Detailed information NTG0049596

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SSGZ1_RS07655
• Genome accession: NC_017617
• Coordinates: 1543052..1544101 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis GZ1
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1538052..1549101

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSGZ1_RS07635 (SSGZ1_1505)	nadE	1538458..1539282 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
SSGZ1_RS07640 (SSGZ1_1506)	-	1540578..1541105 (-)	528	WP_012027591.1	VanZ family protein	-
SSGZ1_RS07645 (SSGZ1_1507)	rlmN	1541102..1542214 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SSGZ1_RS07650 (SSGZ1_1508)	-	1542223..1542864 (-)	642	WP_012027595.1	YutD family protein	-
SSGZ1_RS07655 (SSGZ1_1509)	sepM	1543052..1544101 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
SSGZ1_RS07660 (SSGZ1_1510)	coaD	1544088..1544576 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
SSGZ1_RS07665 (SSGZ1_1511)	rsmD	1544566..1545105 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SSGZ1_RS07670 (SSGZ1_1512)	-	1545413..1546135 (-)	723	WP_012027598.1	lipoprotein	-
SSGZ1_RS07675 (SSGZ1_1513)	-	1546192..1546578 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
SSGZ1_RS07680 (SSGZ1_1514)	-	1546578..1546796 (-)	219	WP_004194736.1	YqgQ family protein	-
SSGZ1_RS07685 (SSGZ1_1515)	-	1547104..1547706 (-)	603	WP_012027601.1	response regulator transcription factor	-
SSGZ1_RS07690 (SSGZ1_1516)	-	1547703..1548797 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=49596 SSGZ1_RS07655 WP_012775295.1 1543052..1544101(-) (sepM) [Streptococcus suis GZ1]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=49596 SSGZ1_RS07655 WP_012775295.1 1543052..1544101(-) (sepM) [Streptococcus suis GZ1]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605