31_09235)	-	1809698..1810381 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
IRE31_RS09295 (IRE31_09240)	-	1810437..1811177 (-)	741	WP_000152701.1	RNA methyltransferase	-
IRE31_RS09300 (IRE31_09245)	-	1811211..1811489 (+)	279	WP_001174613.1	acylphosphatase	-
IRE31_RS09305 (IRE31_09250)	yidC	1811567..1812493 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37567.60 Da
• Isoelectric Point: 5.0724

>NTDB_id=496933 IRE31_RS09270 WP_000727280.1 1806491..1807528(-) (sepM) [Streptococcus pneumoniae strain 19A-ST320_99-176]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=496933 IRE31_RS09270 WP_000727280.1 1806491..1807528(-) (sepM) [Streptococcus pneumoniae strain 19A-ST320_99-176]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591