Detailed information NTG0049645

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SSUJS14_RS08155
• Genome accession: NC_017618
• Coordinates: 1635211..1636260 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis JS14
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1630211..1641260

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUJS14_RS08135 (SSUJS14_1644)	nadE	1630617..1631441 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
SSUJS14_RS08140 (SSUJS14_1645)	-	1632737..1633264 (-)	528	WP_012027591.1	VanZ family protein	-
SSUJS14_RS08145 (SSUJS14_1646)	rlmN	1633261..1634373 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SSUJS14_RS08150 (SSUJS14_1647)	-	1634382..1635023 (-)	642	WP_012027595.1	YutD-like domain-containing protein	-
SSUJS14_RS08155 (SSUJS14_1648)	sepM	1635211..1636260 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
SSUJS14_RS08160 (SSUJS14_1649)	coaD	1636247..1636735 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
SSUJS14_RS08165 (SSUJS14_1650)	rsmD	1636725..1637264 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SSUJS14_RS08170 (SSUJS14_1651)	-	1637572..1638294 (-)	723	WP_012027598.1	lipoprotein	-
SSUJS14_RS08175 (SSUJS14_1652)	-	1638351..1638737 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
SSUJS14_RS08180 (SSUJS14_1653)	-	1638737..1638955 (-)	219	WP_004194736.1	YqgQ family protein	-
SSUJS14_RS08185 (SSUJS14_1654)	-	1639263..1639865 (-)	603	WP_012027601.1	response regulator transcription factor	-
SSUJS14_RS08190 (SSUJS14_1655)	-	1639862..1640956 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=49645 SSUJS14_RS08155 WP_012775295.1 1635211..1636260(-) (sepM) [Streptococcus suis JS14]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=49645 SSUJS14_RS08155 WP_012775295.1 1635211..1636260(-) (sepM) [Streptococcus suis JS14]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605