Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   A0Z60_RS03375 Genome accession   NZ_CP063087
Coordinates   673000..674856 (+) Length   618 a.a.
NCBI ID   WP_197550474.1    Uniprot ID   -
Organism   Helicobacter winghamensis strain 2015D-0170     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 668000..679856
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0Z60_RS03340 (A0Z60_03340) hemJ 668143..668574 (-) 432 WP_006802351.1 protoporphyrinogen oxidase HemJ -
  A0Z60_RS03345 (A0Z60_03345) - 668734..669372 (+) 639 WP_197550618.1 amino acid ABC transporter permease -
  A0Z60_RS03350 (A0Z60_03350) - 669377..670030 (+) 654 WP_197550471.1 amino acid ABC transporter permease -
  A0Z60_RS03355 (A0Z60_03355) - 670039..670776 (+) 738 WP_197550472.1 amino acid ABC transporter ATP-binding protein -
  A0Z60_RS03360 (A0Z60_03360) - 670785..670958 (-) 174 WP_197550473.1 hypothetical protein -
  A0Z60_RS03365 (A0Z60_03365) - 670969..672438 (-) 1470 WP_006802346.1 L-aspartate oxidase -
  A0Z60_RS03370 (A0Z60_03370) - 672544..672993 (+) 450 WP_232086817.1 hypothetical protein -
  A0Z60_RS03375 (A0Z60_03375) uvrC 673000..674856 (+) 1857 WP_197550474.1 excinuclease ABC subunit UvrC Machinery gene
  A0Z60_RS03380 (A0Z60_03380) - 674825..675310 (-) 486 WP_197550475.1 hypothetical protein -
  A0Z60_RS03385 (A0Z60_03385) cutA 675352..675678 (-) 327 WP_232086818.1 divalent cation tolerance protein CutA -
  A0Z60_RS03390 (A0Z60_03390) - 675687..675962 (-) 276 WP_006802340.1 hypothetical protein -
  A0Z60_RS03395 (A0Z60_03395) - 675964..676776 (-) 813 WP_197550476.1 hypothetical protein -
  A0Z60_RS03400 (A0Z60_03400) - 676785..677528 (-) 744 WP_006802338.1 DUF5644 domain-containing protein -
  A0Z60_RS03405 (A0Z60_03405) - 677572..678045 (-) 474 WP_006802337.1 hypothetical protein -
  A0Z60_RS03410 (A0Z60_03410) - 678047..679795 (-) 1749 WP_197550477.1 M3 family oligoendopeptidase -

Sequence

Protein


Download         Length: 618 a.a.        Molecular weight: 71020.45 Da        Isoelectric Point: 9.7197

>NTDB_id=492827 A0Z60_RS03375 WP_197550474.1 673000..674856(+) (uvrC) [Helicobacter winghamensis strain 2015D-0170]
MESNLKPLSQTLLETLKKIPNSSGVYHYFDTQGKLLYVGKAKNLKHRIKSYFRFTPNLAPAPNLSPRITQMVSQIAHLRY
IVVENENDALILENSLIKQLKPKYNVLLRDDKTYPYLCVDLQEDFPRILLTRKIFKKQGLRYFGPFSSGARDLLDSIYEI
FPLAQKESCKNGKKACLFYQIHRCLAPCEGKISTKDYAKILQNALECVENPKKILAPLEQKMLQLSQNLRFEEALILRDR
IAKIKNLTPLSSVDFANLVDLDIFALVCKDKRAVLVKFFMRNGKIISSATQNLKSELGFDSLSIYKQALINHYSNTLPLV
PKQILIPFDLGESTQELEYFLQEKVGKKVQIHFPKSGDKKRLCELAIQNGKEILRLEQNDNEEIFNALKTLFCLQNTPYR
FEVFDTSHHKGTQCVGAMVVYDGLDFIKESYRHYLLEGKDEYTQMREMLTRRIQDFQKESPPDLWVLDGGAGQINLAKEL
LESAGVNLEVIGIAKEKIDSKAHRAKGGAKDILRDENLKEYRLSMSDKRLQFLQKLRDEAHRFAITFHQKQKQKTMQHSK
LLSIKGIGKAIQNKLLAYFGSFEAIEKADLDELEKVLSKNLAKSVFNALRSFQNNAQH

