Detailed information NTG0493543

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: IMZ24_RS02405
• Genome accession: NZ_CP063157
• Coordinates: 478455..479618 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain GY65
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 473455..484618

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IMZ24_RS02385 (IMZ24_02385)	tuaH	473895..475091 (+)	1197	WP_032876154.1	teichuronic acid biosynthesis protein TuaH	-
IMZ24_RS02390 (IMZ24_02390)	-	475224..476300 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
IMZ24_RS02395 (IMZ24_02395)	-	476399..477580 (-)	1182	WP_032876157.1	LCP family protein	-
IMZ24_RS02400 (IMZ24_02400)	-	477585..478232 (-)	648	WP_007614107.1	YigZ family protein	-
IMZ24_RS02405 (IMZ24_02405)	degS	478455..479618 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
IMZ24_RS02410 (IMZ24_02410)	degU	479695..480384 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
IMZ24_RS02415 (IMZ24_02415)	-	480482..481330 (+)	849	WP_032876160.1	DegV family protein	-
IMZ24_RS02420 (IMZ24_02420)	comFA	481439..482824 (+)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
IMZ24_RS02425 (IMZ24_02425)	-	482882..483166 (+)	285	WP_003151389.1	late competence development ComFB family protein	-
IMZ24_RS02430 (IMZ24_02430)	comFC	483172..483861 (+)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
IMZ24_RS02435 (IMZ24_02435)	-	483935..484354 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=493543 IMZ24_RS02405 WP_007407484.1 478455..479618(+) (degS) [Bacillus velezensis strain GY65]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=493543 IMZ24_RS02405 WP_007407484.1 478455..479618(+) (degS) [Bacillus velezensis strain GY65]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951