Detailed information NTG0490052

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF697_RS10220
• Genome accession: NZ_CP062419
• Coordinates: 2098483..2099370 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain NAS_AN_023
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2093483..2104370

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF697_RS10190 (IF697_10150)	-	2094215..2094976 (+)	762	WP_000323447.1	alpha/beta hydrolase family protein	-
IF697_RS10195 (IF697_10155)	-	2095221..2095676 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF697_RS13585	-	2095798..2095899 (+)	102	WP_000731972.1	SE2200 family small protein	-
IF697_RS10205 (IF697_10165)	-	2095959..2097383 (-)	1425	WP_000953762.1	alkaline phosphatase	-
IF697_RS10210 (IF697_10170)	-	2097581..2097781 (+)	201	WP_000604727.1	hypothetical protein	-
IF697_RS10215 (IF697_10175)	braR	2097807..2098472 (+)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF697_RS10220 (IF697_10180)	braS	2098483..2099370 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF697_RS10225 (IF697_10185)	-	2099479..2100234 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IF697_RS10230 (IF697_10190)	-	2100231..2102231 (+)	2001	WP_000776739.1	ABC transporter permease	-
IF697_RS10235 (IF697_10195)	-	2102890..2103003 (+)	114	Protein_1982	hypothetical protein	-
IF697_RS10240 (IF697_10200)	-	2103385..2103645 (+)	261	WP_001789910.1	hypothetical protein	-
IF697_RS10245 (IF697_10205)	-	2103655..2104152 (+)	498	WP_001065269.1	glutathione peroxidase	-
IF697_RS10250 (IF697_10210)	-	2104260..2104352 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=490052 IF697_RS10220 WP_000143420.1 2098483..2099370(+) (braS) [Staphylococcus aureus strain NAS_AN_023]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=490052 IF697_RS10220 WP_000143420.1 2098483..2099370(+) (braS) [Staphylococcus aureus strain NAS_AN_023]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993