Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   IP362_RS04550 Genome accession   NZ_CP063530
Coordinates   856404..858260 (+) Length   618 a.a.
NCBI ID   WP_006802343.1    Uniprot ID   A0A2N3PK43
Organism   Helicobacter winghamensis strain DSM 111488     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 851404..863260
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IP362_RS04515 (IP362_04460) hemJ 851546..851977 (-) 432 WP_006802351.1 protoporphyrinogen oxidase HemJ -
  IP362_RS04520 (IP362_04465) - 852138..852776 (+) 639 WP_040498599.1 amino acid ABC transporter permease -
  IP362_RS04525 (IP362_04470) - 852781..853434 (+) 654 WP_006802349.1 amino acid ABC transporter permease -
  IP362_RS04530 (IP362_04475) - 853440..854180 (+) 741 WP_006802348.1 amino acid ABC transporter ATP-binding protein -
  IP362_RS04535 (IP362_04480) - 854189..854362 (-) 174 WP_156777715.1 hypothetical protein -
  IP362_RS04540 (IP362_04485) - 854373..855842 (-) 1470 WP_006802346.1 L-aspartate oxidase -
  IP362_RS04545 (IP362_04490) - 855948..856397 (+) 450 WP_040498499.1 hypothetical protein -
  IP362_RS04550 (IP362_04495) uvrC 856404..858260 (+) 1857 WP_006802343.1 excinuclease ABC subunit UvrC Machinery gene
  IP362_RS04555 (IP362_04500) - 858229..858714 (-) 486 WP_006802342.1 hypothetical protein -
  IP362_RS04560 (IP362_04505) cutA 858756..859082 (-) 327 WP_248613379.1 divalent cation tolerance protein CutA -
  IP362_RS04565 (IP362_04510) - 859091..859366 (-) 276 WP_006802340.1 hypothetical protein -
  IP362_RS04570 (IP362_04515) - 859368..860180 (-) 813 WP_006802339.1 hypothetical protein -
  IP362_RS04575 (IP362_04520) - 860189..860932 (-) 744 WP_006802338.1 DUF5644 domain-containing protein -
  IP362_RS04580 (IP362_04525) - 860976..861449 (-) 474 WP_006802337.1 hypothetical protein -
  IP362_RS04585 (IP362_04530) - 861451..863199 (-) 1749 WP_006802336.1 M3 family oligoendopeptidase -

Sequence

Protein


Download         Length: 618 a.a.        Molecular weight: 71119.45 Da        Isoelectric Point: 9.6292

>NTDB_id=496073 IP362_RS04550 WP_006802343.1 856404..858260(+) (uvrC) [Helicobacter winghamensis strain DSM 111488]
MESNFKPLSQNLLETLKKIPNSSGVYHYFDTQGKLLYVGKAKNLKHRIKSYFRFTPNLAPAPNLSPRITQMVSQIAHLRY
IVVENENDALILENSLIKQLKPKYNVLLRDDKTYPYLCVDLQEDFPRILLTRKIFKKQGLRYFGPFSSGARDLLDSIYEI
FPLAQKESCKNGKKACLFYQIHRCLAPCEGKISTKDYAKILQNALECVENPKKILAPLEQKMLQLSQNLRFEEALILRDR
IAKIKNLTPLSSVDFANLVDLDIFALVCEDKRAVLVKFFMRNGKIISSATQNLKSELGFDSLSIYKQALINHYSNTLPLV
PKQILIPFDLGESTQELEYFLQEKVGKKVQIHFPKSGDKKRLCELAIQNGKEILRLEQNDNEEIFNALKTLFCLQNTPYR
FEVFDTSHHKGTQCVGAMVVYDGLDFIKESYRHYLLEGKDEYTQMREMLTRRIQDFQKESPPDLWVLDGGAGQINLAKEL
LESAGVNLEVIGIAKEKIDSKTHRAKGGAKDILRDENLKEYRLSMSDKRLQFLQKLRDEAHRFAITFHQKQKQKTMQHSK
LLSIKGIGKAIQNKLLAYFGSFEAIEKADLDELEKVLSKTFAKSVFNALRSFQNNAQH

