Detailed information NTG0489758

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF725_RS10210
• Genome accession: NZ_CP062412
• Coordinates: 2095866..2096753 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain NAS_AN_181
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2090866..2101753

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF725_RS10180 (IF725_10145)	-	2091598..2092359 (+)	762	WP_000323447.1	alpha/beta hydrolase family protein	-
IF725_RS10185 (IF725_10150)	-	2092604..2093059 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF725_RS13610	-	2093181..2093282 (+)	102	WP_000731972.1	SE2200 family small protein	-
IF725_RS10195 (IF725_10160)	-	2093342..2094766 (-)	1425	WP_000953762.1	alkaline phosphatase	-
IF725_RS10200 (IF725_10165)	-	2094964..2095164 (+)	201	WP_000604727.1	hypothetical protein	-
IF725_RS10205 (IF725_10170)	braR	2095190..2095855 (+)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF725_RS10210 (IF725_10175)	braS	2095866..2096753 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF725_RS10215 (IF725_10180)	-	2096862..2097617 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IF725_RS10220 (IF725_10185)	-	2097614..2099614 (+)	2001	WP_000776739.1	ABC transporter permease	-
IF725_RS10225 (IF725_10190)	-	2100273..2100386 (+)	114	Protein_1982	hypothetical protein	-
IF725_RS10230 (IF725_10195)	-	2100768..2101028 (+)	261	WP_001789910.1	hypothetical protein	-
IF725_RS10235 (IF725_10200)	-	2101038..2101535 (+)	498	WP_001065269.1	glutathione peroxidase	-
IF725_RS10240 (IF725_10205)	-	2101643..2101735 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=489758 IF725_RS10210 WP_000143420.1 2095866..2096753(+) (braS) [Staphylococcus aureus strain NAS_AN_181]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=489758 IF725_RS10210 WP_000143420.1 2095866..2096753(+) (braS) [Staphylococcus aureus strain NAS_AN_181]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993