Detailed information NTG0489630

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF734_RS10145
• Genome accession: NZ_CP062409
• Coordinates: 2083416..2084303 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain NAS_AN_239
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2078416..2089303

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF734_RS10115 (IF734_10050)	-	2079148..2079909 (+)	762	WP_000323441.1	alpha/beta hydrolase family protein	-
IF734_RS10120 (IF734_10055)	-	2080154..2080609 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF734_RS13570	-	2080731..2080832 (+)	102	WP_000731976.1	SE2200 family small protein	-
IF734_RS10130 (IF734_10065)	-	2080892..2082316 (-)	1425	WP_000953755.1	alkaline phosphatase	-
IF734_RS10135 (IF734_10070)	-	2082514..2082714 (+)	201	WP_000604730.1	hypothetical protein	-
IF734_RS10140 (IF734_10075)	braR	2082740..2083405 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF734_RS10145 (IF734_10080)	braS	2083416..2084303 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF734_RS10150 (IF734_10085)	-	2084411..2085166 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IF734_RS10155 (IF734_10090)	-	2085163..2087163 (+)	2001	WP_000776751.1	ABC transporter permease	-
IF734_RS10160 (IF734_10095)	-	2087822..2087935 (+)	114	Protein_1968	hypothetical protein	-
IF734_RS10165 (IF734_10100)	-	2088317..2088577 (+)	261	WP_001791974.1	hypothetical protein	-
IF734_RS10170 (IF734_10105)	-	2088587..2089084 (+)	498	WP_001065268.1	glutathione peroxidase	-
IF734_RS10175 (IF734_10110)	-	2089192..2089284 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=489630 IF734_RS10145 WP_000143425.1 2083416..2084303(+) (braS) [Staphylococcus aureus strain NAS_AN_239]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=489630 IF734_RS10145 WP_000143425.1 2083416..2084303(+) (braS) [Staphylococcus aureus strain NAS_AN_239]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1