Detailed information NTG0488963

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF701_RS10205
• Genome accession: NZ_CP062386
• Coordinates: 2098962..2099849 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain NAS_AN_047
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2093962..2104849

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF701_RS10175 (IF701_10145)	-	2094694..2095455 (+)	762	WP_000323447.1	alpha/beta hydrolase family protein	-
IF701_RS10180 (IF701_10150)	-	2095700..2096155 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF701_RS13640	-	2096277..2096378 (+)	102	WP_000731972.1	SE2200 family small protein	-
IF701_RS10190 (IF701_10160)	-	2096438..2097862 (-)	1425	WP_000953762.1	alkaline phosphatase	-
IF701_RS10195 (IF701_10165)	-	2098060..2098260 (+)	201	WP_000604727.1	hypothetical protein	-
IF701_RS10200 (IF701_10170)	braR	2098286..2098951 (+)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF701_RS10205 (IF701_10175)	braS	2098962..2099849 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF701_RS10210 (IF701_10180)	-	2099958..2100713 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IF701_RS10215 (IF701_10185)	-	2100710..2102710 (+)	2001	WP_000776739.1	ABC transporter permease	-
IF701_RS10220 (IF701_10190)	-	2103368..2103481 (+)	114	Protein_1981	hypothetical protein	-
IF701_RS10225 (IF701_10195)	-	2103863..2104123 (+)	261	WP_001789910.1	hypothetical protein	-
IF701_RS10230 (IF701_10200)	-	2104133..2104630 (+)	498	WP_001065269.1	glutathione peroxidase	-
IF701_RS10235 (IF701_10205)	-	2104738..2104830 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=488963 IF701_RS10205 WP_000143420.1 2098962..2099849(+) (braS) [Staphylococcus aureus strain NAS_AN_047]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=488963 IF701_RS10205 WP_000143420.1 2098962..2099849(+) (braS) [Staphylococcus aureus strain NAS_AN_047]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993