Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   SSAL_RS07045 Genome accession   NC_017594
Coordinates   1529297..1531567 (+) Length   756 a.a.
NCBI ID   WP_045001866.1    Uniprot ID   A0AB35IVR6
Organism   Streptococcus salivarius 57.I     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1524297..1536567
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSAL_RS07015 (Ssal_01550) - 1524650..1525126 (-) 477 WP_004182941.1 ferrous iron transport protein A -
  SSAL_RS07020 (Ssal_01551) tnpA 1525378..1525851 (-) 474 WP_002891962.1 IS200/IS605 family transposase -
  SSAL_RS07025 (Ssal_01552) - 1526047..1526781 (-) 735 WP_004182942.1 amino acid ABC transporter ATP-binding protein -
  SSAL_RS07030 (Ssal_01553) - 1526781..1527461 (-) 681 WP_002886081.1 amino acid ABC transporter permease -
  SSAL_RS07035 (Ssal_01554) - 1527775..1528005 (-) 231 WP_002885970.1 DUF1797 family protein -
  SSAL_RS07040 (Ssal_01556) argF 1528074..1529054 (-) 981 WP_014633411.1 ornithine carbamoyltransferase -
  SSAL_RS07045 (Ssal_01557) clpE 1529297..1531567 (+) 2271 WP_045001866.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  SSAL_RS07050 (Ssal_01558) - 1531710..1532168 (+) 459 WP_014633413.1 NUDIX hydrolase -
  SSAL_RS07055 (Ssal_01559) - 1532178..1532480 (+) 303 WP_002885967.1 DUF1827 family protein -
  SSAL_RS07060 (Ssal_01560) - 1532526..1533488 (-) 963 WP_014633414.1 Gfo/Idh/MocA family oxidoreductase -
  SSAL_RS07065 (Ssal_01562) - 1533568..1534251 (-) 684 WP_014633415.1 VTT domain-containing protein -
  SSAL_RS07070 (Ssal_01563) - 1534334..1534954 (-) 621 WP_002885892.1 DUF3862 domain-containing protein -

Sequence

Protein


Download         Length: 756 a.a.        Molecular weight: 84013.11 Da        Isoelectric Point: 5.0564

>NTDB_id=49411 SSAL_RS07045 WP_045001866.1 1529297..1531567(+) (clpE) [Streptococcus salivarius 57.I]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQNCYKIMKSDPENPLNQFNQTGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGGNTQGPGRPGGPRQQAPQQPQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGSVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNAG
DGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAI
TAAAELSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
KQTIKDQDMPVITEKHIEAIVEQKTNIPVGDLKEKEQSQLLSLADDLKSHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEV
EKAHPDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAARENRTNSVLNQLGDFFSPEFMNRFD
GIIEFSALSKENLLTIVDLMLDNVNQRLANNGIHLSVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLENPN
EKDLKAVMTSKGHITIKSAKKAEKATQKAETPKETD

