Detailed information NTG0496444

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF732_RS09925
• Genome accession: NZ_CP063745
• Coordinates: 2068439..2069326 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain NAS_AN_212
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2063439..2074326

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF732_RS09895 (IF732_09845)	-	2064172..2064933 (+)	762	WP_000323448.1	alpha/beta hydrolase family protein	-
IF732_RS09900 (IF732_09850)	-	2065177..2065632 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF732_RS13355	-	2065754..2065855 (+)	102	WP_000731972.1	SE2200 family small protein	-
IF732_RS09910 (IF732_09860)	-	2065915..2067339 (-)	1425	WP_000953736.1	alkaline phosphatase	-
IF732_RS09915 (IF732_09865)	-	2067537..2067737 (+)	201	WP_000604731.1	hypothetical protein	-
IF732_RS09920 (IF732_09870)	braR	2067763..2068428 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF732_RS09925 (IF732_09875)	braS	2068439..2069326 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF732_RS09930 (IF732_09880)	-	2069434..2070189 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
IF732_RS09935 (IF732_09885)	-	2070186..2072186 (+)	2001	WP_000776741.1	ABC transporter permease	-
IF732_RS09940 (IF732_09890)	-	2072855..2072968 (+)	114	WP_014937089.1	hypothetical protein	-
IF732_RS09945 (IF732_09895)	-	2073350..2073610 (+)	261	WP_014937088.1	hypothetical protein	-
IF732_RS09950 (IF732_09900)	-	2073620..2074117 (+)	498	WP_001065267.1	glutathione peroxidase	-
IF732_RS09955 (IF732_09905)	-	2074225..2074317 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=496444 IF732_RS09925 WP_000143420.1 2068439..2069326(+) (braS) [Staphylococcus aureus strain NAS_AN_212]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=496444 IF732_RS09925 WP_000143420.1 2068439..2069326(+) (braS) [Staphylococcus aureus strain NAS_AN_212]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993