Detailed information NTG0489260

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: IF770_RS00790
• Genome accession: NZ_CP062401
• Coordinates: 124582..125625 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain NAS_OP_098
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 119582..130625

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF770_RS00760 (IF770_00760)	-	120008..120118 (+)	111	WP_001790257.1	hypothetical protein	-
IF770_RS00765 (IF770_00765)	-	120147..120560 (+)	414	WP_001557448.1	hypothetical protein	-
IF770_RS00770 (IF770_00770)	-	120991..121977 (-)	987	WP_000999717.1	aromatic acid exporter family protein	-
IF770_RS00775 (IF770_00775)	map	122508..123266 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
IF770_RS00780 (IF770_00780)	-	123483..123869 (+)	387	WP_001110179.1	hypothetical protein	-
IF770_RS00785 (IF770_00785)	liaF	123884..124585 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
IF770_RS00790 (IF770_00790)	vraS	124582..125625 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
IF770_RS00795 (IF770_00795)	vraR	125615..126244 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
IF770_RS00800 (IF770_00800)	-	126357..127574 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
IF770_RS00805 (IF770_00805)	-	127852..128127 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
IF770_RS00810 (IF770_00810)	-	128134..128598 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
IF770_RS00815 (IF770_00815)	-	128745..128945 (+)	201	WP_000180460.1	DUF1128 family protein	-
IF770_RS00820 (IF770_00820)	-	128948..130204 (+)	1257	WP_001795108.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=489260 IF770_RS00790 WP_001017131.1 124582..125625(+) (vraS) [Staphylococcus aureus strain NAS_OP_098]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=489260 IF770_RS00790 WP_001017131.1 124582..125625(+) (vraS) [Staphylococcus aureus strain NAS_OP_098]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1