Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HW245_RS09145 Genome accession   NZ_CP063086
Coordinates   1760619..1762460 (-) Length   613 a.a.
NCBI ID   WP_172586718.1    Uniprot ID   -
Organism   Helicobacter cinaedi strain 2017D-0197     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1755619..1767460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HW245_RS09130 (HW245_09120) - 1756937..1757626 (-) 690 WP_002956820.1 response regulator -
  HW245_RS09135 (HW245_09125) - 1757629..1759131 (-) 1503 WP_002956819.1 sensor histidine kinase -
  HW245_RS09140 (HW245_09130) - 1759141..1760622 (-) 1482 WP_014666647.1 hypothetical protein -
  HW245_RS09145 (HW245_09135) uvrC 1760619..1762460 (-) 1842 WP_172586718.1 excinuclease ABC subunit UvrC Machinery gene
  HW245_RS09150 (HW245_09140) - 1762504..1762962 (-) 459 WP_231900552.1 hypothetical protein -
  HW245_RS09155 (HW245_09145) - 1762954..1763202 (+) 249 WP_002956815.1 hypothetical protein -
  HW245_RS09160 (HW245_09150) nadB 1763203..1764648 (+) 1446 WP_104716683.1 L-aspartate oxidase -
  HW245_RS09165 (HW245_09155) rmuC 1764663..1766006 (-) 1344 WP_104716682.1 DNA recombination protein RmuC -
  HW245_RS09170 (HW245_09160) moaC 1766016..1766492 (-) 477 WP_104716681.1 cyclic pyranopterin monophosphate synthase MoaC -
  HW245_RS09175 (HW245_09165) mog 1766514..1767044 (-) 531 WP_014666653.1 molybdopterin adenylyltransferase -

Sequence

Protein


Download         Length: 613 a.a.        Molecular weight: 70757.33 Da        Isoelectric Point: 9.7723

>NTDB_id=492823 HW245_RS09145 WP_172586718.1 1760619..1762460(-) (uvrC) [Helicobacter cinaedi strain 2017D-0197]
MYSLLFTLQNLPTQPGIYQYFDKDDNLLYVGKAKNLKNRIKSYFSIHNDIITPKANLSQRIALMVSQVAKIHTLLTQNQE
DALILENSLIKSLKPKYNILLRDDKTYPYIYIDTSATFPRFEITRKVLQSKHIEYFGPFVSGARELLDSLYDALPLVQKK
SCLKGKKACIFHQIHKCPAPCENKISQSQYAEYITQAKAFIDDRKGLIEILESKMQILSHNLQFEEAAKIRDRIQKLKTL
KTQSIIDIMSGDYDIFLLDSAGQNHILMMLFIRNGRIVSSDFSFIHQEIHSQNLAQLYTQALLNHYKTPLPLPPKEILIP
HFDFQDKDEKDDLQKILQAQTQSHLKITQPQKGTKYNLLQLAKKNAQEILTLHTKEQKNAQNENTTLYALKDLCNLSQVP
YRIEIFDTSHHSGSHNVGGMVVYENGEFIRSAYRRFELHSSDEYSQMSEMLTRRAKKFESNPPPDLWLLDGGKAQINLAL
DILKSVGANVDIIAIAKMKYNAKAYRAKGNALDILRTQNAEFKLSTNDKRLQFCQKLRDEVHRYAITYHRNKKQKDIHKI
QIQKGSDMDSSYSKAQIKRLLDYFGSFHAIQNAPKEQIENALSRSFKSNKDSK

Nucleotide


Download         Length: 1842 bp        

>NTDB_id=492823 HW245_RS09145 WP_172586718.1 1760619..1762460(-) (uvrC) [Helicobacter cinaedi strain 2017D-0197]
ATATATAGTCTGCTTTTTACCCTGCAAAATCTCCCTACACAGCCCGGAATCTACCAATATTTTGATAAAGATGATAACTT
GCTCTATGTCGGCAAGGCTAAAAATCTAAAAAATCGCATAAAAAGCTATTTTTCTATCCATAATGACATCATCACGCCAA
AGGCTAACCTTAGCCAAAGAATAGCCCTTATGGTATCCCAAGTGGCTAAGATTCACACTTTACTTACACAAAACCAAGAA
GATGCCCTTATCCTTGAAAACTCCCTTATCAAAAGCCTAAAGCCAAAGTATAATATTCTTTTGCGTGATGATAAAACTTA
TCCTTATATTTATATTGATACTTCTGCTACTTTTCCACGATTTGAAATCACTCGCAAGGTGCTACAAAGTAAGCATATTG
AGTATTTTGGTCCTTTTGTGAGTGGAGCTAGAGAGCTGCTTGATAGTCTCTATGATGCCCTGCCCCTTGTGCAGAAAAAA
TCCTGCCTTAAAGGCAAAAAGGCGTGTATATTTCATCAGATTCATAAATGCCCTGCCCCTTGTGAAAATAAAATCTCTCA
AAGTCAATATGCAGAGTATATTACACAAGCAAAGGCGTTTATAGATGATAGAAAAGGACTTATAGAGATTTTAGAATCTA
AAATGCAGATACTCTCACACAATTTACAATTTGAAGAGGCAGCAAAGATACGAGATAGAATCCAAAAGCTAAAAACACTA
AAAACCCAATCTATTATTGATATTATGAGCGGAGATTATGATATTTTCCTGCTTGATTCAGCAGGGCAAAATCATATCCT
TATGATGCTTTTTATCCGCAATGGACGCATTGTCTCAAGTGATTTTTCATTTATCCACCAAGAGATTCACAGCCAAAACC
TAGCCCAACTCTACACCCAAGCCTTACTTAATCACTATAAAACCCCTCTTCCCTTGCCACCAAAGGAGATTCTTATCCCG
CATTTTGACTTCCAAGACAAAGATGAAAAAGATGATTTACAAAAGATTTTGCAAGCCCAAACACAAAGTCATCTCAAAAT
CACCCAACCACAAAAAGGCACAAAATATAACCTTTTGCAACTTGCTAAAAAGAACGCCCAAGAAATCCTAACTTTGCATA
CCAAAGAGCAAAAGAACGCCCAAAATGAAAACACCACTTTATACGCTCTAAAAGATTTATGCAATCTCTCTCAAGTGCCT
TATAGGATAGAGATCTTTGACACCTCTCATCATAGCGGAAGCCACAATGTAGGCGGAATGGTAGTGTATGAAAATGGCGA
GTTTATCCGCAGTGCTTACAGACGCTTTGAGCTTCATAGCAGTGATGAATACTCTCAAATGAGTGAAATGCTAACACGCA
GGGCAAAAAAATTTGAATCCAATCCGCCACCAGATTTATGGCTACTTGATGGGGGCAAGGCTCAAATCAACCTAGCACTT
GACATTCTAAAAAGTGTGGGGGCAAATGTAGATATTATCGCCATTGCCAAAATGAAATATAATGCCAAAGCCTATCGCGC
TAAAGGCAATGCCCTTGATATTTTACGCACACAAAATGCGGAGTTTAAACTTAGCACAAACGATAAAAGACTACAATTCT
GCCAAAAGCTCCGCGATGAAGTGCATAGATATGCTATCACTTATCATCGCAACAAAAAGCAAAAAGACATACACAAGATT
CAGATTCAAAAAGGAAGTGATATGGATAGCTCTTATAGCAAGGCTCAAATTAAACGACTTTTAGATTATTTTGGCTCATT
CCACGCCATTCAAAACGCTCCAAAAGAACAGATAGAAAATGCTCTTTCACGCTCTTTTAAAAGTAATAAAGATTCAAAAT
GA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(207-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(392-546)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

51.244

98.369

0.504