Detailed information NTG0049177

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: INV104_RS09340
• Genome accession: NC_017591
• Coordinates: 1778226..1779293 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae INV104
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1773226..1784293

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
INV104_RS13835 (INV104_16240)	-	1773727..1774604 (-)	878	Protein_1799	ABC transporter permease	-
INV104_RS09325 (INV104_16250)	-	1774649..1775425 (-)	777	Protein_1800	ABC transporter substrate-binding protein	-
INV104_RS09330 (INV104_16260)	-	1775979..1776932 (-)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-
INV104_RS09335 (INV104_16270)	amiF	1777289..1778215 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
INV104_RS09340 (INV104_16280)	amiE	1778226..1779293 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
INV104_RS09345 (INV104_16290)	amiD	1779302..1780228 (-)	927	WP_000103697.1	oligopeptide ABC transporter permease OppC	Regulator
INV104_RS09350 (INV104_16300)	amiC	1780228..1781724 (-)	1497	WP_000759902.1	ABC transporter permease	Regulator
INV104_RS09355 (INV104_16310)	amiA3	1781791..1783770 (-)	1980	WP_000742233.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=49177 INV104_RS09340 WP_000159554.1 1778226..1779293(-) (amiE) [Streptococcus pneumoniae INV104]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=49177 INV104_RS09340 WP_000159554.1 1778226..1779293(-) (amiE) [Streptococcus pneumoniae INV104]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTCGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGATTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCTATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATTCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541