Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   SPNINV200_RS09520 Genome accession   NC_017593
Coordinates   1803547..1804371 (-) Length   274 a.a.
NCBI ID   WP_001036789.1    Uniprot ID   -
Organism   Streptococcus pneumoniae INV200     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1798547..1809371
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPNINV200_RS09515 (SPNINV200_17740) - 1801925..1803256 (-) 1332 WP_000390043.1 hemolysin family protein -
  SPNINV200_RS09520 (SPNINV200_17750) endA 1803547..1804371 (-) 825 WP_001036789.1 DNA-entry nuclease EndA Machinery gene
  SPNINV200_RS09525 (SPNINV200_17760) - 1804410..1804598 (-) 189 WP_001813390.1 DNA-directed RNA polymerase subunit beta -
  SPNINV200_RS09530 (SPNINV200_17770) murA 1804591..1805874 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SPNINV200_RS09535 (SPNINV200_17780) - 1805898..1806128 (-) 231 WP_000250392.1 DUF1146 family protein -
  SPNINV200_RS09540 (SPNINV200_17790) sepM 1806186..1807223 (-) 1038 WP_000727278.1 SepM family pheromone-processing serine protease Regulator
  SPNINV200_RS09545 (SPNINV200_17800) coaD 1807207..1807695 (-) 489 WP_001280769.1 pantetheine-phosphate adenylyltransferase -
  SPNINV200_RS09550 (SPNINV200_17810) rsmD 1807685..1808224 (-) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SPNINV200_RS09555 (SPNINV200_17820) asnA 1808289..1809281 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29966.67 Da        Isoelectric Point: 10.1700

>NTDB_id=49341 SPNINV200_RS09520 WP_001036789.1 1803547..1804371(-) (endA) [Streptococcus pneumoniae INV200]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLNQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=49341 SPNINV200_RS09520 WP_001036789.1 1803547..1804371(-) (endA) [Streptococcus pneumoniae INV200]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAATCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.175

100

0.982
  endA Streptococcus pneumoniae D39

98.175

100

0.982
  endA Streptococcus pneumoniae R6

98.175

100

0.982
  endA Streptococcus pneumoniae TIGR4

98.175

100

0.982

Multiple sequence alignment