Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   IP363_RS03835 Genome accession   NZ_CP063529
Coordinates   746949..748805 (-) Length   618 a.a.
NCBI ID   WP_370523317.1    Uniprot ID   -
Organism   Helicobacter winghamensis strain DoED 18-7711     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 741949..753805
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IP363_RS03800 (IP363_03770) - 742010..743758 (+) 1749 WP_006802336.1 M3 family oligoendopeptidase -
  IP363_RS03805 (IP363_03775) - 743760..744233 (+) 474 WP_006802337.1 hypothetical protein -
  IP363_RS03810 (IP363_03780) - 744277..745020 (+) 744 WP_006802338.1 DUF5644 domain-containing protein -
  IP363_RS03815 (IP363_03785) - 745029..745841 (+) 813 WP_006802339.1 hypothetical protein -
  IP363_RS03820 (IP363_03790) - 745843..746118 (+) 276 WP_006802340.1 hypothetical protein -
  IP363_RS03825 (IP363_03795) cutA 746127..746453 (+) 327 WP_248613379.1 divalent cation tolerance protein CutA -
  IP363_RS03830 (IP363_03800) - 746495..746980 (+) 486 WP_006802342.1 hypothetical protein -
  IP363_RS03835 (IP363_03805) uvrC 746949..748805 (-) 1857 WP_370523317.1 excinuclease ABC subunit UvrC Machinery gene
  IP363_RS03840 (IP363_03810) - 748812..749261 (-) 450 WP_040498499.1 hypothetical protein -
  IP363_RS03845 (IP363_03815) - 749367..750836 (+) 1470 WP_006802346.1 L-aspartate oxidase -
  IP363_RS03850 (IP363_03820) - 750847..751020 (+) 174 WP_156777715.1 hypothetical protein -
  IP363_RS03855 (IP363_03825) - 751029..751769 (-) 741 WP_006802348.1 amino acid ABC transporter ATP-binding protein -
  IP363_RS03860 (IP363_03830) - 751775..752428 (-) 654 WP_006802349.1 amino acid ABC transporter permease -
  IP363_RS03865 (IP363_03835) - 752433..753071 (-) 639 WP_040498599.1 amino acid ABC transporter permease -
  IP363_RS03870 (IP363_03840) hemJ 753232..753663 (+) 432 WP_006802351.1 protoporphyrinogen oxidase HemJ -

Sequence

Protein


Download         Length: 618 a.a.        Molecular weight: 71118.51 Da        Isoelectric Point: 9.7197

>NTDB_id=496063 IP363_RS03835 WP_370523317.1 746949..748805(-) (uvrC) [Helicobacter winghamensis strain DoED 18-7711]
MESNFKPLSQNLLETLKKIPNSSGVYHYFDTQGKLLYVGKAKNLKHRIKSYFRFTPNLAPAPNLSPRITQMVSQIAHLRY
IVVENENDALILENSLIKQLKPKYNVLLRDDKTYPYLCVDLQEDFPRILLTRKIFKKQGLRYFGPFSSGARDLLDSIYEI
FPLAQKESCKNGKKACLFYQIHRCLAPCEGKISTKDYAKILQNALECVENPKKILAPLEQKMLQLSQNLRFEEALILRDR
IAKIKNLTPLSSVDFANLVDLDIFALVCEDKRAVLVKFFMRNGKIISSATQNLKSELGFDSLSIYKQALINHYSNTLPLV
PKQILIPFDLGESTQELEYFLQKKVGKKVQIHFPKSGDKKRLCELAIQNGKEILRLEQNDNEEIFNALKTLFCLQNTPYR
FEVFDTSHHKGTQCVGAMVVYDGLDFIKESYRHYLLEGKDEYTQMREMLTRRIQDFQKESPPDLWVLDGGAGQINLAKEL
LESAGVNLEVIGIAKEKIDSKTHRAKGGAKDILRDENLKEYRLSMSDKRLQFLQKLRDEAHRFAITFHQKQKQKTMQHSK
LLSIKGIGKAIQNKLLAYFGSFEAIEKADLDELEKVLSKTFAKSVFNALRSFQNNAQH