Nucleotide


Download         Length: 1857 bp        

>NTDB_id=496073 IP362_RS04550 WP_006802343.1 856404..858260(+) (uvrC) [Helicobacter winghamensis strain DSM 111488]
ATGGAATCCAATTTTAAGCCCCTATCACAAAACCTACTAGAAACTTTAAAAAAGATTCCAAATTCTAGCGGTGTGTATCA
TTATTTTGACACGCAAGGCAAGTTGCTTTATGTGGGCAAGGCAAAGAATCTAAAACATCGCATTAAAAGTTATTTTCGTT
TCACTCCAAACTTAGCTCCCGCACCAAATTTAAGCCCAAGAATTACGCAAATGGTTAGTCAAATCGCACATTTACGCTAT
ATTGTTGTGGAGAACGAAAATGACGCGCTAATCTTAGAAAACTCCCTAATTAAGCAACTTAAGCCAAAATACAATGTGTT
ATTGCGCGATGATAAAACTTATCCGTATTTATGCGTGGATTTACAAGAAGATTTTCCGCGCATTTTACTCACTAGAAAAA
TTTTTAAAAAGCAAGGATTGCGCTATTTTGGACCTTTTTCAAGCGGTGCTAGGGATCTTTTGGATTCCATCTATGAAATT
TTCCCACTTGCACAAAAAGAATCGTGCAAAAATGGCAAAAAAGCCTGTCTTTTTTATCAAATCCATCGCTGTTTAGCTCC
CTGTGAAGGTAAAATTTCTACCAAAGACTATGCAAAGATTCTCCAAAATGCCTTAGAGTGCGTAGAAAATCCTAAAAAAA
TCCTAGCACCATTGGAGCAAAAAATGCTTCAACTCTCACAAAATTTACGCTTTGAAGAAGCTCTAATCTTGCGCGATAGG
ATTGCAAAAATTAAAAACCTAACCCCTTTATCTTCTGTGGATTTTGCAAATTTAGTAGATTTAGATATTTTTGCACTTGT
CTGCGAAGATAAACGCGCTGTGCTTGTAAAATTCTTTATGCGTAATGGCAAAATTATCTCAAGTGCGACACAAAATCTTA
AAAGTGAATTAGGATTTGATAGTTTAAGCATTTATAAACAGGCACTAATTAACCACTACTCTAACACCCTTCCGCTAGTT
CCAAAACAAATTCTAATTCCCTTTGATTTAGGTGAAAGCACGCAAGAGTTGGAATACTTTTTGCAAGAAAAAGTTGGCAA
AAAAGTCCAAATCCACTTCCCAAAAAGTGGTGATAAAAAACGCCTATGCGAGCTTGCAATACAGAATGGAAAAGAGATTT
TACGCCTAGAACAAAATGATAATGAAGAAATTTTTAACGCCTTAAAAACGCTCTTTTGCCTACAAAATACGCCCTATCGC
TTTGAAGTTTTTGATACCTCTCACCACAAAGGCACACAATGCGTTGGAGCAATGGTTGTGTATGATGGCTTGGATTTTAT
CAAGGAATCTTATCGCCATTATTTACTAGAAGGCAAAGATGAATACACACAAATGCGTGAAATGCTAACACGGCGCATAC
AAGATTTTCAAAAAGAATCCCCGCCTGATTTATGGGTGCTTGATGGGGGGGCTGGACAGATTAATCTTGCAAAAGAGTTG
CTAGAGAGTGCGGGAGTTAATTTAGAAGTTATAGGGATTGCAAAAGAGAAGATTGATAGCAAGACTCACCGCGCAAAAGG
CGGTGCAAAAGACATTTTAAGAGATGAAAATTTAAAGGAATATCGCCTAAGTATGAGCGATAAACGCTTGCAATTTTTAC
AAAAATTGCGCGATGAAGCACATCGCTTTGCAATCACCTTTCACCAAAAGCAAAAGCAAAAAACAATGCAACACTCTAAA
CTTTTAAGCATTAAAGGCATAGGCAAAGCTATCCAAAACAAGCTCTTAGCCTATTTTGGAAGTTTTGAAGCCATTGAAAA
GGCAGACTTAGATGAGCTTGAAAAAGTGCTATCAAAAACCTTTGCTAAATCCGTTTTTAATGCGCTTAGAAGTTTCCAAA
ATAACGCACAGCACTGA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(212-246)

GIY-YIG catalytic domain (GIY-YIG)

(23-105)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(391-545)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2N3PK43

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

57.022

95.631

0.545