Detailed information NTG0048969

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: STH8232_RS00570
• Genome accession: NC_017581
• Coordinates: 90824..93274 (+)
• Length: 816 a.a.
• NCBI ID: WP_041828978.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus JIM 8232
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 85824..98274

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STH8232_RS00545 (STH8232_0112)	ahpC	86792..87352 (-)	561	WP_002886340.1	alkyl hydroperoxide reductase subunit C	-
STH8232_RS00550 (STH8232_0113)	rpsB	87626..88393 (+)	768	WP_002944541.1	30S ribosomal protein S2	-
STH8232_RS00555 (STH8232_0114)	tsf	88504..89544 (+)	1041	WP_014621027.1	translation elongation factor Ts	-
STH8232_RS00560 (STH8232_0115)	-	89654..90124 (-)	471	WP_014621028.1	COG2426 family protein	-
STH8232_RS00565 (STH8232_0116)	-	90368..90823 (+)	456	WP_014621029.1	CtsR family transcriptional regulator	-
STH8232_RS00570 (STH8232_0117)	clpC	90824..93274 (+)	2451	WP_041828978.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
STH8232_RS10980	pbp3	93402..94658 (-)	1257	Protein_72	D-alanyl-D-alanine carboxypeptidase PBP3	-
STH8232_RS00580 (STH8232_0121)	pbp3	94803..96050 (-)	1248	WP_014621034.1	D-alanyl-D-alanine carboxypeptidase PBP3	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90398.69 Da
• Isoelectric Point: 6.0827

