Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ILP77_RS08105 Genome accession   NZ_CP062467
Coordinates   1650848..1651564 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain MRSA - AMRF 5     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1645848..1656564
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ILP77_RS08085 (ILP77_08085) - 1646940..1647890 (+) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -
  ILP77_RS08090 (ILP77_08090) - 1648039..1649523 (+) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  ILP77_RS08095 (ILP77_08095) - 1649520..1650479 (+) 960 WP_001253308.1 carbohydrate kinase family protein -
  ILP77_RS08100 (ILP77_08100) - 1650667..1650776 (-) 110 Protein_1597 hypothetical protein -
  ILP77_RS08105 (ILP77_08105) agrA 1650848..1651564 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ILP77_RS08110 (ILP77_08110) agrC 1651583..1652866 (-) 1284 WP_194085750.1 quorum-sensing sensor histidine kinase AgrC -
  ILP77_RS08115 (ILP77_08115) agrD 1652896..1653039 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  ILP77_RS08120 (ILP77_08120) - 1653042..1653605 (-) 564 WP_001105696.1 accessory gene regulator AgrB -
  ILP77_RS14880 hld 1653895..1653975 (+) 81 WP_000046022.1 delta-hemolysin -
  ILP77_RS08130 (ILP77_08130) - 1654575..1655360 (-) 786 WP_194085751.1 carbon-nitrogen family hydrolase -
  ILP77_RS08135 (ILP77_08135) - 1655721..1656347 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=490237 ILP77_RS08105 WP_000688492.1 1650848..1651564(-) (agrA) [Staphylococcus aureus strain MRSA - AMRF 5]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=490237 ILP77_RS08105 WP_000688492.1 1650848..1651564(-) (agrA) [Staphylococcus aureus strain MRSA - AMRF 5]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1