Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   IMZ18_RS12185 Genome accession   NZ_CP063151
Coordinates   2246633..2247289 (-) Length   218 a.a.
NCBI ID   WP_014479448.1    Uniprot ID   A0A165B643
Organism   Bacillus subtilis subsp. subtilis strain CMIN-4     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2241633..2252289
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IMZ18_RS12160 (IMZ18_12160) spxH 2241844..2242743 (+) 900 WP_003245184.1 protease adaptor protein SpxH -
  IMZ18_RS12165 (IMZ18_12165) - 2243058..2243225 (+) 168 WP_003244944.1 hypothetical protein -
  IMZ18_RS12170 (IMZ18_12170) pepF 2243263..2245091 (-) 1829 Protein_2423 oligoendopeptidase F -
  IMZ18_RS12175 (IMZ18_12175) coiA 2245321..2246442 (-) 1122 WP_235091746.1 competence protein CoiA Machinery gene
  IMZ18_RS12180 (IMZ18_12180) - 2246516..2246638 (+) 123 WP_003245684.1 hypothetical protein -
  IMZ18_RS12185 (IMZ18_12185) mecA 2246633..2247289 (-) 657 WP_014479448.1 adaptor protein MecA Regulator
  IMZ18_RS12190 (IMZ18_12190) - 2247256..2247396 (-) 141 WP_119122854.1 hypothetical protein -
  IMZ18_RS12195 (IMZ18_12195) yjbE 2247566..2248222 (+) 657 WP_014479447.1 TerC family protein -
  IMZ18_RS12200 (IMZ18_12200) spx 2248265..2248660 (-) 396 WP_014476435.1 transcriptional regulator Spx -
  IMZ18_RS12205 (IMZ18_12205) yjbC 2248841..2249419 (-) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  IMZ18_RS12210 (IMZ18_12210) yjbB 2249583..2250800 (-) 1218 WP_072592593.1 MFS transporter -
  IMZ18_RS12215 (IMZ18_12215) oppF 2250908..2251825 (-) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25733.66 Da        Isoelectric Point: 4.1174

>NTDB_id=493478 IMZ18_RS12185 WP_014479448.1 2246633..2247289(-) (mecA) [Bacillus subtilis subsp. subtilis strain CMIN-4]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALEAIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=493478 IMZ18_RS12185 WP_014479448.1 2246633..2247289(-) (mecA) [Bacillus subtilis subsp. subtilis strain CMIN-4]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAGCGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A165B643

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995