Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   ILP76_RS07210 Genome accession   NZ_CP062469
Coordinates   1436323..1437393 (+) Length   356 a.a.
NCBI ID   WP_194085686.1    Uniprot ID   -
Organism   Staphylococcus aureus strain MRSA - AMRF 4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1431323..1442393
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ILP76_RS07180 (ILP76_07180) - 1431746..1433209 (+) 1464 WP_001017867.1 rhomboid family protein -
  ILP76_RS07185 (ILP76_07185) - 1433190..1433393 (+) 204 WP_000087561.1 YqgQ family protein -
  ILP76_RS07190 (ILP76_07190) - 1433390..1434376 (+) 987 WP_000161315.1 ROK family glucokinase -
  ILP76_RS07195 (ILP76_07195) - 1434376..1434705 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  ILP76_RS07200 (ILP76_07200) - 1434702..1435325 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  ILP76_RS07205 (ILP76_07205) comGA 1435377..1436351 (+) 975 WP_000697219.1 competence type IV pilus ATPase ComGA Machinery gene
  ILP76_RS07210 (ILP76_07210) comGB 1436323..1437393 (+) 1071 WP_194085686.1 competence type IV pilus assembly protein ComGB Machinery gene
  ILP76_RS07215 (ILP76_07215) comGC 1437407..1437718 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  ILP76_RS07220 (ILP76_07220) comGD 1437696..1438142 (+) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  ILP76_RS07225 (ILP76_07225) comGE 1438129..1438428 (+) 300 WP_000844410.1 hypothetical protein Machinery gene
  ILP76_RS07230 (ILP76_07230) comGF 1438346..1438843 (+) 498 WP_029694050.1 competence type IV pilus minor pilin ComGF Machinery gene
  ILP76_RS07235 (ILP76_07235) - 1438940..1439086 (+) 147 WP_001789879.1 hypothetical protein -
  ILP76_RS07240 (ILP76_07240) - 1439076..1439600 (+) 525 WP_001015121.1 shikimate kinase -
  ILP76_RS07245 (ILP76_07245) gcvT 1439759..1440850 (+) 1092 WP_000093345.1 glycine cleavage system aminomethyltransferase GcvT -
  ILP76_RS07250 (ILP76_07250) gcvPA 1440870..1442216 (+) 1347 WP_000019687.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41493.93 Da        Isoelectric Point: 10.0092

>NTDB_id=490291 ILP76_RS07210 WP_194085686.1 1436323..1437393(+) (comGB) [Staphylococcus aureus strain MRSA - AMRF 4]
MKLQWINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIG
YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQCEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=490291 ILP76_RS07210 WP_194085686.1 1436323..1437393(+) (comGB) [Staphylococcus aureus strain MRSA - AMRF 4]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGCCCAACAAATCGATTTACT
TTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA
AAAATAAGCAATTAGGTACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATCAAATATTATCACTGATAGGT
TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATTATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTTTCTATCTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAATTAATTTATAACAATTTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CAGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTGCCTCAAATTTTAGAAAAACTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAATGTG
AAAAGAGAGGGAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACC
AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(27-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

99.719

100

0.997
  comGB Staphylococcus aureus N315

99.719

100

0.997