Detailed information NTG0049534

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SPYALAB49_RS04335
• Genome accession: NC_017596
• Coordinates: 860049..860885 (+)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes Alab49
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 855049..865885

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYALAB49_RS04305 (SPYALAB49_000875)	-	855531..855971 (+)	441	WP_009880949.1	hypothetical protein	-
SPYALAB49_RS04310 (SPYALAB49_000876)	-	856021..856932 (-)	912	WP_002984631.1	diacylglycerol kinase family protein	-
SPYALAB49_RS04315 (SPYALAB49_000877)	-	857049..857699 (-)	651	WP_002984629.1	hemolysin III family protein	-
SPYALAB49_RS04320 (SPYALAB49_000878)	-	857696..858136 (-)	441	WP_002984627.1	DUF1836 domain-containing protein	-
SPYALAB49_RS04325 (SPYALAB49_000879)	ylqF	858355..859203 (+)	849	WP_014635467.1	ribosome biogenesis GTPase YlqF	-
SPYALAB49_RS04330 (SPYALAB49_000880)	-	859193..859984 (+)	792	WP_002995007.1	ribonuclease HII	-
SPYALAB49_RS04335 (SPYALAB49_000881)	dprA	860049..860885 (+)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
SPYALAB49_RS04340 (SPYALAB49_000882)	topA	860992..863121 (+)	2130	WP_002984618.1	type I DNA topoisomerase	-
SPYALAB49_RS04345 (SPYALAB49_000883)	-	863240..864373 (+)	1134	WP_000564846.1	ISAs1-like element IS1548 family transposase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=49534 SPYALAB49_RS04335 WP_002995009.1 860049..860885(+) (dprA) [Streptococcus pyogenes Alab49]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=49534 SPYALAB49_RS04335 WP_002995009.1 860049..860885(+) (dprA) [Streptococcus pyogenes Alab49]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367