Detailed information NTG0049043

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SESEC_RS02815
• Genome accession: NC_017582
• Coordinates: 583470..584507 (+)
• Length: 345 a.a.
• NCBI ID: WP_014622492.1
• Uniprot ID: A0A6D2LSH8
• Organism: Streptococcus equi subsp. zooepidemicus ATCC 35246
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 578470..589507

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SESEC_RS02790 (SeseC_00694)	-	578783..580114 (+)	1332	WP_014622489.1	dipeptidase	-
SESEC_RS02795 (SeseC_00695)	arcC	580132..581082 (+)	951	WP_012515218.1	carbamate kinase	-
SESEC_RS02800 (SeseC_00696)	asnA	581301..582293 (+)	993	WP_012515219.1	aspartate--ammonia ligase	-
SESEC_RS02805 (SeseC_00697)	rsmD	582463..583002 (+)	540	WP_014622490.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SESEC_RS02810 (SeseC_00698)	coaD	582992..583492 (+)	501	WP_014622491.1	pantetheine-phosphate adenylyltransferase	-
SESEC_RS02815 (SeseC_00699)	sepM	583470..584507 (+)	1038	WP_014622492.1	SepM family pheromone-processing serine protease	Regulator
SESEC_RS02820 (SeseC_00702)	-	585107..585721 (+)	615	WP_014622493.1	YutD family protein	-
SESEC_RS02825 (SeseC_00703)	rlmN	585725..586807 (+)	1083	WP_014622494.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SESEC_RS02835 (SeseC_00707)	-	588089..588619 (+)	531	WP_014622497.1	Dps family protein	-
SESEC_RS02840 (SeseC_00708)	-	588995..589228 (+)	234	WP_012515231.1	YqgQ family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37450.05 Da
• Isoelectric Point: 9.2833

>NTDB_id=49043 SESEC_RS02815 WP_014622492.1 583470..584507(+) (sepM) [Streptococcus equi subsp. zooepidemicus ATCC 35246]
MKTIKKFKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSVLTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTP
FTEISTMEDTTGGYSDADYLRINRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQVISGDEVDFSTGGVGGPSAGLMF
TLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGGAGLKVAAAAAAGADIFFVPNNPVDKDVKKANPKAISNYEEAKKA
AKRLKTAMKIIPVKTVQDAISYLKK

Nucleotide

• Length: 1038 bp

>NTDB_id=49043 SESEC_RS02815 WP_014622492.1 583470..584507(+) (sepM) [Streptococcus equi subsp. zooepidemicus ATCC 35246]
ATGAAAACAATAAAAAAATTTAAATGGTGGCTGATTGGCTTTGTTGCCTTGCTTTTTCTACTGTTGACACTGTTTTTCCC
CTTGCCTTATTATATTGAAATGCCAGGTGGAGCCTATGATATTCGCTCGGTATTGACTGTCAATGGCAAAGAGGATAAGG
AAAAGGGAGCTTATCAGTTTGTTGTGGTGAGCCTCAGTCGGGCTACCTTGGCTAAATTGCTCTATGCTTGGCTAACGCCT
TTCACTGAGATTAGCACCATGGAAGATACTACTGGTGGCTATAGCGATGCTGATTACCTGCGAATTAATCGCTTTTATAT
GGAAACCTCTCAAAACAGCGCTGTTTACCAGGCCCTTACTCTAGCAGGTAAGGAGGTAAGCTTTGATTATAAGGGTGTTT
ATGTCTTAGACGTCAGCAAGGATTCTAGCTTTAAAGGTGTGCTGCACCTAGCAGATACAGTGACAGGTGTCAATGGTAAA
ACATTTACAACGTCTGCGGATCTGATTGATTATGTTTCTCATTTGACCTTGGGAGATGAGGTGCAGGTACAATTTACAAC
CGCTGGTGAGTCAAAGACTGAAAAAGGAAAGATTATTAAGCTTAAAAACGGTAAAAATGGGATTGGCATTACCCTGACAG
ACCACACACAGGTCATTTCTGGTGATGAGGTCGACTTTAGCACCGGAGGTGTGGGTGGACCAAGTGCAGGCTTGATGTTT
ACTCTTGATATTTATGATCAAATCAATCACGAAGACTTGCGCAAGGGACGTGTGATTGCTGGTACAGGAACCATTGGCAA
GGATGGAAAAGTTGGAGATATTGGCGGGGCGGGCCTAAAGGTGGCTGCCGCCGCCGCTGCTGGTGCTGATATTTTCTTTG
TTCCAAATAATCCTGTGGATAAGGACGTCAAAAAAGCAAATCCTAAGGCTATTAGCAATTACGAGGAGGCTAAAAAAGCA
GCTAAACGACTAAAGACAGCAATGAAAATTATTCCTGTGAAAACCGTTCAAGATGCTATAAGCTACCTTAAAAAATAG

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-311)

3D structure

• AlphaFold DB: A0A6D2LSH8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	70.145	100	0.701