Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   SPYALAB49_RS08595 Genome accession   NC_017596
Coordinates   1727918..1728631 (+) Length   237 a.a.
NCBI ID   WP_014635777.1    Uniprot ID   -
Organism   Streptococcus pyogenes Alab49     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1722918..1733631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYALAB49_RS08585 (SPYALAB49_001764) treC 1723987..1725615 (-) 1629 WP_014635775.1 alpha,alpha-phosphotrehalase -
  SPYALAB49_RS08590 (SPYALAB49_001765) treP 1725683..1727707 (-) 2025 WP_014635776.1 PTS system trehalose-specific EIIBC component -
  SPYALAB49_RS08595 (SPYALAB49_001766) treR 1727918..1728631 (+) 714 WP_014635777.1 trehalose operon repressor Regulator
  SPYALAB49_RS08600 - 1728910..1729241 (-) 332 Protein_1652 winged helix-turn-helix transcriptional regulator -
  SPYALAB49_RS08605 (SPYALAB49_001770) - 1729427..1730284 (+) 858 Protein_1653 VOC family protein -
  SPYALAB49_RS08610 (SPYALAB49_001771) yaaA 1730326..1731057 (+) 732 WP_014635779.1 peroxide stress protein YaaA -
  SPYALAB49_RS08615 (SPYALAB49_001772) nrdG 1731231..1731845 (-) 615 WP_002982219.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  SPYALAB49_RS08620 (SPYALAB49_001773) - 1731860..1732354 (-) 495 WP_011055085.1 GNAT family N-acetyltransferase -
  SPYALAB49_RS08625 (SPYALAB49_001774) - 1732363..1733298 (-) 936 WP_002992828.1 Gfo/Idh/MocA family protein -
  SPYALAB49_RS09845 (SPYALAB49_001775) - 1733327..1733473 (-) 147 WP_002982210.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27548.73 Da        Isoelectric Point: 9.7515

>NTDB_id=49554 SPYALAB49_RS08595 WP_014635777.1 1727918..1728631(+) (treR) [Streptococcus pyogenes Alab49]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIRHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTRGIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=49554 SPYALAB49_RS08595 WP_014635777.1 1727918..1728631(+) (treR) [Streptococcus pyogenes Alab49]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAGACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTAGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACGCGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGGAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTCTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

67.949

98.734

0.671

Multiple sequence alignment