Nucleotide


Download         Length: 1857 bp        

>NTDB_id=492827 A0Z60_RS03375 WP_197550474.1 673000..674856(+) (uvrC) [Helicobacter winghamensis strain 2015D-0170]
ATGGAATCTAACCTTAAGCCACTCTCACAAACACTACTAGAAACTTTAAAAAAGATTCCAAATTCTAGCGGTGTGTATCA
TTATTTTGACACGCAAGGCAAGTTGCTTTATGTGGGCAAGGCAAAGAATCTAAAACATCGCATTAAAAGTTATTTTCGTT
TCACTCCAAACTTAGCTCCCGCACCAAATTTAAGCCCAAGAATTACGCAAATGGTTAGTCAAATCGCACATTTACGCTAT
ATTGTTGTGGAGAACGAAAATGACGCGCTAATCTTAGAAAACTCCCTAATTAAGCAACTTAAGCCAAAATACAATGTGTT
ATTGCGCGATGATAAAACTTATCCGTATTTATGCGTGGATTTACAAGAAGATTTTCCGCGCATTTTACTCACTAGAAAAA
TTTTTAAAAAGCAAGGATTGCGCTATTTTGGACCTTTTTCAAGCGGTGCTAGGGATCTTTTGGATTCCATCTATGAAATT
TTCCCACTTGCACAAAAAGAATCGTGCAAAAATGGCAAAAAAGCCTGTCTTTTTTATCAAATCCATCGCTGTTTAGCTCC
CTGTGAAGGTAAAATTTCTACCAAAGACTATGCAAAGATTCTCCAAAATGCCTTAGAGTGCGTAGAAAATCCTAAAAAAA
TCCTAGCACCATTGGAGCAAAAAATGCTTCAACTCTCACAAAATTTACGCTTTGAAGAAGCTCTAATCTTGCGCGATAGG
ATTGCAAAAATTAAAAACCTAACCCCTTTATCTTCTGTGGATTTTGCAAATTTAGTAGATTTAGATATTTTTGCACTTGT
CTGCAAAGATAAACGCGCTGTGCTTGTAAAATTCTTTATGCGTAATGGCAAAATTATCTCAAGTGCGACACAAAATCTTA
AAAGTGAATTAGGATTTGATAGTTTAAGCATTTATAAACAGGCACTAATTAACCACTACTCTAACACCCTTCCGCTAGTT
CCAAAACAAATTCTAATTCCCTTTGATTTAGGTGAAAGCACGCAAGAGTTGGAATACTTTTTGCAAGAAAAAGTTGGCAA
AAAAGTCCAAATCCACTTCCCAAAAAGTGGTGATAAAAAACGCCTATGCGAGCTTGCAATACAGAATGGAAAAGAGATTT
TACGCCTAGAACAAAATGATAATGAAGAAATTTTTAACGCCTTAAAAACGCTCTTTTGCCTACAAAATACGCCCTATCGC
TTTGAAGTTTTTGATACCTCTCACCACAAAGGCACACAATGCGTTGGAGCAATGGTTGTGTATGATGGCTTGGATTTTAT
CAAGGAATCTTATCGCCATTATTTACTAGAAGGCAAAGATGAATACACACAAATGCGTGAAATGCTAACACGGCGCATAC
AAGATTTTCAAAAAGAATCCCCGCCTGATTTATGGGTGCTTGATGGGGGGGCTGGACAGATTAATCTTGCAAAAGAGTTG
CTAGAGAGTGCGGGAGTTAATTTAGAAGTTATAGGGATTGCAAAAGAGAAGATTGATAGCAAGGCTCACCGCGCAAAAGG
CGGTGCAAAAGACATTTTAAGAGATGAAAATTTAAAGGAATATCGCCTAAGTATGAGCGATAAACGCTTGCAATTTTTAC
AAAAATTGCGCGATGAAGCACATCGCTTTGCAATCACCTTTCACCAAAAGCAAAAGCAAAAAACAATGCAACACTCTAAA
CTTTTAAGCATTAAAGGCATAGGCAAAGCTATCCAAAACAAGCTCTTAGCCTATTTTGGAAGTTTTGAAGCCATTGAAAA
GGCAGACTTAGATGAGCTTGAAAAAGTGCTATCAAAAAACCTTGCCAAATCCGTTTTTAATGCGCTTAGAAGTTTCCAAA
ATAACGCACAGCACTGA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(391-545)

GIY-YIG catalytic domain (GIY-YIG)

(23-105)

UvrB/uvrC motif (UVR)

(212-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

57.095

95.793

0.547