Detailed information NTG0489588

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF735_RS10730
• Genome accession: NZ_CP062408
• Coordinates: 2178956..2179843 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain NAS_AN_247
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2173956..2184843

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF735_RS10700 (IF735_10665)	-	2174688..2175449 (+)	762	WP_000323447.1	alpha/beta hydrolase family protein	-
IF735_RS10705 (IF735_10670)	-	2175694..2176149 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF735_RS14130	-	2176271..2176372 (+)	102	WP_000731972.1	SE2200 family small protein	-
IF735_RS10715 (IF735_10680)	-	2176432..2177856 (-)	1425	WP_000953762.1	alkaline phosphatase	-
IF735_RS10720 (IF735_10685)	-	2178054..2178254 (+)	201	WP_000604727.1	hypothetical protein	-
IF735_RS10725 (IF735_10690)	braR	2178280..2178945 (+)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF735_RS10730 (IF735_10695)	braS	2178956..2179843 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF735_RS10735 (IF735_10700)	-	2179952..2180707 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IF735_RS10740 (IF735_10705)	-	2180704..2182704 (+)	2001	WP_000776739.1	ABC transporter permease	-
IF735_RS10745 (IF735_10710)	-	2183363..2183476 (+)	114	Protein_2085	hypothetical protein	-
IF735_RS10750 (IF735_10715)	-	2183858..2184118 (+)	261	WP_001789910.1	hypothetical protein	-
IF735_RS10755 (IF735_10720)	-	2184128..2184625 (+)	498	WP_001065269.1	glutathione peroxidase	-
IF735_RS10760 (IF735_10725)	-	2184733..2184825 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=489588 IF735_RS10730 WP_000143420.1 2178956..2179843(+) (braS) [Staphylococcus aureus strain NAS_AN_247]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=489588 IF735_RS10730 WP_000143420.1 2178956..2179843(+) (braS) [Staphylococcus aureus strain NAS_AN_247]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993