Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   INV104_RS11160 Genome accession   NC_017591
Coordinates   2107538..2108200 (-) Length   220 a.a.
NCBI ID   WP_000649968.1    Uniprot ID   A0A098Z9B1
Organism   Streptococcus pneumoniae INV104     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2102538..2113200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INV104_RS11135 (INV104_19030) - 2102682..2102948 (-) 267 WP_001278167.1 Veg family protein -
  INV104_RS11140 (INV104_19040) dnaB 2102950..2104302 (-) 1353 WP_000852486.1 replicative DNA helicase -
  INV104_RS11145 (INV104_19050) rplI 2104346..2104798 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  INV104_RS11150 (INV104_19060) - 2104795..2106774 (-) 1980 WP_000715119.1 DHH family phosphoesterase -
  INV104_RS11155 (INV104_19070) hpf 2106910..2107458 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  INV104_RS11160 (INV104_19080) comFC/cflB 2107538..2108200 (-) 663 WP_000649968.1 ComF family protein Machinery gene
  INV104_RS11165 (INV104_19090) comFA/cflA 2108197..2109495 (-) 1299 WP_000867605.1 DEAD/DEAH box helicase Machinery gene
  INV104_RS11170 (INV104_19100) - 2109551..2110186 (+) 636 WP_000395754.1 YigZ family protein -
  INV104_RS11175 (INV104_19110) cysK 2110471..2111391 (+) 921 WP_000029860.1 cysteine synthase A -
  INV104_RS11180 (INV104_19120) - 2111466..2112004 (-) 539 Protein_2117 IS66 family transposase -
  INV104_RS13070 - 2111977..2112285 (+) 309 Protein_2118 transposase -
  INV104_RS11190 tnpB 2112426..2112680 (-) 255 WP_225415639.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25203.05 Da        Isoelectric Point: 7.7116

>NTDB_id=49205 INV104_RS11160 WP_000649968.1 2107538..2108200(-) (comFC/cflB) [Streptococcus pneumoniae INV104]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQFWCKEGVGVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=49205 INV104_RS11160 WP_000649968.1 2107538..2108200(-) (comFC/cflB) [Streptococcus pneumoniae INV104]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAATTTTGGTGTAAAGAAGGAGTTGGAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z9B1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae TIGR4

99.091

100

0.991
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914
  comFC/cflB Streptococcus mitis NCTC 12261

90.909

100

0.909

Multiple sequence alignment