Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SPNOXC_RS02020 Genome accession   NC_017592
Coordinates   370484..371173 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae OXC141     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 365484..376173
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPNOXC_RS01995 (SPNOXC03680) gpsB 365593..365922 (+) 330 WP_000146522.1 cell division regulator GpsB -
  SPNOXC_RS02005 (SPNOXC03690) - 366408..367565 (+) 1158 WP_000711393.1 class I SAM-dependent RNA methyltransferase -
  SPNOXC_RS02010 (SPNOXC03700) mapZ 367578..368972 (+) 1395 WP_000039274.1 mid-cell-anchored protein MapZ -
  SPNOXC_RS02015 (SPNOXC03710) gndA 369048..370472 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  SPNOXC_RS02020 (SPNOXC03720) covR 370484..371173 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  SPNOXC_RS02025 (SPNOXC03730) cbpC 371272..372294 (+) 1023 WP_000771085.1 choline-binding protein CbpC -
  SPNOXC_RS02030 (SPNOXC03740) - 372313..373434 (+) 1122 WP_000771140.1 N-acetylmuramoyl-L-alanine amidase family protein -
  SPNOXC_RS02035 (SPNOXC03750) - 373552..374784 (-) 1233 WP_000765691.1 MFS transporter -
  SPNOXC_RS02040 (SPNOXC03760) - 374827..375702 (-) 876 WP_010963214.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=49222 SPNOXC_RS02020 WP_000518011.1 370484..371173(+) (covR) [Streptococcus pneumoniae OXC141]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=49222 SPNOXC_RS02020 WP_000518011.1 370484..371173(+) (covR) [Streptococcus pneumoniae OXC141]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAATG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment