Detailed information NTG0489673

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF729_RS10445
• Genome accession: NZ_CP062410
• Coordinates: 2124705..2125592 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain NAS_AN_205
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2119705..2130592

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF729_RS10415 (IF729_10360)	-	2120437..2121198 (+)	762	WP_000323441.1	alpha/beta hydrolase family protein	-
IF729_RS10420 (IF729_10365)	-	2121443..2121898 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF729_RS13875	-	2122020..2122121 (+)	102	WP_000731976.1	SE2200 family small protein	-
IF729_RS10430 (IF729_10375)	-	2122181..2123605 (-)	1425	WP_000953755.1	alkaline phosphatase	-
IF729_RS10435 (IF729_10380)	-	2123803..2124003 (+)	201	WP_000604730.1	hypothetical protein	-
IF729_RS10440 (IF729_10385)	braR	2124029..2124694 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF729_RS10445 (IF729_10390)	braS	2124705..2125592 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF729_RS10450 (IF729_10395)	-	2125700..2126455 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IF729_RS10455 (IF729_10400)	-	2126452..2128452 (+)	2001	WP_000776751.1	ABC transporter permease	-
IF729_RS10460 (IF729_10405)	-	2129111..2129224 (+)	114	Protein_2028	hypothetical protein	-
IF729_RS10465 (IF729_10410)	-	2129606..2129866 (+)	261	WP_001791974.1	hypothetical protein	-
IF729_RS10470 (IF729_10415)	-	2129876..2130373 (+)	498	WP_001065268.1	glutathione peroxidase	-
IF729_RS10475 (IF729_10420)	-	2130481..2130573 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=489673 IF729_RS10445 WP_000143425.1 2124705..2125592(+) (braS) [Staphylococcus aureus strain NAS_AN_205]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=489673 IF729_RS10445 WP_000143425.1 2124705..2125592(+) (braS) [Staphylococcus aureus strain NAS_AN_205]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1