Detailed information NTG0489843

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF723_RS10225
• Genome accession: NZ_CP062414
• Coordinates: 2096991..2097878 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain NAS_AN_175
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2091991..2102878

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF723_RS10195 (IF723_10125)	-	2092723..2093484 (+)	762	WP_000323447.1	alpha/beta hydrolase family protein	-
IF723_RS10200 (IF723_10130)	-	2093729..2094184 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF723_RS13615	-	2094306..2094407 (+)	102	WP_000731972.1	SE2200 family small protein	-
IF723_RS10210 (IF723_10140)	-	2094467..2095891 (-)	1425	WP_000953762.1	alkaline phosphatase	-
IF723_RS10215 (IF723_10145)	-	2096089..2096289 (+)	201	WP_000604727.1	hypothetical protein	-
IF723_RS10220 (IF723_10150)	braR	2096315..2096980 (+)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF723_RS10225 (IF723_10155)	braS	2096991..2097878 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF723_RS10230 (IF723_10160)	-	2097987..2098742 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IF723_RS10235 (IF723_10165)	-	2098739..2100739 (+)	2001	WP_000776739.1	ABC transporter permease	-
IF723_RS10240 (IF723_10170)	-	2101398..2101511 (+)	114	Protein_1983	hypothetical protein	-
IF723_RS10245 (IF723_10175)	-	2101893..2102153 (+)	261	WP_001789910.1	hypothetical protein	-
IF723_RS10250 (IF723_10180)	-	2102163..2102660 (+)	498	WP_001065269.1	glutathione peroxidase	-
IF723_RS10255 (IF723_10185)	-	2102768..2102860 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=489843 IF723_RS10225 WP_000143420.1 2096991..2097878(+) (braS) [Staphylococcus aureus strain NAS_AN_175]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=489843 IF723_RS10225 WP_000143420.1 2096991..2097878(+) (braS) [Staphylococcus aureus strain NAS_AN_175]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993