Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   IM723_RS05605 Genome accession   NZ_CP063275
Coordinates   1072940..1073821 (-) Length   293 a.a.
NCBI ID   WP_011681210.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain DMST-H2     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1067940..1078821
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IM723_RS05580 vicR 1068645..1069352 (-) 708 WP_173940375.1 response regulator YycF Regulator
  IM723_RS05585 - 1069879..1070646 (+) 768 WP_022096757.1 amino acid ABC transporter ATP-binding protein -
  IM723_RS05590 - 1070658..1071491 (+) 834 WP_002953142.1 transporter substrate-binding domain-containing protein -
  IM723_RS05595 - 1071509..1072207 (+) 699 WP_002953144.1 amino acid ABC transporter permease -
  IM723_RS05600 - 1072219..1072869 (+) 651 WP_211836788.1 amino acid ABC transporter permease -
  IM723_RS05605 endA 1072940..1073821 (-) 882 WP_011681210.1 DNA/RNA non-specific endonuclease Machinery gene
  IM723_RS05610 - 1073883..1074071 (-) 189 WP_011226090.1 DNA-directed RNA polymerase subunit beta -
  IM723_RS05615 murA 1074073..1075344 (-) 1272 WP_211836789.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  IM723_RS05620 - 1075414..1075650 (-) 237 WP_002946959.1 DUF1146 family protein -
  IM723_RS05625 galE 1075838..1076851 (-) 1014 WP_002946961.1 UDP-glucose 4-epimerase GalE -
  IM723_RS05630 - 1076866..1077321 (-) 456 WP_211836790.1 DUF4832 domain-containing protein -

Sequence

Protein


Download         Length: 293 a.a.        Molecular weight: 31773.50 Da        Isoelectric Point: 10.1789

>NTDB_id=494167 IM723_RS05605 WP_011681210.1 1072940..1073821(-) (endA) [Streptococcus thermophilus strain DMST-H2]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide


Download         Length: 882 bp        

>NTDB_id=494167 IM723_RS05605 WP_011681210.1 1072940..1073821(-) (endA) [Streptococcus thermophilus strain DMST-H2]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(101-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

72.803

81.57

0.594
  endA Streptococcus pneumoniae D39

72.803

81.57

0.594
  endA Streptococcus pneumoniae R6

72.803

81.57

0.594
  endA Streptococcus pneumoniae TIGR4

72.803

81.57

0.594