Detailed information NTG0049390

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SSAL_RS02265
• Genome accession: NC_017594
• Coordinates: 442082..444322 (+)
• Length: 746 a.a.
• NCBI ID: WP_013991033.1
• Uniprot ID: A0AAP3Q6Q7
• Organism: Streptococcus salivarius 57.I
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 437082..449322

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSAL_RS02240 (Ssal_00489)	-	438382..438651 (-)	270	WP_013991038.1	GIY-YIG nuclease family protein	-
SSAL_RS02245 (Ssal_00490)	-	438655..439419 (-)	765	WP_013991037.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
SSAL_RS02250 (Ssal_00491)	-	439469..440404 (-)	936	WP_045002039.1	polysaccharide deacetylase family protein	-
SSAL_RS02255 (Ssal_00492)	-	440534..441289 (+)	756	WP_013991035.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
SSAL_RS02260 (Ssal_00493)	comEA	441397..442092 (+)	696	WP_014632740.1	helix-hairpin-helix domain-containing protein	Machinery gene
SSAL_RS02265 (Ssal_00495)	comEC/celB	442082..444322 (+)	2241	WP_013991033.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SSAL_RS02270 (Ssal_00497)	-	444408..445670 (+)	1263	WP_013991032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
SSAL_RS02275 (Ssal_00498)	-	445736..446281 (+)	546	WP_013991031.1	GNAT family N-acetyltransferase	-
SSAL_RS02280 (Ssal_00499)	spxR	446274..447554 (+)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
SSAL_RS02285 (Ssal_00500)	-	447595..448455 (+)	861	WP_004183173.1	methionyl aminopeptidase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84531.46 Da
• Isoelectric Point: 9.8651

>NTDB_id=49390 SSAL_RS02265 WP_013991033.1 442082..444322(+) (comEC/celB) [Streptococcus salivarius 57.I]
MWLKKAPINLFSLALLIAALYFTVFVTNVYAIGTFVFLMVCFLKHHWKNKAALKLVGIVGSFFLVYFLFLHHKATIQDKQ
APAEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKIKLSPATGQRNFQGFNYQSY
LASQGIYRMAQIERLDYVVSQKSLSPLAFFHQLRRRALVHIQTHFPSPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIILLPFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLLFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICMSLVLSLGILPFLTYYYGTFQPVSLILTAIFSIVFDNFLLPVLT
VFFALSGLVIFSQINPLFEWMETFLTWIQSWIGQPLILGKPSLLQFSLMIAVLVMLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEGSQTSNAEKTLIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKRPVHTLKAGDKLPMMGSKLQVLYPNKIGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMASYPTLRASVLKAGHHGSKGSSSEAFLDQLHPSLALVSAGENNRYKHPNDETLERFKQRH
IKVLRTDKDGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=49390 SSAL_RS02265 WP_013991033.1 442082..444322(+) (comEC/celB) [Streptococcus salivarius 57.I]
ATGTGGCTTAAAAAGGCTCCAATCAATCTTTTTTCCTTGGCTCTGTTAATAGCTGCTCTTTATTTTACGGTTTTTGTCAC
TAATGTTTATGCTATTGGGACTTTTGTCTTTCTTATGGTCTGTTTTTTGAAACATCATTGGAAGAATAAGGCTGCCCTAA
AGTTGGTGGGAATTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTACACCACAAAGCTACCATACAAGATAAACAA
GCTCCTGCTGAAATCAATCAGGTGACTCTGGTTGCTGATACGTTATCGGTTAATGGTGAGCAATTATCAGCTATCGGAAA
GGCAAAGGGACAAACTTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTTAAGACTACTAGCCAAA
CGCTGGTATTAAAGGGGAAAATAAAGTTATCCCCAGCAACTGGTCAACGTAATTTTCAAGGGTTCAATTATCAGTCTTAT
CTAGCCAGCCAAGGTATTTATCGAATGGCTCAGATTGAGCGCTTGGATTATGTGGTGTCTCAAAAATCTCTATCTCCCTT
AGCTTTTTTCCATCAATTGAGGAGAAGGGCTTTGGTTCATATCCAGACACATTTTCCTAGTCCTATGAGACACTATATGA
CAGGCCTACTCTTTGGGTATTTGGATAAGGAGTTCGATGAGCAGAGTCAGCTTTACACAAGCCTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGCTATGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATTATCTTGCTACCTTTTTCCTTATGCTATGGCTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCC
TGATTCAAAGTTTGTTGGCGGAGTTTGGTATTAAAAAACTGGATAATATGGGAATAACCTTACTTCTATTGTTTCTCTTT
TTACCTCATTTTCTTTTAACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCTTTTTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTATGAGCTTGGTATTGAGTCTTGGGATTTTGCCTTTTCTAACTTACTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATATTTTCCATAGTCTTTGATAACTTTCTCTTGCCTGTCTTGACG
GTCTTCTTTGCCCTTTCAGGACTGGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGACCTTTTTGACTTG
GATACAATCTTGGATAGGCCAGCCATTAATTTTAGGGAAACCTAGTTTGTTACAGTTTAGCTTGATGATAGCTGTATTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGTTCAAAGGAAAAATGGCAGGAGGGGAGCCAGACGAGCAATG
CAGAGAAAACCTTGATTCCCTATCTACAGGCTAGAGGAGTGTCTCAAATTGATCACCTGGTCCTGACGCATACGGACACA
GACCATATTGGTGATTTGGAAGAAGTGGCCAAGAGGTTTAAGATTAAGGAAATCTGTGTCAGTCAGGGGGCTTTGACTAA
ACCTAGTTTTGTTAAAAGACTTCGGACCTTAAAACGACCAGTTCACACTCTAAAGGCTGGCGACAAATTACCCATGATGG
GAAGTAAGCTACAGGTTCTTTATCCCAATAAAATTGGTGATGGTGGTAACAACGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGCAGTTTTTTGTTTACTGGTGATTTGGAAAAAGAAGGAGAGGAGGAGCTGATGGCCAGCTATCCAACTTTAAG
GGCAAGCGTCCTCAAAGCTGGACACCACGGTTCAAAAGGCTCATCGTCTGAAGCTTTTTTGGATCAGTTGCACCCCTCCC
TTGCACTTGTTTCAGCTGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACATTAGAACGTTTTAAGCAACGTCAC
ATTAAGGTTTTACGAACAGATAAAGACGGAGCCATACGTTTTAAGGGTTGGTTTAAATGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (29-169)

• Competence protein (Competence) (216-462)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-694)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48.529	100	0.487
comEC/celB	Streptococcus mitis NCTC 12261	48.193	100	0.483
comEC/celB	Streptococcus pneumoniae Rx1	46.658	100	0.468
comEC/celB	Streptococcus pneumoniae D39	46.658	100	0.468
comEC/celB	Streptococcus pneumoniae R6	46.658	100	0.468
comEC/celB	Streptococcus pneumoniae TIGR4	46.524	100	0.466
comEC	Lactococcus lactis subsp. cremoris KW2	43.649	99.196	0.433