Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   SALIVA_RS03035 Genome accession   NC_017595
Coordinates   618431..620701 (-) Length   756 a.a.
NCBI ID   WP_014634121.1    Uniprot ID   -
Organism   Streptococcus salivarius JIM8777     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 613431..625701
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVA_RS03005 (SALIVA_0609) - 613813..614433 (+) 621 WP_002885892.1 DUF3862 domain-containing protein -
  SALIVA_RS03010 (SALIVA_0610) - 614516..615199 (+) 684 WP_014634117.1 TVP38/TMEM64 family protein -
  SALIVA_RS03015 (SALIVA_0611) - 615177..616412 (+) 1236 WP_014634118.1 aminoacyltransferase -
  SALIVA_RS03020 (SALIVA_0612) - 616510..617472 (+) 963 WP_014634119.1 Gfo/Idh/MocA family protein -
  SALIVA_RS03025 (SALIVA_0613) - 617518..617820 (-) 303 WP_002885967.1 DUF1827 family protein -
  SALIVA_RS03030 (SALIVA_0614) - 617830..618288 (-) 459 WP_014634120.1 NUDIX hydrolase -
  SALIVA_RS03035 (SALIVA_0615) clpE 618431..620701 (-) 2271 WP_014634121.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  SALIVA_RS03040 (SALIVA_0616) argF 620944..621924 (+) 981 WP_014634122.1 ornithine carbamoyltransferase -
  SALIVA_RS03045 (SALIVA_0617) - 621993..622223 (+) 231 WP_002885970.1 DUF1797 family protein -
  SALIVA_RS03050 (SALIVA_0618) - 622537..623217 (+) 681 WP_002886081.1 amino acid ABC transporter permease -
  SALIVA_RS03055 (SALIVA_0619) - 623217..623951 (+) 735 WP_002886191.1 amino acid ABC transporter ATP-binding protein -
  SALIVA_RS03060 (SALIVA_0620) - 624123..624599 (+) 477 WP_014634123.1 ferrous iron transport protein A -

Sequence

Protein


Download         Length: 756 a.a.        Molecular weight: 84051.11 Da        Isoelectric Point: 5.0564

>NTDB_id=49460 SALIVA_RS03035 WP_014634121.1 618431..620701(-) (clpE) [Streptococcus salivarius JIM8777]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQNCYKIMKSDPENPLNQFNQTGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGGNTQGPGRPGGPRQQAPQQPQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGSVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNAG
DGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAI
TAAAELSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
KQTIKDQDMPIITEKHIEAIVEQKTNIPVGDLKEKEQSQLLSLADDLKSHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEV
EKAHPDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGATRENRTNSVLNQLGDFFSSEFMNRFD
GIIEFSALSKENLLTIVDLMLDNVNQRLANNGIHLSVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLENPN
EKDLKAVMTSKGHITIKSAKKAEKTTQKAETAKETD