Nucleotide


Download         Length: 2271 bp        

>NTDB_id=49411 SSAL_RS07045 WP_045001866.1 1529297..1531567(+) (clpE) [Streptococcus salivarius 57.I]
ATGCTCTGTCAAAACTGTAACCTTAATGAAGCTAGTATTCATTTGTATACCAATGTAAATGGTAATCAGCAACAAGTTGA
CCTCTGTCAAAATTGTTATAAAATCATGAAATCTGATCCAGAGAACCCCCTCAATCAATTCAATCAAACAGGAGGTTCCA
ACTTCTTCGACGATTTCTTCAGCGACCTAAATAACTTCCGTTCTTCTAACGGCGATCTTCCCAATACACCTCCAACACAA
GAAGGTGGTAACCGAGGAAACGGTGGCAATACACAAGGACCAGGACGTCCAGGAGGACCACGCCAACAAGCTCCTCAACA
GCCACAAGGTCTTCTTGAAGAGTTCGGCATTAACATCACTGACATCGCTCGTCGTGGAGACATTGATCCTGTTATTGGTC
GTGACGAGGAAATCATTCGTGTCATCGAAATTCTTAACCGCCGTACCAAGAACAACCCCGTCCTCATCGGTGAACCCGGT
GTCGGTAAGACTGCTGTCGTTGAAGGTCTAGCTCAAAAAATCGTTGACGGTAGCGTGCCACAAAAACTCCAAGGCAAACA
AGTCATTCGTCTCGATGTGGTCAGCCTGGTTCAAGGGACTGGTATCCGTGGCCAATTTGAAGAACGCATGCAAAAACTCA
TGGAAGAAATTCGTCAACGTCAGGATGTTATCCTATTTATTGATGAAATCCATGAAATCGTAGGAGCTGGTAATGCCGGG
GATGGCAATATGGATGCTGGAAACATCCTAAAACCTGCCCTTGCTCGTGGGGAACTTCAACTGGTCGGAGCAACTACACT
CAACGAATACCGCATCATCGAAAAAGATGCTGCCCTAGAGCGTCGTATGCAACCAGTTAAGGTTGACGAACCAACGGTTG
AGGAAACCATCACTATTTTGCGTGGTATCCAACCTAAATATCAAGACTACCACCATGTCAAATATACAGACGAAGCTATT
ACTGCAGCTGCAGAATTGTCCAACCGCTACATTCAAGACCGTTTCTTGCCAGACAAGGCCATTGACCTTCTCGATGAAGC
TGGTTCTAAGATGAACTTGACCCTCAATTTTGTTGATCCTAAAGATATCGACAAACGTTTGATTGAGGCTGAAAACCTCA
AGGCTCAAGCTACTCGTGACGAAGACTTTGAAAAAGCTGCCTATTTCCGTGATCAAATTGCTAAATACAAGGAAATGCAA
AAACAAACCATCAAAGACCAAGATATGCCTGTCATCACAGAAAAACATATCGAAGCCATTGTGGAACAAAAAACCAATAT
TCCTGTCGGTGATTTGAAAGAAAAAGAACAATCACAACTTCTTAGTCTTGCTGATGATCTTAAATCACATGTTATTGGAC
AAGATGCAGCAGTTGATAAGATTGCCAAAGCCATCCGTCGTAATCGTGTTGGATTGGGTGCACCAAATCGCCCAATTGGT
AGCTTCCTCTTCGTAGGTCCTACAGGAGTCGGTAAAACTGAACTCTCTAAACAATTGGCTATTGAACTCTTTGGTTCAGC
TGACAGTATGATTCGTTTCGACATGTCAGAATACATGGAAAAACATGCTGTCGCTAAATTGGTCGGTGCCCCTCCAGGAT
ACGTTGGTTACGACGAAGCTGGTCAGTTAACTGAAAAAGTCCGCCGTAATCCATATTCACTCATTCTTCTGGATGAGGTT
GAAAAAGCTCACCCAGACGTTCTTCACATGTTCCTCCAAGTTCTTGACGACGGTCGCTTGACTGATGGTCAAGGGCGAAC
TGTAAGTTTCAAGGATACCATTATCATCATGACTTCAAATGCGGGTACAGGTAAAGTTGAAGCTAGCGTTGGCTTTGGAG
CTGCCCGTGAAAATCGTACCAATTCTGTTCTTAACCAGCTTGGAGATTTCTTCAGCCCTGAATTCATGAACCGATTTGAT
GGTATTATCGAATTCTCTGCCCTTAGCAAGGAGAATCTCCTTACTATCGTTGACCTCATGCTTGATAATGTCAACCAACG
CTTGGCTAACAATGGTATCCACCTCAGTGTAACTGAGAAAGTTAAGGAAAAATTGGTTGACCTTGGTTACGATCCTAAGA
TGGGGGCTCGACCACTACGTCGTACCATCCAGGACCATATTGAAGACGCTATTACTGACTTCTACCTTGAAAACCCAAAT
GAAAAAGATCTCAAGGCGGTCATGACTTCAAAAGGCCATATCACCATTAAGTCTGCTAAAAAAGCTGAAAAAGCTACTCA
GAAAGCTGAAACACCAAAAGAAACTGATTAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(154-274)

AAA lid domain (AAA_lid_9)

(292-390)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(648-721)

AAA domain (Cdc48 subfamily) (AAA_2)

(477-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.771

99.471

0.853
  clpE Streptococcus pneumoniae Rx1

83.267

99.603

0.829
  clpE Streptococcus pneumoniae D39

83.267

99.603

0.829
  clpE Streptococcus pneumoniae R6

83.267

99.603

0.829
  clpE Streptococcus pneumoniae TIGR4

83.267

99.603

0.829
  clpC Lactococcus lactis subsp. cremoris KW2

76.741

100

0.772
  clpC Bacillus subtilis subsp. subtilis str. 168

51.852

85.714

0.444
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.037

86.772

0.399
  clpC Streptococcus pneumoniae Rx1

47.36

82.672

0.392
  clpC Streptococcus pneumoniae D39

47.36

82.672

0.392
  clpC Streptococcus pneumoniae TIGR4

47.2

82.672

0.39
  clpC Streptococcus thermophilus LMD-9

47.04

82.672

0.389
  clpC Streptococcus thermophilus LMG 18311

46.72

82.672

0.386
  clpC Streptococcus mutans UA159

46.486

82.804

0.385

Multiple sequence alignment