Nucleotide


Download         Length: 1857 bp        

>NTDB_id=496063 IP363_RS03835 WP_370523317.1 746949..748805(-) (uvrC) [Helicobacter winghamensis strain DoED 18-7711]
ATGGAATCCAATTTTAAGCCCCTATCACAAAACCTACTAGAAACTTTAAAAAAGATTCCAAATTCTAGCGGTGTGTATCA
TTATTTTGACACGCAAGGCAAGTTGCTTTATGTGGGCAAGGCAAAGAATCTAAAACATCGCATTAAAAGTTATTTTCGTT
TCACTCCAAACTTAGCTCCCGCACCAAATTTAAGCCCAAGAATTACGCAAATGGTTAGTCAAATCGCACATTTACGCTAT
ATTGTTGTGGAGAACGAAAATGACGCGCTAATCTTAGAAAACTCCCTAATTAAGCAACTTAAGCCAAAATACAATGTGTT
ATTGCGCGATGATAAAACTTATCCGTATTTATGCGTGGATTTACAAGAAGATTTTCCGCGCATTTTACTCACTAGAAAAA
TTTTTAAAAAGCAAGGATTGCGCTATTTTGGACCTTTTTCAAGCGGTGCTAGGGATCTTTTGGATTCCATCTATGAAATT
TTCCCACTTGCACAAAAAGAATCGTGCAAAAATGGCAAAAAAGCCTGTCTTTTTTATCAAATCCATCGCTGTTTAGCTCC
CTGTGAAGGTAAAATTTCTACCAAAGACTATGCAAAGATTCTCCAAAATGCCTTAGAGTGCGTAGAAAATCCTAAAAAAA
TCCTAGCACCATTGGAGCAAAAAATGCTTCAACTCTCACAAAATTTACGCTTTGAAGAAGCTCTAATCTTGCGCGATAGG
ATTGCAAAAATTAAAAACCTAACCCCTTTATCTTCTGTGGATTTTGCAAATTTAGTAGATTTAGATATTTTTGCACTTGT
CTGCGAAGATAAACGCGCTGTGCTTGTAAAATTCTTTATGCGTAATGGCAAAATTATCTCAAGTGCGACACAAAATCTTA
AAAGTGAATTAGGATTTGATAGTTTAAGCATTTATAAACAGGCACTAATTAACCACTACTCTAACACCCTTCCGCTAGTT
CCAAAACAAATTCTAATTCCCTTTGATTTAGGTGAAAGCACGCAAGAGTTGGAATACTTTTTGCAAAAAAAAGTTGGCAA
AAAAGTCCAAATCCACTTCCCAAAAAGTGGTGATAAAAAACGCCTATGCGAGCTTGCAATACAGAATGGAAAAGAGATTT
TACGCCTAGAACAAAATGATAATGAAGAAATTTTTAACGCCTTAAAAACGCTCTTTTGCCTACAAAATACGCCCTATCGC
TTTGAAGTTTTTGATACCTCTCACCACAAAGGCACACAATGCGTTGGAGCAATGGTTGTGTATGATGGCTTGGATTTTAT
CAAGGAATCTTATCGCCATTATTTACTAGAAGGCAAAGATGAATACACACAAATGCGTGAAATGCTAACACGGCGCATAC
AAGATTTTCAAAAAGAATCCCCGCCTGATTTATGGGTGCTTGATGGGGGGGCTGGACAGATTAATCTTGCAAAAGAGTTG
CTAGAGAGTGCGGGAGTTAATTTAGAAGTTATAGGGATTGCAAAAGAGAAGATTGATAGCAAGACTCACCGCGCAAAAGG
CGGTGCAAAAGACATTTTAAGAGATGAAAATTTAAAGGAATATCGCCTAAGTATGAGCGATAAACGCTTGCAATTTTTAC
AAAAATTGCGCGATGAAGCACATCGCTTTGCAATCACCTTTCACCAAAAGCAAAAGCAAAAAACAATGCAACACTCTAAA
CTTTTAAGCATTAAAGGCATAGGCAAAGCTATCCAAAACAAGCTCTTAGCCTATTTTGGAAGTTTTGAAGCCATTGAAAA
GGCAGACTTAGATGAGCTTGAAAAAGTGCTATCAAAAACCTTTGCTAAATCCGTTTTTAATGCGCTTAGAAGTTTCCAAA
ATAACGCACAGCACTGA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(391-545)

GIY-YIG catalytic domain (GIY-YIG)

(23-105)

UvrB/uvrC motif (UVR)

(212-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

57.022

95.631

0.545