Nucleotide


Download         Length: 2271 bp        

>NTDB_id=49460 SALIVA_RS03035 WP_014634121.1 618431..620701(-) (clpE) [Streptococcus salivarius JIM8777]
ATGCTCTGTCAAAACTGTAACCTTAATGAAGCTAGTATTCATTTGTATACCAATGTAAATGGTAATCAGCAACAAGTTGA
CCTCTGTCAAAATTGTTATAAAATCATGAAATCTGACCCAGAGAACCCCCTTAATCAATTCAATCAAACTGGAGGTTCCA
ACTTCTTCGATGATTTCTTCAGCGACCTAAATAACTTCCGTTCTTCTAACGGTGATCTTCCCAATACACCTCCAACACAA
GAAGGTGGTAACCGAGGAAACGGTGGCAATACACAAGGGCCAGGCCGTCCAGGAGGACCACGCCAACAAGCTCCTCAACA
GCCACAAGGTCTTCTTGAAGAGTTCGGCATTAACATCACTGACATCGCTCGTCGTGGAGACATCGATCCAGTCATTGGTC
GTGACGAGGAAATCATTCGTGTCATCGAAATTCTTAACCGCCGTACCAAGAACAATCCCGTCCTCATCGGTGAACCCGGT
GTCGGTAAGACTGCTGTCGTTGAAGGACTAGCTCAAAAAATTGTAGATGGTAGCGTTCCTCAAAAACTCCAAGGCAAACA
AGTCATCCGTCTTGATGTGGTCAGCTTGGTTCAAGGAACTGGTATCCGAGGCCAATTTGAAGAACGCATGCAAAAACTCA
TGGAAGAAATTCGTCAACGTCAGGATGTTATCCTATTTATTGATGAAATCCATGAAATCGTAGGAGCTGGTAATGCTGGA
GATGGCAATATGGATGCTGGAAACATCCTAAAACCTGCCCTTGCTCGTGGGGAACTTCAACTGGTCGGAGCAACAACACT
CAACGAATACCGCATCATCGAAAAAGATGCTGCCCTAGAGCGTCGTATGCAACCAGTTAAGGTTGACGAACCAACGGTTG
AGGAAACCATCACTATTTTGCGGGGTATTCAACCTAAATATCAAGACTACCACCACGTCAAATATACGGATGAAGCGATT
ACTGCAGCTGCAGAATTGTCCAACCGCTACATTCAAGACCGTTTCTTGCCAGACAAGGCCATCGACCTTCTTGATGAAGC
TGGTTCGAAGATGAACTTGACCCTCAATTTTGTTGATCCTAAAGATATCGACAAACGTTTGATTGAGGCTGAAAACCTCA
AGGCTCAAGCTACTCGTGACGAAGACTTTGAAAAAGCTGCCTATTTCCGTGATCAAATTGCCAAATACAAGGAAATGCAA
AAACAAACCATCAAAGACCAAGATATGCCTATCATCACAGAAAAACATATCGAAGCCATTGTGGAACAAAAAACCAATAT
TCCTGTCGGTGATTTGAAAGAAAAAGAACAATCACAACTTCTTAGTCTTGCTGATGATCTTAAATCACATGTTATTGGAC
AAGATGCCGCAGTTGATAAGATTGCCAAAGCCATCCGTCGTAATCGTGTTGGATTGGGTGCACCAAATCGCCCAATTGGT
AGCTTCCTCTTCGTAGGTCCTACAGGAGTCGGTAAAACTGAACTCTCTAAACAATTGGCTATTGAACTCTTTGGTTCAGC
TGACAGTATGATTCGTTTCGACATGTCAGAATACATGGAAAAACACGCCGTTGCCAAATTGGTCGGTGCCCCTCCAGGAT
ATGTCGGTTACGACGAAGCTGGTCAGTTAACTGAAAAAGTCCGCCGTAATCCTTATTCACTCATTCTTCTGGATGAGGTT
GAAAAAGCTCACCCAGACGTTCTTCACATGTTCCTCCAAGTTCTTGACGACGGTCGCTTGACTGATGGTCAAGGGCGAAC
TGTAAGTTTCAAGGATACCATCATCATCATGACTTCAAATGCCGGTACAGGTAAAGTTGAAGCTAGCGTTGGCTTTGGAG
CTACTCGTGAAAATCGTACCAATTCTGTTCTTAACCAACTTGGAGATTTCTTCAGTTCTGAATTTATGAACCGCTTTGAC
GGTATTATCGAATTCTCTGCCCTTAGCAAAGAAAATCTCCTTACTATCGTGGACCTCATGCTTGATAATGTCAACCAACG
CTTGGCTAACAACGGTATCCACCTCAGTGTAACTGAGAAAGTTAAGGAAAAATTGGTTGACCTTGGTTACGATCCTAAGA
TGGGTGCTCGACCACTACGTCGTACCATCCAAGATCACATTGAAGATGCTATTACTGACTTCTACCTTGAAAATCCAAAT
GAAAAAGATCTCAAGGCTGTCATGACTTCAAAAGGCCACATCACCATTAAGTCTGCTAAAAAAGCTGAAAAAACTACTCA
GAAAGCTGAGACAGCAAAAGAAACTGATTAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(292-390)

AAA domain (Cdc48 subfamily) (AAA_2)

(477-640)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(648-721)

ATPase family associated with various cellular activities (AAA) (AAA)

(154-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.505

99.471

0.851
  clpE Streptococcus pneumoniae Rx1

83.134

99.603

0.828
  clpE Streptococcus pneumoniae D39

83.134

99.603

0.828
  clpE Streptococcus pneumoniae R6

83.134

99.603

0.828
  clpE Streptococcus pneumoniae TIGR4

83.001

99.603

0.827
  clpC Lactococcus lactis subsp. cremoris KW2

76.72

100

0.767
  clpC Bacillus subtilis subsp. subtilis str. 168

51.698

85.714

0.443
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.201

87.037

0.402
  clpC Streptococcus pneumoniae Rx1

47.987

82.143

0.394
  clpC Streptococcus pneumoniae D39

47.987

82.143

0.394
  clpC Streptococcus pneumoniae TIGR4

47.826

82.143

0.393
  clpC Streptococcus thermophilus LMD-9

46.56

82.672

0.385
  clpC Streptococcus thermophilus LMG 18311

46.24

82.672

0.382
  clpC Streptococcus mutans UA159

46.067

82.407

0.38

Multiple sequence alignment