Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   IF757_RS06370 Genome accession   NZ_CP062404
Coordinates   1294823..1295893 (-) Length   356 a.a.
NCBI ID   WP_000776412.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NAS_NP_229     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1289823..1300893
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF757_RS06330 (IF757_06300) gcvPA 1290000..1291346 (-) 1347 WP_000019697.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -
  IF757_RS06335 (IF757_06305) gcvT 1291366..1292457 (-) 1092 WP_000093347.1 glycine cleavage system aminomethyltransferase GcvT -
  IF757_RS06340 (IF757_06310) - 1292616..1293140 (-) 525 WP_001015125.1 shikimate kinase -
  IF757_RS06345 (IF757_06315) - 1293130..1293276 (-) 147 WP_001789879.1 hypothetical protein -
  IF757_RS06350 (IF757_06320) comGF 1293373..1293870 (-) 498 WP_001794055.1 competence type IV pilus minor pilin ComGF Machinery gene
  IF757_RS06355 (IF757_06325) comGE 1293788..1294087 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  IF757_RS06360 (IF757_06330) comGD 1294074..1294520 (-) 447 WP_001791207.1 competence type IV pilus minor pilin ComGD Machinery gene
  IF757_RS06365 (IF757_06335) comGC 1294498..1294809 (-) 312 WP_000472257.1 competence type IV pilus major pilin ComGC Machinery gene
  IF757_RS06370 (IF757_06340) comGB 1294823..1295893 (-) 1071 WP_000776412.1 competence type IV pilus assembly protein ComGB Machinery gene
  IF757_RS06375 (IF757_06345) comGA 1295865..1296839 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  IF757_RS06380 (IF757_06350) - 1296891..1297514 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  IF757_RS06385 (IF757_06355) - 1297511..1297840 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  IF757_RS06390 (IF757_06360) - 1297840..1298826 (-) 987 WP_000161314.1 ROK family glucokinase -
  IF757_RS06395 (IF757_06365) - 1298823..1299026 (-) 204 WP_000087561.1 YqgQ family protein -
  IF757_RS06400 (IF757_06370) - 1299007..1300470 (-) 1464 WP_001017873.1 rhomboid family intramembrane serine protease -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41429.85 Da        Isoelectric Point: 10.1030

>NTDB_id=489402 IF757_RS06370 WP_000776412.1 1294823..1295893(-) (comGB) [Staphylococcus aureus strain NAS_NP_229]
MKLQWINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNKILSLIG
YSDTIVLQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=489402 IF757_RS06370 WP_000776412.1 1294823..1295893(-) (comGB) [Staphylococcus aureus strain NAS_NP_229]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGCCCAACAAATCGATTTACT
TTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA
AAAATAAGCAATTAGGTACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATAAGATATTATCACTGATAGGT
TATAGCGATACTATCGTCCTGCAAGTATATTTGGCAGAAAGATTTGGCAATATCATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTTTCTATTTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAATTAATTTATAACAATTTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CAGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTGCCTCAAATTTTAGAAAAACTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG
AAAAGAGAGGGAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACC
GATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(27-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

99.438

100

0.994
  comGB Staphylococcus aureus N315

99.438

100

0.994