Detailed information NTG0048998

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: STH8232_RS05835
• Genome accession: NC_017581
• Coordinates: 1118023..1118904 (-)
• Length: 293 a.a.
• NCBI ID: WP_014621666.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus JIM 8232
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1113023..1123904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STH8232_RS05810 (STH8232_1346)	vicR	1113731..1114438 (-)	708	WP_011226084.1	response regulator YycF	Regulator
STH8232_RS05815 (STH8232_1347)	-	1114962..1115729 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
STH8232_RS05820 (STH8232_1348)	-	1115741..1116574 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
STH8232_RS05825 (STH8232_1349)	-	1116592..1117290 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
STH8232_RS05830 (STH8232_1350)	-	1117302..1117952 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
STH8232_RS05835 (STH8232_1351)	endA	1118023..1118904 (-)	882	WP_014621666.1	DNA/RNA non-specific endonuclease	Machinery gene
STH8232_RS05840 (STH8232_1352)	-	1118966..1119154 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
STH8232_RS05845 (STH8232_1353)	murA	1119156..1120427 (-)	1272	WP_014621667.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STH8232_RS05850 (STH8232_1354)	-	1120497..1120733 (-)	237	WP_002946959.1	DUF1146 family protein	-
STH8232_RS05855 (STH8232_1355)	galE	1120921..1121934 (-)	1014	WP_014621668.1	UDP-glucose 4-epimerase GalE	-
STH8232_RS05860 (STH8232_1356)	-	1121949..1123358 (-)	1410	WP_406701479.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31818.50 Da
• Isoelectric Point: 10.0477

>NTDB_id=48998 STH8232_RS05835 WP_014621666.1 1118023..1118904(-) (endA) [Streptococcus thermophilus JIM 8232]
MVERKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLSETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=48998 STH8232_RS05835 WP_014621666.1 1118023..1118904(-) (endA) [Streptococcus thermophilus JIM 8232]
ATGGTAGAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTAATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTTCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGACGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCTTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.385	81.57	0.59
endA	Streptococcus pneumoniae D39	72.385	81.57	0.59
endA	Streptococcus pneumoniae R6	72.385	81.57	0.59
endA	Streptococcus pneumoniae TIGR4	72.385	81.57	0.59