Detailed information NTG0496922

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: IRE31_RS08605
• Genome accession: NZ_CP063829
• Coordinates: 1694928..1695995 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159553.1
• Uniprot ID: A0A0T8CF10
• Organism: Streptococcus pneumoniae strain 19A-ST320_99-176
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1689928..1700995

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IRE31_RS08580 (IRE31_08545)	treR	1690015..1690725 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
IRE31_RS08585 (IRE31_08550)	-	1690882..1692025 (+)	1144	Protein_1702	transposase	-
IRE31_RS08590 (IRE31_08555)	-	1692192..1693538 (+)	1347	WP_001814919.1	IS1380-like element ISSpn5 family transposase	-
IRE31_RS08595 (IRE31_08560)	-	1693731..1693916 (+)	186	Protein_1704	transposase	-
IRE31_RS08600 (IRE31_08565)	amiF	1693991..1694917 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
IRE31_RS08605 (IRE31_08570)	amiE	1694928..1695995 (-)	1068	WP_000159553.1	ABC transporter ATP-binding protein	Regulator
IRE31_RS08610 (IRE31_08575)	amiD	1696004..1696930 (-)	927	WP_000103702.1	oligopeptide ABC transporter permease OppC	Regulator
IRE31_RS08615 (IRE31_08580)	amiC	1696930..1698426 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
IRE31_RS08620 (IRE31_08585)	amiA3	1698493..1700472 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39437.04 Da
• Isoelectric Point: 4.8002

>NTDB_id=496922 IRE31_RS08605 WP_000159553.1 1694928..1695995(-) (amiE) [Streptococcus pneumoniae strain 19A-ST320_99-176]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=496922 IRE31_RS08605 WP_000159553.1 1694928..1695995(-) (amiE) [Streptococcus pneumoniae strain 19A-ST320_99-176]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTTGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0T8CF10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.761	100	0.868
amiE	Streptococcus thermophilus LMD-9	86.761	100	0.868
oppD	Streptococcus mutans UA159	54.545	99.155	0.541