>NTDB_id=48969 STH8232_RS00570 WP_041828978.1 90824..93274(+) (clpC) [Streptococcus thermophilus JIM 8232]
MTIYSRKMQAIFHRAQLEAERFESPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIHSEEIETAAVLAMEKRPKDLSKSDI
IDLRAQSPALEAMLQEAQGIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERNAGLS
KQDLKAIHDLRKPKKSKASANFANMMQPPQSSTGELADYTKDLTALAESGNLDPVIGRDEEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVSEAIDILNGLRSSYEDYHRVTI
TDAAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQVRIKKEAKREITPLDEALISGDIRAAVKQYKANQKAKFPKPTL
VDADQIMQTLSRLSGIPVEKMTQTDSKRYLNLESELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEIEKAHPDIFNVL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAQTISHNHQAMQARIMEELKKSYRPEFINRIDEKVV
FHSLEEEQLHDIVKIMVKPLISALADKGISLKFQPAALKHLAKDGYDIEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=48969 STH8232_RS00570 WP_041828978.1 90824..93274(+) (clpC) [Streptococcus thermophilus JIM 8232]
ATGACGATATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAAGCGGAGCGTTTTGAAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCGGGATCTGTAGCCTACTTAACATTTACTGATTTTGAGGACC
GTATTCATTCGGAAGAGATTGAGACAGCTGCTGTATTGGCTATGGAGAAGAGGCCAAAAGACTTGTCGAAATCAGATATT
ATCGATTTACGTGCACAGTCACCTGCGCTAGAGGCTATGTTGCAAGAGGCGCAAGGAATCGCTAGTGTGACTGGTGCTGT
AGAGGTGGGGTCTGAACATGTATTGATGGCCTTCCTTCTTCATAAGGATTTAATGGTTTGTCGCCTCCTTGAAGTGGCTG
GTTTTCAATATAAAGATGATAGCGATAAACCTCGCATCATAGATTTACGACGTTCTTTGGAGCGTAATGCTGGTCTTAGC
AAGCAAGATTTGAAGGCAATTCACGATCTTCGTAAACCTAAGAAATCAAAAGCATCTGCGAATTTTGCCAATATGATGCA
ACCTCCTCAATCATCTACTGGTGAACTGGCAGATTATACCAAAGACTTAACTGCATTAGCGGAGTCAGGAAATCTTGATC
CCGTTATTGGACGCGATGAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAATCCTGTCTTGGTA
GGTGAAGCTGGTGTCGGTAAGACAGCACTTGCTCTTGGTTTAGCGCAACGTATTGCTTCAGGCGAAGTACCATTTGAATT
GGCTGATATGCGTATCTTAGAGCTTGACATGATGAGCGTTGTTGCAGGGACACGTTTCCGTGGTGATTTCGAAGAGCGTA
TGAATCAGATTATTGATGAGATTGAAGCTGATGGGAAAATCATTCTCTTTATTGACGAACTACATACGATTATTGGATCT
GGTTCAGGTATTGATAGTACCTTGGATGCGGCTAATATTTTGAAACCGGCCCTTGCGCGCGGGACACTTCACATGGTTGG
AGCAACCACGCAAGCTGAATACCAAAAGCATATTGAGAAAGATGCAGCTTTATCCCGTCGTTTTGCTAAAATTACAATTG
AAGAACCAAGTGTATCTGAAGCAATCGATATTTTAAACGGTTTGCGTTCGTCTTATGAAGACTATCATCGTGTGACTATT
ACGGACGCGGCAGTTGAGACGGCAGTCAAGGCAGCGCATCGCTATTTGACGAGTAAGAATTTGCCTGATTCGGCAATTGA
CCTTTTAGATGAAGCGAGTGCAACTGTTCAAGTTCGTATCAAAAAAGAGGCCAAACGTGAGATAACGCCTTTGGATGAAG
CACTTATATCTGGGGATATTAGGGCTGCTGTTAAACAGTATAAGGCTAACCAAAAGGCAAAATTTCCTAAACCTACTTTA
GTAGATGCGGATCAGATTATGCAAACTCTTAGTCGTTTATCAGGTATCCCTGTTGAGAAGATGACGCAGACTGACAGCAA
GCGTTACCTGAATCTTGAATCAGAACTCCACAAACGTGTTATTGGTCAAGATGAGGCGGTTTCGGCTATCAGCCGTGCTA
TTCGTCGTAATCAGTCAGGTATTCGTACTGGAAAACGTCCTATTGGCTCCTTCATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAATTGGCCAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAATCAGCTTTGCTTCGCTTTGATATGTCGGAGTA
TATGGAAAAATTTGCGGCTAGTCGCCTTAATGGTGCTCCTCCAGGGTATGTCGGATATGATGAGGGTGGAGAGTTGACAG
AGAAAGTTCGAAATAAGCCCTACTCAGTTCTTCTCTTTGACGAGATTGAGAAAGCTCATCCAGATATCTTCAACGTTCTC
TTACAGGTTTTGGATGACGGTGTTTTAACAGATAGCCGTGGTCGTAAGGTTGATTTTTCAAACACTATCATCATTATGAC
CTCAAATTTGGGAGCTACAGCTCTTCGTGATGATAAAACTGTTGGTTTTGGTGCTCAAACTATTTCTCATAATCACCAAG
CCATGCAAGCACGCATTATGGAAGAGCTTAAGAAGTCCTATCGTCCAGAATTTATTAACCGTATTGATGAGAAGGTTGTC
TTCCACAGCTTAGAGGAAGAACAACTACATGACATTGTCAAGATTATGGTTAAACCATTAATTTCAGCTCTAGCCGATAA
AGGTATAAGCTTAAAATTCCAACCAGCTGCTCTTAAGCATTTGGCTAAGGATGGCTATGATATTGAGATGGGAGCTCGTC
CATTACGTCGTACGATTCAAACTCAAGTGGAGGACAAGTTGTCTGAGTTATTACTAGGTGGCCAAGTTGTTAGCGGACAG
ACCCTTAAGATTGGTTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• AAA lid domain (AAA_lid_9) (377-456)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (107-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	99.51	100	0.995
clpC	Streptococcus thermophilus LMD-9	99.142	100	0.991
clpC	Streptococcus mutans UA159	72.426	100	0.724
clpC	Streptococcus pneumoniae TIGR4	66.093	99.755	0.659
clpC	Streptococcus pneumoniae Rx1	66.093	99.755	0.659
clpC	Streptococcus pneumoniae D39	66.093	99.755	0.659
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.421	100	0.513
clpC	Bacillus subtilis subsp. subtilis str. 168	47.016	100	0.473
clpE	Streptococcus mutans UA159	47.52	76.593	0.364